gyrase

gyrase

1. DNA gyrase

DNA解旋酶, DNA回旋酶, DNA旋转酶

2. The authors confirm their findings by showing that chemical or genetic preention of gyrase inhibitor-induced oxidatie damage protects from the bactericidal action of quinolone antibiotics.

使用化学或基因学的方法防止回旋酶抑制剂诱导的氧化损伤，即可对喹诺酮类抗生素的杀菌作用产生保护作用，研究者们由此证实了他们的发现。

3. Antibiotics such as ciprofloxacin can specifically target an essential enzyme called DNA gyrase in bacteria.

像环丙沙星这样的抗生素可以特别的针对细菌中一种基础的叫做DNA促旋酶的酶。

4. Onodera Y,Okuda J,Tanaka M,et al.Inhibitory activities of quinolones against DNA gyrase and topoisomerase IV of enterococcus faecalis[J].Antimicrob Agents Chemother,2002,46(6):1800.

刘志远许淑珍马纪平.肠球菌庆大霉素高水平耐药机理的研究进展[J].中华检验医学杂志,2004,27(4):266-268,.

5. Construction and Identification of Prokaryotic Expression Vector Bearing the Mutant Gyrase A gene From Mycobacterium Tuberculosis

基因原核表达载体的构建与鉴定

6. Mutation in DNA Gyrase A of Escherichia coli Resistante to Quinolone Antibiotics

大肠埃希菌耐喹诺酮类药物回旋酶基因突变的研究

7. If the bacterium did not protect gyrase, the antibiotic would link to the protein, impede normal replication and cause breaks in DNA that would lead to the bacterial cell's death.

旋转酶是DNA复制时不可或缺的酵素，当它与抗生素结合时，细菌复制过程就会受影响，使得DNA断裂，最后导致细菌细胞死亡。

8. Keywords Mycobacterium tuberculosis;Gyrase;DNA;Interaction;

结核分枝杆菌;螺旋酶;DNA;相互作用;

9. DNA gyrase gyrA mutation in quinolone-resistant clinical isolates of Pseudomonas aeruginosa

耐氟喹诺酮类铜绿假单胞菌的gyrA基因突变研究

10. Nucleotide sequence of DNA gyrase gyrA gene of fluoroquinolones-resistant salmonella isolated from chickens

耐氟喹诺酮类鸡源性沙门氏菌DNA旋转酶gyrA基因序列分析

11. reverse gyrase

逆促旋酶