allopurinol

allopurinol

1. "Twenty of 30 children were normotensive [had normal blood pressure] on allopurinol," he says.

“30名孩子中的20名在服用别嘌呤醇后血压正常，”他说。

2. "When I give allopurinol to adults, there is a list of side effects [I provide to them].

“当我给病人开别嘌呤醇时，我会告诉他一长串的副反应。”

3. "I really don't want this [study] to be taken to suggest that allopurinol is a good alternative for treatment of blood pressure in children or adults," says Daniel I.

“我真的不想这一研究被用来支持把别嘌呤醇作为治疗儿童或成人高血压的一个很好选择，”DanielI.

4. "It's a leap to consider allopurinol an alternative treatment for high blood pressure in teens.

“把别嘌呤醇作为治疗青少年高血压的一个选择，这一想法有点操之过急。”

5. "While most gout patients do well with the drug allopurinol, there is a subset of about 50,000 patients in the U.S. who don't respond to it or who can't tolerate it and who have no real alternatives.

“虽然大多数痛风患者都可以相对安全地使用别嘌呤醇，但在美国有约50000例患者要么使用该药无效、要么有耐药性却别无选择。

6. Two experts who reviewed the study results for WebMD worried, as Feig did, that the results would be over-interpreted and viewed as a reason to use allopurinol in teens.

两名负责为WebMD审阅该研究结果的专家像Feig一样，担心研究结果会被夸大并被用于支持将别嘌呤醇用于治疗青少年高血压。

7. Allopurinol limits the amount of uric acid the body makes.

别剽铃醇可以减少体内尿酸的生成。

8. Allopurinol ;Rattus norvegicus ;Diabetes ;Xanthine Oxidase ;therapeutic aspects ;

别嘌呤醇 ;

9. Poisoning by allopurinol

别嘌呤醇中毒

10. Effects of Allopurinol on Endothelial and Cardiac Function in Patients With Coronary Heart Disease

别嘌呤醇对冠心病患者内皮功能及心功能的影响

11. Effect of Allopurinol on the Function of Blood Vessel Endothelium in Patients with Essential Hypertension Complicating Hyperuricemia

别嘌呤醇对原发性高血压合并高尿酸血症患者血管内皮功能的影响

12. Effects of Allopurinol on Production of Oxygen Free Radicals in Cardiac Valve Replacement

别嘌呤醇对心瓣膜置换手术中氧自由基生成的影响作用

13. allopurinol nucleotide

别嘌呤醇核苷酸

14. allopurinol;heavy drug eruption;pathogenesis;clinic treatment

别嘌呤醇；重型药疹；发病机制；临床对策

15. Keywords allopurinol;oxypurinol;bi-layer osmotic pump;mono-layer osmotic pump;pharmacokinetics;

别嘌醇;氧别嘌醇;双层渗透泵;单层渗透泵;药物动力学;

16. Keywords Allopurinol;Residual formamide;Gas chromatography;

别嘌醇;甲酰胺残留;气相色谱;

17. Keywords allopurinol;drug concentration in plasma;HPLC;human bioequivalence;

别嘌醇;血药浓度;高效液相色谱法;人体生物等效性;

18. Effects of Allopurinol on cardiac function in patients with congestive heart fai lure

别嘌醇对充血性心力衰竭患者心功能的影响

19. allopurinol riboside

别嘌醇核苷

20. An open clinical study of Allopurinol as an add-on therapy for patients with intractable epilepsy

别嘌醇添加治疗难治性癫痫58例疗效观察

21. Allopurinol tablets

别嘌醇片

22. Pharmacokinetics and bioequivalence of sustained-release allopurinol tablets in healthy volunteers

别嘌醇缓释片人体药物动力学与生物等效性研究

23. Transient aplastic anemia associated with allopurinol

别嘌醇致一过性再生障碍性贫血

24. Exfoliative dermatitis due to allopurinol: 2 case reports

别嘌醇致剥脱性皮炎2例

25. allopurinol sodium

别嘌醇钠

26. Keywords allopurinol sodium;related compounds;reversed phase high performance liquid chromatography gradient elution method;

别嘌醇钠;有关物质;高效液相梯度洗脱法;

27. If allopurinol toxicity occurs, options include other xanthine oxidase inhibitors, a uricosuric agent, or allopurinol desensitisation (the latter only in cases of mild rash).

如出现药物毒性，其他选择包括其他黄嘌呤氧化酶抑制剂、促进尿酸排泄药或脱敏疗法（后者仅适于轻度皮疹者）。

28. The effects of nimodipine and allopurinol on the cerebral blood flow and oxygen consumption in dog after complete cerebral ischemia.

尼莫地平、别嘌呤醇对完全性脑缺血后脑血流和氧耗影响的实验研究

29. Keywords Uric acid;Chronic renal disease;Allopurinol;Prospective study;

尿酸;慢性肾病;别嘌呤醇;前瞻性研究;

30. A HPLC method for determination of allopurinol in human plasma for study of human bioequivalence of two tablet formulations was presented.

建立人血浆中别嘌醇的高效液相色谱测定方法 ,用于人体生物等效性研究。

31. HPLC method for determination of allopurinol in human plasma for study of human bioequivalence of two tablet formulations was presented.

建立人血浆中别嘌醇的高效液相色谱测定方法,用于人体生物等效性研究。

32. Keywords Heart failure;Allopurinol;Uric acid;Endothelium;Vasodilatation;

心力衰竭;别嘌呤醇;尿酸;内皮;血管舒张;

33. Effects of allopurinol on vascular endothelial function in patients with chronic heart failure

心衰患者尿酸对血管内皮功能的影响及别嘌呤醇的干预

34. Keywords chronic uratic nephropathy;deficiency of both qi and yin;Yiqi Yangyin Decoction;Allopurinol Tablets;

慢性尿酸性肾病;气阴两虚;益气养阴汤;别嘌呤醇片;

35. "Allopurinol, a xanthine oxidase inhibitor that blocks generation of oxygen-derived free radicals, potentially may prevent post-ERCP pancreatitis.

抑制剂，可以阻断氧气所衍生的自由基，在进行ERCP后，对胰脏炎的发生，具有预防的潜力。

36. Keywords Antipodagrics;Benzbromarone;Allopurinol;Colchicine;Sales sum;Market analysis;

抗痛风药;苯溴马隆;别嘌醇;秋水仙碱;销售金额;市场分析;

37. Keywords Newborn;premature infant;Cerebral anoxia;Cerebral ischemia;brain damage;White matter;Xanthine oxidase;Free radicals;Hydroxyl radicals;Apoptosis;allopurinol;Moderate hypothermia;

新生;早产;脑缺氧;脑缺血;脑损伤;脑白质;黄嘌呤氧化酶;一氧化氮合酶;氧自由基;羟自由基;凋亡;别嘌呤醇;亚低温;

38. Methods Under the guide of the standardized and widespread metabolic evaluation, citrate and allopurinol were administered in 54 patients with uric acid calculi in kidney.

方法:以广泛式代谢评估为指导,使用枸橼酸盐和别嘌呤醇对54例肾尿酸结石病人进行溶石治疗,长期维持用药并结合饮食疗法。

39. Methods retrospective analysis of 9 cases of severe drug eruption by allopurinol was made in detail;

方法对9例别嘌呤醇致重症药疹患者的临床表现、实验室检查、治疗、预后进行回顾性分析。

40. Methods 21 cases of drug eruption caused by allopurinol from Jan 1993 to Dec 2001 in our hospital were retrospectively analyzed.

方法对本院1993年1月至2001年12月间收治的别嘌呤醇所致药疹21例进行临床分析。

41. Methods 724 patients with malignant tumors under the treatment of fluorouracil based chemotherapy were randomized into four groups: A, B, C and D. Patients in group A were treated with allopurinol 0.1gram 3 times a day.

方法将724例接受氟脲嘧啶类为主抗癌药物治疗的患者随机分为A、B、C、D组,A组口服别嘌呤醇片0.1g,3次/d;

42. Methods 82 patients were randomly divided into two groups: the treatment group 1(52 patients treated with "QiLong Fengshi Wan"),the treatment group 2(30 patients treated with allopurinol).

方法将82例患者随机分为两组,中药治疗组52例病人应用自拟中药芪龙风湿丸治疗,对照组30例应用别嘌呤醇治疗。

43. Of interest, when allopurinol was gien, a significant decrease in lipid peroxidation was obsered.

有趣的是，当使用别嘌呤醇时，脂质过氧化程度显著降低。

44. Effects of Oxygen Radicals: on Gut Barrier Function of Chronic Portal Hypertensive Rats and Protective Role of Allopurinol

氧自由基在肝硬化门脉高压大鼠肠粘膜屏障损伤中的作用及别嘌呤醇的保护作用

45. Results Severe drug eruption by allopurinol had four types:erythema multiforme gravis or Steven-Johnson syndrome,epidermal necrolysis and exfoliative dermatitis.

潜伏期长、病情急重、肝肾受累常见、糖皮质激素治疗有效,但病程长、死亡率高。

46. Keywords acute gouty arthritis;Tongxinluo capsule;Allopurinol;Diclofenac;

痛风性关节炎;通心络胶囊;别嘌醇片;扶他林;

47. Objective To analysis and discuss the clinic features of allopurinol hypersensitivity syndrome (AHS).

目的 分析别嘌呤醇超敏综合征 (AHS)的临床特点并进行讨论。

48. AIM: To observe the effects of allopurinol, an activated xanthine oxidase (XO) inhibitor on myocardial contractility and intracellular calcium content of rats with chronic congestive heart failure.

目的:观察活化的黄嘌呤氧化酶抑制剂别嘌呤醇对慢性充血性心力衰竭大鼠心肌收缩力及细胞内钙含量的影响。

49. Objective To comprehend the side effects of allopurinol.

目的了解别嘌呤醇的药物不良反应。

50. Objective To study of the clinical feature of severe drug eruption by allopurinol.

目的探讨别嘌呤醇致重症药疹的临床特点。

51. Treatment with rapid fluid infusion, hemodialysis, and allopurinol resulted in prompt and complete recovery of renal function.

经过静脉输液补充、血液透析、及降尿酸药物之使用，其肾脏功能回覆到正常值。

52. Conclusion The principals of corticosteroid therapy in severe drug eruption by allopurinol are early using, sufficient dose, enough duration and gradually reduction.

结论别嘌呤醇致重症药疹应用皮质类固醇激素治疗时宜早期、足量、足疗程、缓慢减量。

53. Conclusions TLS can be effectively controlled by early recognition and administration of allopurinol therapy and alkalinization of urine.

结论早期诊断并及时给予别嘌呤醇及静脉碱化利尿是治疗TLS的关键。

54. Keywords Drug hypersensitivity syndrome;Allopurinol;

药物超敏综合征;别嘌醇;

55. Keywords flavonoids from fruit residues of vaccinium vitisidaea L.（FFV）;hyperuricemia;xanthine oxidase （XO）;serum uric acid;allopurinol（AP）;

越桔果渣黄酮;高尿酸血症;黄嘌呤氧化酶;血清尿酸;别嘌醇;

56. Keywords Allopurinol;Serere Drug Eruption;Clinical Analysis.;

重症药疹;别嘌呤醇;

57. Improvement of myocardial contractility of rats with heart failure by long-term oral treatment of allopurinol

长期口服别嘌呤醇改善心力衰竭大鼠的心肌收缩力

58. In the intermission, patients in TCDtreated group were given Yinlian Gout Granule, and patients in WMtreated group were given benzbromarone or allopurinol.

间歇期中药组予茵连痛风颗粒，西药组予苯溴马隆片或别嘌呤醇片；

59. Keywords hyperuricemia;Allopurinol;congestive heart failure;cardiac function;nitric oxide;reactive oxygen species;

高尿酸血症;别嘌醇;心力衰竭;充血性;心功能;一氧化氮;活性氧族;

60. Keywords hyperuricaemia;benzbromarone;small dosage;allopurinol;

高尿酸血症;小剂量;立加利仙;别嘌醇;

61. Keywords hyperuricemia;tongfengnin;little mouse;allopurinol;binghuangshu;saleratus;

高尿酸血症;痛风宁;别嘌呤醇;丙磺舒;小苏打;小鼠;

62. Determination of related substances by reversed phase high performance liquid chromatography gradient elution in allopurinol sodium for injection

高效液相梯度洗脱法测定注射用别嘌醇钠中的有关物质

63. Allopurinol, a XO inhibitor can improve the unbalanced distribution of calcium in heart failure to make the [Ca2+]i recover to the normal level and enhance the myocardial contractility.

黄嘌呤氧化酶抑制剂别嘌呤醇能改善心衰心肌钙分布的不平衡状态,使细胞内钙水平恢复接近正常水平,增加心肌的收缩力。