bioavailability

bioavailability

1. Conclusion: To make coprecipitate with PVP as warrier is one of the ways in order to enhance bioavailability of the difficult soluble drugs.

26%。结论:将难溶性药物制成以亲水性高分子材料为载体的共沉淀物,对于提高难溶性药物的生物利用度是有效的方法之一。

2. APIC would be expected to become iron-supplementary nutrition with higher bioavailability.

APIC有望发展成为高生物利用度的营养型补铁剂。

3. AUC is the most reliable measure of bioavailability.

AUC是最可靠的生物利用度指标。

4. The result of bioavailability in beagle dog showed that the AUC of 4ac-PLA-NP was 8 times more than that of free 4ac.

BCaglc犬体内的药代动力学实验结果表明，静注4ac一PLA.

5. AGING AND BIOAVAILABILITY OF DDTs IN SOIL

DDTs在土壤中的老化规律及生物有效性

6. Oral bioavailability of ICS such as fluticasone, ciclesonide and mometasone is minimal, as a result of their essentially complete first-pass metabolism in the liver.

ICS（如氟替卡松、环索奈德和莫美他松）的口服生物利用度最小，因为这些药物主要经过肝脏的首过代谢消除。

7. JIANG Xia,JING Xin,GAO Xue-sheng,et al.Advances in studies on the effect of surfactant on bioavailability of polycylcic aromatic hydrocarbons(PAHs)in soil[J].Chin J Appl Ecol,2002,13(9):1179-1186.

[3]姜霞,井欣,高学晟,等.表面活性剂对土壤中多环芳烃生物有效性影响的研究进展[J].应用生态学报,2002,13(9):1179-1186.

8. Jiang ZQ,Jiang XG ,Xi NZ,et al.Determination of loratadine in human plasma by a sensitive HPLC method and evaluation of its bioavailability[J].Zhongguo Yaoxue Zazhi (Chin Pharm J),1999,34(11):757-759.

[4]江志强,蒋新国,奚念朱,等.氯雷他定血药浓度HPLC测定方法建立和生物利用度[J].中国药学杂志,1999,34(11):757-759.

9. Phase I pharmacokinetic single dose study in human volunteers showed that MIV-210 has a high oral bioavailability and no side effects were observed.

一期临床药物单剂量实验中,志愿者显示MIV-210有很高的口服利用率,没有发现副作用。

10. Relative bioavailability of different carbamazepine tablets in rabbits

不同厂家卡马西平片在家兔体内生物利用度

11. Compared with the Neoral microemulsion,the relative bioavailability of CyA was 94.8%,115.2%,113.6% and 132.5% for CyA-E100,CyA-L100,CyA-L100-55 and CyA-S100 nanoparticles respectively.

与Neoral微乳相比, CyA E100,CyA L100,CyA L100 55和CyA S100纳米粒的相对生物利用度分别为94.8%,115.2%,113.6%和 132.5%。

12. The relative bioavailability of CyA HP50 and CyA HP55 nanoparticles calculated by the AUC 0-72 were 82 3% and 119 6%, bioequivalent to the reference of Neoral.

与Neoral相比 ,CyA HP5 0NP与CyA HP5 5NP的相对生物利用度分别为 82 3%和 1 1 9 6% ,均无显著性差异 ;

13. More factors can affect bioavailability when absorption is slow or incomplete than when it is rapid and complete, so slow or incomplete absorption often leads to variable therapeutic responses.

与吸收慢和不完全的药物相比，吸收迅速而完全的药物的生物利用度影响因素更多。因此，吸收缓慢或不完全常常导致治疗学效应的不同。

14. Abstract: The bioavailability of heavy metals (HM) in soils and sediments could be evaluated by single chemical extraction methods.

中文摘要: 土壤和沉积物中重金属被植物吸收利用可通过单一化学萃取方法评估。

15. In order to improve the drug quality,to establish dissolution test for indissolvable drug granules should be strengthened to improve such kind of the products' bioavailability and clinical efficacy.

为切实地提高药品质量,建议加强水难溶性药物颗粒剂的质控标准,拟定溶出度检查项,以提高改类产品的生物利用度和临床疗效。

16. The concept of bioavailabiblity of trace metals in anaerobic wastewater treatment system is introduced and the factors affecting the bioavailability are analyzed.

介绍了废水厌氧处理系统中微量金属营养元素生物有效度的概念,分析了影响微量金属营养元素生物有效度的诸多因素。

17. The concept of ecological geochemistry and properties such as bioavailability,residues in environmental media and long-distance migration of organochlorine pesticides are introduced in this paper.

介绍了生态地球化学的概念和有机氯农药的生物有效性、环境介质中的残留、远距离迁移等性质。

18. This has met with limited success according to Gillisen and Nowak(8).Aerosolized GSH has a low half-life and NAC has a bioavailability of about 10%(8).

但（研究8）发现使用效果有限，微粒化谷胱甘肽的半衰期很短而NAC的生物可用率只有10%。

19. Low bioavailability is most common with oral dosage forms of poorly water-soluble, slowly a orbed drugs.

低生物利用度最常见于水溶性差、吸收慢的药物的口服剂型。

20. This review briefly discusses dendrimers used as a novel macromolecular vector for safety,high bioavailability and low mammalian toxicity,and their potential appli...

作为一种新型非生物载体,其安全、高效、无毒,在药物输送、基因转移和医疗诊断等方面具有广阔的应用前景。

21. As a new formulation technology, it has considerable significance not only in increasing the bioavailability of the poor solubility pesticides, but also in raising the efficacy.

作为一种新的制剂技术，纳米混悬剂在提高低溶解度农药的生物利用度和药效等方面具有重要意义。

22. Bioavailability study of CLM tablet in normal subjects

克拉霉素片剂的生物利用度研究

23. Relative bioavailability and pharmacokinetics of clarithromycin in healthy volunteers. ......

克拉霉素；药动学；生物利用度；生物等效性

24. Keywords TFu;Liposomes;Paticle size;Bioavailability;

关键词托氟啶;脂质体;粒径;生物利用度;

25. Keywords sumatriptan;pharmacokinetics;bioavailability;HPLC-MS;

关键词舒马普坦;药物动力学;生物利用度;HPLC-MS;

26. The bioavailability of the injection reaches as high as 100%, which is higher than ofloxacin and Ciprofloxacin.

其在体内具有完全的生物利用度，达到100%，高于氧氟沙星，环丙沙星等同类品种。

27. Relative bioavailability of lorazepam tablets in healthy volunteers

劳拉西泮片在健康人体中的相对生物利用度

28. The microemulsion and nano-suspension of drug have superior suspensibility, dispersibility and bioavailability.

医药微乳剂和纳米悬浮剂可显著改善药物的悬浮性和分散性,提高生物利用度。

29. Bioavailability determinations based on the peak plasma concentration can be misleading, because drug elimination begins as soon as the drug enters the bloodstream.

单靠峰时血浆浓度来确定生物利用度会导致误解，因为药物一进入血流就会开始药物消除。

30. The presence of trace metals is not equal to the bioavailability of trace metals in the system.

厌氧生物处理系统存在微量金属营养元素并不等于存在微量金属营养元素生物有效度;

31. English: Whether the decrease in bioavailability is of such a magnitude to cause a reduction in the action of digoxin is unclear.

原译:这种条件下的生物利用度降低是否引起地高辛作用的减退尚不清楚。

32. Double stable isotope technique, a safety and accurate method todetermine calcium absorption in humans, has been recently applied to evaluatecalcium bioavailability.

双稳定核素示踪技术是一种可以安全、准确地测定人体钙吸收率的方法,近年被逐渐用于评价钙剂生物利用度。

33. Bioavailability and Bioequivalence Studies for Orally Administered Drug Products-General Considerations.

口服剂型的生物利用度和生物等效性研究-总体考虑。

34. When taken orally, bisphosphonates are poorly absorbed and have low bioavailability.

口服双磷酸盐的吸收率及生物利用度非常低。

35. Oral bioadhesive particulate system for drug delivery can delay the drug staying on epthical cell and improve the bioavailability of drug by using bioadhesive polymers.

口服生物黏附微粒释药系统是通过黏附聚合物的使用,使各种药物存留在上皮细胞膜上的时间延长从而提高生物利用度。

36. Intestinal absorption of oral administration are the important means to effect bioavailability.

口服药物在肠道中的吸收是决定药物生物利用度的重要因素。

37. controlled drug bioavailability

可控药物生物利用度

38. At the same time.the contribution to pharmaceutics of M-cell is reviewed.After some microparticle drug delivery systems were modified,they can be transported by M-cell to enhance the bioavailability.

同时,综述了近几年M细胞在药剂学方面的利用,一些微粒给药系统通过凝集素修饰以后,通过M细胞转运提高口服生物利用度。

39. Besides, considering to developing uses of calcium propionate, the bioavailability and medicinal dynamics were studied and prospect of the application o...

同时，为了拓宽其应用范围，对两酸钙用做钙质强化剂的生物利用度和药物动力学也作了初步研究。

40. The monitoring of C1 can provide a rapid in vivo screening method to study the bioavailability of cyclosporin fomulations and drug-cyclosporin interactions.

因此以此单点监测模式应可提供作为环孢灵制剂之生体可用率或环孢灵与其他药物交互作用之快速体内预试验。

41. Therefore, screening the specific bacterial genus or strains and using them as additive of glycosides should remove individual difference in bioavailability of glycosides.

因此，筛选出具有生物转化苷类中药活性的特异性肠道细菌菌属和菌株，将之与苷类中药同时摄入，将有助于消除苷类中药在人群中应用的个体差异。

42. The disolution amount of R in RSD was 88% more than that of untreated R in imitated gastric jules. The bioavailability of RSD was 21.8% more than that of untreated R in human body.

固体分散物2小时的体外溶出量和人体生物利用度分别较原药提高了88%和21.8%。

43. Solid lipid nanoparticles is a new drug delivery system, which can enhance the bioavailability of poorly soluble drugs.

固体脂质纳米粒作为一种新型给药系统,可以提高难溶性药物生物利用度。

44. Therelative bioavailability of Chinese oral GsA was 91.15%.

国产口服液的相对生物利用度为91.15%。

45. Transformation and bioavailability of selenium in soil depends, to a certain extent, on the humification processes.

土壤-植物系统中硒的小循环中,环境腐植酸物质对土壤硒的环境行为和生物有效性产生了显著影响。

46. Keywords soil;heavy metals;bioavailability;oil pollution;

土壤;重金属;生物有效性;油污染;

47. Keywords soil;lead;speciation;bioavailability;Tongling City;

土壤;铅;形态;生物有效性;铜陵市;

48. Keywords soils;cadmium;speciation;bioavailability;Tongling city;

土壤;镉;形态;生物有效性;铜陵市;

49. The mobility, the bioavailability and the toxicity of heavy metals in the soil depend on their specific chemical forms and on their binding state.

土壤中重金属的赋存形态决定其在土壤中的迁移性、生物可利用性以及毒性。

50. Keywords Soil volatile mercury;Bioavailability;Humic acids.;

土壤挥发汞;生物活性;腐殖酸;

51. When solvation or hydration affects bioavailability, appropriate manufacturing and control procedures should be established.

在溶剂化或水合作用影响生物利用度时，应建立合适的制造和控制方法。

52. REEs in surface of soil column with short-term pollution had great bioavailability, while the bioavailability of REEs in the soil column with long-term pollution increased unde...

在短期污染土柱的表层,稀土元素有较高的生物可利用性;在长期污染土柱中,稀土元素的生物可利用性也增加。

53. In part I,we reported that the repetitive administration of Shaoyao-Gancao-Tang(SGT)increased the bioavailability of glycyrrhizin(GL)in SGT.

在第I部分中 ,已经报告了芍药甘草汤 (SGT)的连续给药提高了SGT中甘草酸 (glycyrrhizin,GL)的生物利用度。

54. Polymorphism, solvation, or particle size has an important effect on bioavailability.

多态现象、溶剂化作用或粒度大小对生物利用度有重要影响。

55. Many studies show that 4-oxo-dihydroquinolines have good oral bioavailability and plasma clearance,and they suppress both the DNA polymerase of HSV and virus replication in the cells.

多项研究表明,4-氧代二氢喹啉类有良好的口服利用率及中等程度的血浆清除率,不仅对核苷酸聚合酶产生抑制,还可以抑制细胞内的病毒复制。

56. Both the macrobenthos density and the number of species were found to be higher in the outer shelf region where the sediment contained high bioavail able protein.

大型底栖动物之密度及种类丰富度以陆棚外侧之可利用蛋白质含量的地区最高。

57. STUDY ON ZINC BIOAVAILABILITY OF NATURAL AND BROKEN MASSON PINE POLLEN

天然和破壁松花粉中锌生物利用度的研究

58. Relative bioavailability of cefaclor chewable tablet in human

头孢克洛咀嚼片的人体相对生物利用度

59. Relative bioavailability of oxaprozin dispersible tablet in healthy volunteers

奥沙普秦分散片的人体相对生物利用度

60. The research verified that Puerarin pill"s procedure is stable and the quality is controlable.Comparing with the other oarl solid preparation,Puerarin pill have fast reaction and high bioavailability.

实验证明葛根素滴丸工艺稳定，质量可控，与其它同类口服固体制剂相比，具有速效、生物利用度高的特点。

61. It is necessary to determine the bioavailability of trace metals in the system.

对厌氧生物处理系统进行微量金属营养元素生物有效度的检定是非常必要的;

62. For drugs excreted primarily unchanged in urine, bioavailability can be estimated by measuring the total amount of drug excreted after a single dose.

对那些以原形经尿排出为主的药物而言，其生物利用度可以通过测量单次用药后尿药总量来评估。

63. RELATIVE BIOAVAILABILITY OF ACETAMINOPHEN DROPS

小儿用扑热息痛滴剂的相对生物利用度研究

64. It is complex that the evaluation of nutritional quality of Wheat and wheat foods ranged from the nutrients content to assays for bioavailability of nutrients.

小麦、面粉以及面制食品的营养品质对人们身体健康的影响不容忽视。

65. Whether the decrease in bioavailability is of such a magnitude to cause a reduction in the action of digoxin is unclear.

尚不清楚生物利用度的降低，是否达到能减弱地高辛作用的程度。

66. The paper reviews the mechanism and application of SLN for enhancing the bioavailability of poorly soluble drugs.

就固体脂质纳米粒提高难溶性药物生物利用度的机理及应用作一介绍。

67. The pharmacokinetic profile of Lev closely approximates the ideal characteristics expected of an antiepileptic drug, with good bioavailability, linear and time-invariant kinetics, minimal protein binding, and least metabolism.

左乙拉西坦几乎具备了较好的抗癫痫药物的所有药动学特性：生物利用度高、线性曲线、低蛋白结合率、无肝酶诱导作用。

68. Age, sex, activity, genetic phenotype, stre , disease （eg, achlorhydria, mala orption syndromes）, or previous GI surgery can affect drug bioavailability.

年龄、性别、活动情况、遗传表型、应激、疾病（如胃酸缺乏,营养不良综合征）或既往胃肠手术等均能影响药物的生物利用度。

69. The DPG test is recom-mended for the estimation of relative bioavailability of nitroglycerin.

建议用手指血流阻抗法测定该制剂的相对生物利用度。

70. Development of Bioavailability Program Package

开发生物利用度研究的数据处理通用程序

71. CaCO3 was the main factor influencing the soil Se bioavailability; and the contents of silt grains, organic matters and clay grains were the next.

影响土壤Se生物有效性的主要因子是CaCO3,其次是粉粒、有机质、黏粒含量.

72. Biochelation plays an important role in the bioavailability of trace metals.

微生物的螯合作用对微量金属营养元素生物有效度起非常重要的作用;

73. Microdialysis can be used to study bioavailability and bioequivalence of different preparation.

微透析技术可用于制剂的生物利用度及生物等效性研究。

74. Influence of Suspended Solids on Bioavailability of Copper in Yellow River

悬浮颗粒物对黄河铜的生物有效性影响的研究

75. RELATIVE BIOAVAILABILITY OF ACETAMINOPHEN MASTICATION TABLET

扑热息痛咀嚼片的相对生物利用度研究

76. Peptidomimetics are molecules that mimic the functions of peptides and proteins but have better biostability and bioavailability than natural peptides and proteins.

拟肽研究是为了得到既具有稳定二级结构又具有生物活性和稳定性的非天然多肽，从而用于模拟天然多肽的结构与功能。

77. The transportability through BBB and bioavailability of the inhibitors will be the focus by the systemafic bioassay in vivo.

指出以后的工作重点是进行系统深入的生物体内评价，解决药物透过血脑屏障和生物利用度等问题。

78. Based on this experiment ,contrasting the commercial pills with the refe-rence preparation ,the bioavailability of Xiaohuoluo Pills was studied.

据此，以参比制剂与市售制剂作对比，研究小活络丸的生物利用度。

79. Statistics indicated that bioavailability of Zirong comprehensive biotherapy is 15 times higher than that of traditional apitherapy.

据统计,梓榕综合生物疗法比传统蜂疗方法的生物利用度高出15倍。

80. Ectomycorrhizae evidently decreased bioavailability of heavy metal in the rhizosphere, and alleviated the damage of heavy metal to its host plant.

接种菌根显著降低根际重金属的生物有效性，缓解重金属对寄主植物的毒害作用。