alloantigen

alloantigen

1. Research Development of Human Platelet Alloantigen Basic and Clinical

人类血小板抗原基础与临床研究进展

2. In vitro studies have shown that they do not induce immune response and can inhibit immune cells involved in alloantigen recognition and elimination.

体外研究显示它们不诱导免疫应答,对识别、清除同种异体抗原的免疫细胞具有抑制作用。

3. Suppression of allo-specific CTL activity in allo-TCV immunized mice; the activity of specific CTL to alloantigen generated by in vitro bulk MLR in TCV group was much lower than that in.

在CML实验里,同种抗原特异TCV免疫小鼠的脾细胞体外诱导同种CTL活性明显受到抑制,CTL 活性十分低下。

4. Pregnancy constitutes a major challenge to the maternal immune system, as it has to tolerate the persistence of paternal alloantigen.

妊娠失败多因母体对胚胎的免疫排斥所致。

5. lymphocyte alloantigen

淋巴细胞异种抗原

6. Results Auto-keratinocytes could inhibit the lympho-proliferation induced by alloantigen.

结果自体角质形成细胞可抑制淋巴细胞对同种异体抗原的增殖。

7. Results showed that 335A remarkably suppressed the transformation of mouse splenocytes stimulated with ConA and alloantigen (MLR). In a dose-dependent profile, the IC 50 was 2.2 and 10ng/ml respectively.

结果表明 ,335 A体外对小鼠脾细胞的增殖反应及混合淋巴细胞反应均呈强烈的抑制作用 ,半数抑制浓度 (IC50 )分别为 2 .2和10 ng/ ml,且是一种特异的 T细胞抑制剂。

8. Serial mixed lymphocyte assays demonstrated suppression of the recipient immune response to the donor antigen after pretreatment, but no additional neuroregenerative effect of donor alloantigen pretreatment.

而混合淋巴细胞检测则表明，预处理后受体对供体抗原的免疫反应被抑制，但供体的同种异体抗原对神经再生无促进作用。

9. Keywords platelet;polymorphism;gene frequency;alloantigen;transfusion;

血小板;多态性;基因频率;同种抗原;输血;

10. platelet specific alloantigen

血小板特异性同种抗原