adenovirus

adenovirus

1. A 10 MOI of recombinant nonreplicating adenovirus was found to infect more than 90% of HOS cells within 24 hours by EGFP fluorescence, in which the MPG overexpression and MPG enzyme activity were also detected.

10个感染增殖指数(MOI)的Ad5HA-MPG可使90%以上HOS感染,感染细胞高表达MPG并具有MPG酶活性。

2. When 293 cell line, human embryonic kidney cells transformed by adenovirus type 5 DNA, was infected by BK virus (BKV ), a widespread human papovavirus-the initial cytopathic effects (CPE ) occurea in 7 days and the complete CPE, in 3 weeks.

293细胞系乃是由腺病毒5的DNA转化的人胚肾细胞,被BK病毒(BKV,一种广泛分布的人类乳多空病毒)感染后,七天内出现最早的细胞病变,三周后可见完全的细胞病变.

3. Keywords adenovirus type 3;Hexon;expressing;recombinant plasmid;

3型腺病毒;六邻体;表达;重组质粒;

4. Coxsaelde and adenovirus receptor (CAR)

CAR受体

5. Cerepro harnesses an adenovirus, a type of virus which carries its DNA in double-stranded form, to transmit a gene responsible for the production of a protein called thymidine kinase.

Cerepro被固定在一个腺病毒（一种能够携带双链形式的DNA病毒）上来传染基因，这个基因负责产生胸苷激酶这种蛋白质。

6. A segment of DNA is inserted into the genome of an adenovirus (a species of virus able to get inside the nucleus of human cells), which is then injected directly into the tumour.

DNA部分片断被嵌入到腺病毒的基因组（一种病毒能够进入到人类细胞的内核），之后就被直接注射到肿瘤当中。

7. E1B gene-deleted adenovirus (H101)

E1B缺失腺病毒

8. Keywords EBV;recombinant adenovirus;LMP2A;gastric cancer cell;

EB病毒;重组腺病毒;潜伏期膜蛋白2A;胃癌细胞;

9. Keywords KAI1 gene;Adenovirus vector;Gene therapy;

KAI1基因;腺病毒载体;基因治疗;

10. The constructed pDC316-LMP2 was co-transfected with adenovirus backbone pBHG-fiber5/35 into 293 cells to establish the recombinant adenovirus Ad5F35-LMP2, which was confirmed by PCR and indirect immune-fluorescence test.

pDC3l6-LMP2与腺病毒骨架pBHG-fiber5/35共转染293细胞构建重组腺病毒Ad5F35-LMP2,PCR及间接免疫荧光进行鉴定。

11. Construction of recombinant adenovirus encoding PTEN cDNA

PTEN cDNA重组腺病毒载体的构建

12. Recombinant T-bet adenovirus

T-bet重组腺病毒

13. "The failure of the Merck vaccine up on behalf of the non-replicating adenovirus vector vaccine failure, not on behalf of other AIDS vaccines will be no hope.

“默克疫苗的失败至多代表非复制型腺病毒载体疫苗的失败，决不代表其他艾滋病疫苗就没有希望。”

14. A simple method for rapid construction of recombinant adenovirus

一种快速构建重组腺病毒的简便方法

15. ONYX-015, a ElB-deleted adenovirus mutant replicates efficiently in p53-abnormal cells and results in the lysis of the tumors, but do not do so in p53-normal cells.

一种腺病毒E1B缺失体ONYX-015能够在p53突变的肿瘤细胞内有效地复制而导致痛细胞的裂解,但不能在p53正常的细胞内复制。

16. Laboratory tests for three of discharged patients showed adenovirus in 2 and parainfluenza type 3 in one.

三名出院病人的化验显示,其中2名为腺病毒,另一名为副流感3型。

17. Atypical pneumonia is mainly caused by viruses such as influenza and adenovirus, bacteria such as chlamydia and mycoplasma, and other unknown agents.

严重急性呼吸系统综合症主要是由流感病毒和腺病毒、菌如支原体和衣原体以及其他未明的微生物所引起的肺炎。

18. Here we construct a hTERT and Cox-2 promoter regulated oncolytic virus byreplace the endogenous adenovirus El a and Elb promoter respectively.

为下一步进行腺病毒在293细胞的包装、纯化、以及病毒感染各种肿瘤细胞、病毒感染治疗动物实体瘤模型奠定基础。

19. Keywords Breast cancer;Gene therapy;Adenovirus;Apoptosis;

乳腺癌;基因治疗;腺病毒;凋亡;

20. Keywords humanIL 12;DNA sequence;adenovirus vector;IRES;

人白介素12;DNA测序;腺病毒载体;内核糖体进入位点;

21. adenovirus vector mediated hepatocyte growth factor gene

人重组腺病毒介导肝细胞生长因子基因

22. A canine adenovirus (CAV) strain,tentatively named YCA18,was isolated from a 3 month old sick pup.

从一只 3月龄病犬中分离出一株犬腺病毒 ( CAV) ,暂定名为 YCA1 8。

23. But it seems that trial participants who had a pre-existing immunity to adenovirus 5 were more likely to become HIV-positive if they received the vaccine.

但实验人群中曾对腺病毒5感染有过免疫反应的人群在注射疫苗之后，似乎更容易转变成HIV阳性。

24. Studies in vitro as in vivo demonstrated that recombinant EGFR antisense adenovirus can effectively inhibit the proliferaion of endothelial cells and tumoral angiogenesis.

体外及体内研究均显示，EGFR反义重组腺病毒可有效地抑制血管内皮细胞的增殖和肿瘤内血管的生成。

25. The viruses that are commonly used for this purpose are adenovirus, adeno-associated virus (AAV), retrovirus, lentivirus and herpes virus.

使用的病毒可以是腺病毒、AAV、反转录病毒、疱疹病毒。

26. For example, in the United States, rotavirus and astrovirus infections occur during the cooler months of the year (October to April), whereas adenovirus infections occur throughout the year.

例如，在美国，轮状病毒和星状病毒的传染常出现在一年中较冷的月份（10月到来年四月之间)，而腺病毒传染则整年发生。

27. Keywords mammary cancer;adenovirus;gene therapy;CDES gene;

关键词乳腺癌;腺病毒;基因疗法;CDES基因;

28. Keywords Amphiregulin Antisense Adenovirus Breast cancer ;

关键词双调蛋白;反义;腺病毒;乳腺癌;

29. Among them, adenovirus 36 was the first human pathogen reported to cause obesity.

其中腺病毒36型是第一个被发现在动物中可以导致肥胖的人类腺病毒。

30. "Likewise, most people infected by the suspect adenovirus do not appear to become seriously ill.

华盛顿邮报报道说：同样的，大多数被腺病毒感染的人也不见得会变得如此严重。

31. replication-competent adenovirus

可复制型腺病毒

32. "Likewise, most people infected by the suspect adenovirus do not appear to become seriously ill.But the germ appears to be spreading, and investigators are unsure how much of a threat it poses.

同样的，大多数被这种可疑的腺病毒感染的人的病看起来并不会变得特别严重，但是细菌似乎会扩散，研究人员并不确定它将产生多大的威胁。

33. PCR showed that the adenovirus contained EWS-FLI1(cDNA.)

同源重组后产生的pADeasy-1/EW S-FLI1经PCR鉴定构建成功,纯化后的滴度为4×1010/mL。

34. Successful construction of the recombinant adenovirus vector containing the Ki67-siRNA gene was achieved and it can be used to significantly inhibit expression of the Ki67 gene and the growth human colon carcinoma cells.

含有Ki67-siRNA的重组腺病毒构建成功,其能抑制人结肠癌细胞Ki67基因表达和生长。

35. Respiratory syncytial virus and adenovirus are two causes of pediatric common lower respiratory tract infection, threatening the health of children.

呼吸道合胞病毒和腺病毒是小儿常见的下呼吸道感染的两个病原，严重威胁小儿的健康。

36. Mammalina adenovirus subgroup

哺乳动物腺病毒亚群

37. Houyanqing buccal tablet could inhibite CPE caused by influenza virus(A 3), parainfluenza virus(HVJ),adenovirus(AdV 3, AdV 7) and herpes simplex virus(HSV 1,HSV 2).

喉咽清含片对流感病毒甲 3型 (A3)、副流感病毒 1型 (HVJ)、腺病毒 (AdV3,AdV7)及疱疹病毒 (HSV 1,HSV 2 )所致细胞病变效应有抑制作用 ;

38. Adenovirus is the main candidate for expressing and delivering therapy genes because of its intensive tissue tropism.

因其具有广泛的组织亲和性，腺病毒成为表达和传递治疗基因的主要候选者。

39. It is, therefore, feasible to exploit IL-8 promoter to control the replication of oncolytic adenovirus aiming to achieve more tumor-targeted oncolysis for treating NSCLC.

因此，在非小细胞肺癌中以介白素八调控子控制溶瘤腺病毒应可具有更佳的肿瘤专一性与溶瘤效果。

40. Results: Adeno-X-SSTR2,recombinant adenovirus vector,can infect pancreatic carcinoma cells MIA-PaCa-2 and AsPC-1 efficiently,which both can express SSTR2 mRNA and their protein.

在不同浓度NC-8-12和奥曲肽作用下,未转染SSTR2基因胰腺癌细胞株的Survivin表达量无明显变化(P>0.05),转染了SSTR2基因胰腺癌细胞株的Survivin表达量明显下调(P<0.05);

41. The dispersed pancreas cells were transfected with exogenous gene by adenovirus vector and cationic polymer reagent, respectively.

在细胞分散后对孔鳐胰脏细胞用腺病毒载体和阳高子多聚物进行外源基因的转染。

42. The most effective way to prevent and cure Ebola virus is vaccine. For Ebola virus, the subunit vaccine strategies published hefore have used live vaccine virus vectors, DNA vaccination, and a DNA prime with adenovirus boost strategy.

埃博拉病毒的防治方法中最有效的是疫苗,早期较为常见的是以载体疫苗和DNA疫苗为代表的亚单位疫苗以及用DNA激发配合腺病毒增强疫苗。

43. Gendicine uses an adenovirus as a carrier, or vector, to take tumour-suppressing DNA directly to a tumour.

基因药物通过利用腺病毒作为载体，或称为带菌体，直接携带可抑制肿瘤的DNA接近肿瘤。

44. conditionally replicating adenovirus

增殖型腺病毒

45. Infection of tumor cells with conditionally replicating adenovirus results in tumor-specific replication,subsequent oncolysis and release of the virus progeny.

增殖型腺病毒能在肿瘤细胞中复制并裂解肿瘤细胞,释放出的子代病毒再感染邻近肿瘤细胞直至完全杀灭肿瘤,却不影响正常细胞的功能。

46. replicative oncolyitc adenovirus

增殖性溶瘤腺病毒

47. conditionally replicative adenovirus

增殖腺病毒

48. Reduplication-selective recombinant adenovirus

增殖选择性腺病毒

49. Replication deficient adenovirus

复制缺陷型腺病毒

50. replication-defective adenovirus vector

复制缺陷型腺病毒载体

51. Replication deficient recombinant adenovirus

复制缺陷型重组腺病毒

52. Repilication-deficient adenovirus vascular

复制缺陷性型腺病毒

53. The authors especially analysed manifestations of respiratory syncytial virus, adenovirus and bacterial pneumonia.

对呼吸道合胞病毒肺炎、腺病毒肺炎和细菌肺炎的临床表现进行了分析。

54. The typical adenovirus was observed with electro-microscope by sample of purified NGVEV of DEF cell culture, approximately 70-90 nanometer (nm).

将适应DEF的NGVEV 感染DEF细胞后经超薄切片及电镜观察,可见典型的腺病毒粒子,病毒粒子大小为70-90nm。

55. chimeric adenovirus AdS F11b

嵌合型腺病毒Ad5F11b

56. Experiments on antipyretic detoxification liquid against respiratory syncytial virus and adenovirus were performed with cell culture technique.

应用细胞培养技术,对工艺改进后的清热解毒液进行了抗呼吸道合胞病毒和腺病毒的研究。

57. Keywords PCV2;infection;recombinant;adenovirus;vaccine;PMWS;

感染;PMWS;重组腺病毒;基因工程疫苗;研究;

58. Latent adenovirus infection in chronicobstructivepulmonary disease

慢性阻塞性肺疾病中的腺病毒潜在感染

59. The recombinant adenovirus containing rPB-DR promoter and TK gene has been constructed successfully, and this lays the foundation for the research of gene therapy of prostate cancer .

成功构建出包含rPB DR启动子和TK自杀基因的重组复制缺陷型腺病毒并鉴定正确,可用于下一步前列腺癌基因治疗的研究中。

60. Adenovirus carrying antisense mdr1 RNA can partially reverse the MDR of HepG2/ADM cells and inhibit tumor growth by down-regulating mdr1 mRNA resulting in tumor cell apoptosis.

携带MDR1反义RNA重组腺病毒部分逆转HepG2/ADM的多药耐药,阻止肿瘤生长,下调MDR1转录水平,导致肿瘤细胞凋亡。

61. Adenovirus CNHK600-p53 carrying p53 gene can enhance chemosensitivity of BEL7404 hepatocarcinoma cell line. Gene therapy using adenovirus CNHK600-p53 in combination with chemotherapy may be a new strategy for hepatocarcinoma treatment.

携带p53基因的CNHK600-p53能提高肝癌细胞株BEL-7404对化疗药物的敏感性,CNHK600-p53联合化疗药物治疗可望开辟克服肝癌耐药的新途径。

62. Adenovirus vectors have the characteristics of high transfection efficiency and low cytotoxicity, and they have become most widely used vectors for gene therapy.

摘要腺病毒载体具有高效转染和低细胞毒性的特点，已成为基因治疗研究中应用最广泛的载体之一。

63. Adenovirus as gene transfer vector is characterized by high transfection efficiency, high titer, good stability in target cells and low pathogenicity, and has been widely used in gene therapy.

摘要腺病毒载体是一种非常有效的转基因载体，具有高效率、低致病性、高滴度及不整合入宿主细胞染色体等优点，广泛应用于基因治疗。

64. Method The cultured synovial cells of rheumatoid arthritis were infected by adenovirus containing lacZ reporter gene. Then the expression of lacZ gene were showed by the X gal method and the diagram of expression was drawed.

方法 将含LacZ报告基因腺病毒感染类风湿关节炎滑膜细胞 ,通过X gal显色的方法观察腺病毒感染滑膜细胞后基因的表达情况 ,绘制感染效率曲线。

65. Methods The pAdIL-10 constructed by our laboratory was transferred into HEK 293 cells by lipofectamin for packing, and the recombinant replication-deficient adenovirus, AdIL-10, was finally obtained.

方法 将本实验室自行构建的重组腺病毒质粒pAdIL-10用Lipofectamin包装转染HEK 293细胞，即可获得重组腺病毒AdIL-10。

66. Methods The respiratory syncytial virus (RSV), influenza virus (IFV) A and B, parainfluenza virus (PIV) 1, 2 and 3 and adenovirus (ADV) were detected in 2209 infants with ALRI by direct immunofluorescence method.

方法 采用直接免疫荧光法检测2 2 0 9例急性下呼吸道感染患儿呼吸道诱导痰中脱落纤毛柱状上皮细胞中的呼吸道合胞病毒、流感病毒A型及B型、副流感病毒 1、 2、 3型、腺病毒。

67. Anti adenovirus effect of these extracts were studied by virus sensitivity test in vitro.RESULTS AND CONCLUSION:These extracts have significant effects on anti adenovirus.

方法:通过体外病毒敏感性试验,对不同方法提取的金银花浸膏进行了药效实验。

68. Methods The kidney of SD rats were transfected with CTLA4-Ig gene-recombined adenovirus.

方法以CTLA4-Ig基因重组腺病毒为载体,将CTLA4-Ig基因局部转染入SD大鼠肾脏。

69. Methods:The HIF-dependent recombinant adenovirus Ad-5HRE/hCMVmp-BCD was constructed by DNA recombinant technique. Western blot was used to detect HIF-dependent expression of bacterial cytosine deaminase (BCD).

方法借助DNA重组技术构建HIF依赖性表达的重组腺病毒载体Ad-5HRE/hCMVmp-BCD。

70. The results showed that: adenovirus vector in HEK-293 cells in the packaging successful, the virus appears macrophages spot. 2.

最后用磷酸钙转染法把重组腺病毒载体转染到 HEK-293细胞中包装。

71. This study was to construct dual cancer-specific targeting adenovirus called TD55 to evaluate its security, and construct TD55-TRAIL to explore its antitumor effect.

本研究旨在构建肿瘤特异性的双靶向腺病毒TD55,并研究其安全性;在TD55中插入凋亡基因TRAIL,构建成TD55-TRAIL,研究其杀伤性。

72. replication-conditional adenovirus

条件复制型腺病毒

73. Coxsackie adenovirus receptor

柯萨奇-腺病毒受体

74. Coxsackie and adenovirus receptor;

柯萨奇-腺病毒受体;

75. Keywords Coxsackie adenovirus receptor;Mice;Myocardial diseases;

柯萨奇-腺病毒受体;小鼠;心肌疾病;

76. Coxsackie and adenovirus receptor/CAR

柯萨奇病毒-腺病毒受体

77. coxasckievirus and adenovirus receptor

柯萨奇病毒和腺病毒受体

78. coxsackie adenovirus receptor (CAR)

柯萨奇腺病毒受体

79. Coxsackie Adenovirus Receptor and Viral Myocarditis

柯萨奇腺病毒受体与病毒性心肌炎

80. Keywords EBV;lymphoma;gene therapy;adenovirus;

淋巴瘤;基因治疗;腺病毒;