ctol

ctol

1. CTOL maybe play protective role in postoperative intestinal adhension by modulating the activity of fibrinolytic system.

CTOL可能是通过调节机体的纤溶系统以达到防治术后肠粘连的作用。

2. Different dosage of CTOL produced protective effects on the postoperative intestinal adhension accompanied by significant enhancement of t-PA activity and pronounced decreasement of PAI activity.

CTOL各剂量组对兔术后肠粘连有明显的预防作用,并使其血中t-PA活性增高,PAI显著下降。

3. The blood samples of CTOL medium dosage and model control group were collected on the 1st, 3rd, 5th, 7th, 9th day after surgery ; Nine rats were killed after their blood was drawn at different times from each group.

常通中剂量组与模型对照组于术后第1、3、5、7、9天采血,每组每个时间点各取血9只大鼠,并处死。

4. Group 1 and group 2 were orally fed with distilled water (20ml/kg), and group 3 to 6 with Simo Decoction 10ml/kg and CTOL in doses of 2.15g/kg, 4.30g/kg and 8.60g/kg respectively.

常通口服液低、中、高剂量组分别按2.15、4.30、8.60g/kg剂量灌胃给药。 术后第3天兔耳缘静脉取血,测定血浆中组织型纤溶酶原激活物(tPA)及其抑制因子(PAI1)活性;

5. CTOL could prevent postoperative intestinal adhesion formation.

常通口服液能够预防术后肠粘连形成。

6. CTOL could evidently reduce the severity of postoperative adhesions and increase plasma tPA activity and inhibit plasma PAI-1 activity.

常通口服液能明显减轻肠粘连的程度,增加肠粘连兔血浆中tPA活性,而抑制PAI1活性。

7. Methods Fifty-four male Sprague-Dawley rats were randomized into 6 equal groups, namely the normal control, model, Simo decoction (SMD) groups and three CTOL groups of low, moderate, and high doses, respectively.

方法选用SD 雄性大鼠,随机分为6 组:正常对照组、模型对照组、四磨汤组及常通口服液低、中、高剂量组。

8. Methods Sprague-Dawley (SD) male rats were randomly divided into six groups: normal control, no treatment control, Simo Oral Liquid (SOL) group, and CTOL group (minimal, medium and maximal dosages).

方法选用SD雄性大鼠,随机分为6组:正常对照组、模型对照组、四磨汤组及常通口服液低、中、高剂量组。

9. Objective: To observe the effect of Changtong Oral Liquid ( CTOL) on the fibrinolytic activity of rabbits with experimental intestinal adhension.

目的:观察常通口服液(CTOL)对实验性肠粘连兔纤溶活性的影响。

10. OBJECTIVE To develop a method for separating and purifying the two main metabolites of tolbutamide, carboxytolbutamide (CTOL) and hydroxytolbutamide (OTOL), from human urine, then identify the production and determine its purity.

目的研究从生物体液(尿液)中分离纯化甲苯磺丁脲的两个主要代谢物羟基甲苯磺丁脲(OTOL)和羧基甲苯磺丁脲(CTOL)的方法,并对所得的产物进行鉴定和含量测定。

11. Results and Conclusion CTOL evidently reduced the severity of postoperative adhesion and decreased WBC count and plasma FIB level, suggesting the efficacy of CTOL in inhibiting the formation of postoperative intestinal adhesion.

结果常通口服液能明显减轻肠粘连程度,降低大鼠血浆中WBC计数及FIB浓度。 结论常通口服液能够预防腹腔术后肠粘连形成。

12. Compared with controls and vitamin E groups,P<0.05.Conclusion:CTOL can exert evidently effect on the postoperative intestinal adhesion,which prevailed over that by vitamin E.

结论:常通日服液对兔术后肠粘连有显著的预防作用,疗效明显忧于维生素E。

13. conventional take-off and landing [CTOL]

通常起降

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