dynein

dynein

1. Keywords dynamitin;ATPase;dynactin;dynein;microtubules;

ATP酶;动力蛋白激活蛋白;动力蛋白;微管;

2. "One of the unknowns about dynein was that the molecular site where chemical energy is initially released from ATP is very far away from where the mechanical force occurs.

Dokholyan博士说：“动力蛋白将三磷酸腺苷（ATP，细胞的主要能源）转化为机械力，但因为科学家缺乏对动力蛋白结构的全面而详细的了解，所以对转化的机制基本上不了解。

3. To investigate the Pak1 related factors, we used the yeast two-hybrid system to screen a human brain cDNA library, and identified dynein light chain 1(DLC1) as an interacting partner of Pak1.

为了进一步研究和Pak1相关的调节分子，我们用Pak1为诱饵通过酵母双杂交系统筛选了人的胎脑cDNA文库。

4. Dynein also helps force apart chromosomes during cell division.

以及在细胞分裂中，提供了机械能协助染色体的分离。”

5. Dynein ATPase

动力蛋白ATP酶

6. dynein ATPase/TU

动力蛋白ATP酶/治疗应用

7. dynein arm

动力蛋白臂

8. Screening and identification of a novel gene encoding for the dynein light chain in adult worms of Schistosoma japonicum

日本血吸虫肌动蛋白轻链基因的获得和分析

9. Mechanoenzymes such as myosin, dynein, and kinesin interact with the cytoskeletal filaments and tubules to generate forces that cause movements.

机械酶，例如，肌球蛋白，动力蛋白，驱动蛋白与微丝，微管相互作用产生动力而引起细胞运动。

10. Cytoplasmic dynein

胞质动力蛋白

11. While the research offers no immediate application to human disease, the authors noted that mutations of dynein have been implicated in some neurodegenerative and kidney disorders.

虽然研究结果不能马上用于临床，但作者提到动力蛋白突变与一些神经退变及肾脏病有关。