hematopoietic

hematopoietic

1. Grade 1 or 2 hematopoietic tox icity was observed in 58% of patients and grade 3 in 8%.

1 +2级急性骨髓抑制发生率为 58% ,3级为 8%。

2. In July, with the resumption of the post-IPO shares issued one after another, the capital market to restore hematopoietic function.

7月份,随着IPO重启后新股接二连三地发行,资本市场的造血功能得以恢复。

3. HPP-CFC, detected first at early somite stages (E8.25) in mouse yolk sac and ES cells-derived EBs, is the earliest multipotential hematopoietic precursors that can be cultured in vitro in the absence of stromal cells.

80% Smad5-/-HPP-CFC能产生次级HPP-Mix,而仅有20%的野生型HPP-CFC能产生此类集落。 Smad5-/-HPP-CFC的细胞表型和分子表型是吻合的。

4. CD24 is a small,heavily glycosylated cell surface protein that is expressed in a variety of hematopoietic cells and neurocytes thereby playing a variety of important roles.

CD24是一种低分子量高度糖基化膜糖蛋白,主要表达在大多造血细胞和脑组织,发挥重要功能。

5. CD38 is a type II transmembrane glycoprotein with complicated and distinct enzyme activity,and is generally expressed hematopoietic cell and nonhematopoietic cells.

CD38分子是单链II型跨膜糖蛋白,广泛表达于造血细胞及非造血细胞系,具有许多复杂而又独特的生物学特性及功能。

6. CD44 is a trans-membrane glycoprotein widely expressed on many kinds of cell from epithelial,mesenchymal,hematopoietic and mesodermal tissues.

CD44是属于黏附因子家族的跨膜糖蛋白。它广泛表达于多种内皮细胞、间充质细胞、造血干细胞及中胚层来源的细胞和组织。

7. The infection of EBV has direct or indirect ef fection to some cancer, especially to the cancer of lymphatic hematopoietic system.

EB病毒感染对某些肿瘤,尤其是淋巴造血系统肿瘤的发生有着间接或直接的作用。

8. Transcription factors GATA are important regulating factors of hematopoietic system.

GATA转录因子是造血系统重要的调控因子。

9. As a part of bone marrow stromal cells, MSC is the main cell in hematopoietic microenvironments and plays the important role in hematopoietic regulation.

MSC作为骨髓基质细胞的一部分,构成了造血微环境的主要细胞,在造血调控中发挥着重要的作用。

10. The chimeric oncogene BCR/ABL and Ph chromosome,two hall marks of CML,were detected in CML derived MSCs,normal adult MSCs,CML derived hematopoietic cells and K562 cells.

RT-PCR检测CML特异性表达的BCR/ABL基因; 对正常人、CML患者的骨髓间质干细胞进行染色体分析。

11. TPO can stimulate hematopoietic recovery after radiation injury.TPO may have widespread use in such areas as hematopoietic stem cell transplantation, platelets collection and separation.

TPO可促进辐射损伤后的造血重建,有可能解决急性放射病中血小板恢复滞后的问题。

12. The life of a T cell, and all other blood cells, begins in the bone marrow as a hematopoietic stem cell (HSC).

T细胞和其他任何血细胞的生命史开始于骨髓中的造血干细胞(HSC),造血干细胞具有生成血液中各种细胞的潜能。

13. These demonstrated that the feature of hematopoietic cell (CD34+ cell) obtained from BM and UCB was different.

一1,在体外只能能获得极少的贴壁细胞,提示骨髓造血细胞与脐血造血细胞(CD34+细胞)的性质不同。

14. Two important cell signal pathways, JAK-STAT pathway and MAPK pathway, transfer the signals between regulators and hematopoietic relative genes.

两条主要的细胞信号转导通路,JAK-STAT通路和MAPK通路,介导调节调节因子对造血相关基因的活性调控。

15. The traditional Chinese drugs can promote the proliferation of hematopoietic cells and improve the immune function of the body.

中药具有促进造血干细胞增殖,改善免疫功能等作用。

16. For the molecular diagnosis of this syndrome, it is therefore important to sequence DNA from bone marrow cells, or, preferably, from indiidual clonogenic hematopoietic colonies.

为了此类症状的分子学确诊,确定骨髓细胞的DNA序列,或者说确定的克隆原造血细胞的DNA序列,变得很重要。

17. Hematopoietic cells hae been implicated in the ectopic skeletogenesis of fibrodysplasia ossificans progressia, and their replacement has been postulated as a possible cure.

人们认为其异位骨化与造血细胞有关,并认为造血细胞置换可以治愈本病。

18. HIM is the soil of orientation, proliferation, differentiation and development of HSC, of which hematopoietic stromal cell is an important component.

人脐血中是否存在造血基质细胞及其生物学特点如何,脐血基质细胞能否在体外有效扩增,国内外相关的系统性研究较少。

19. What is Hematopoietic stem cell?

什么是造血干细胞?

20. The pathological diagnosis is adrenal myelolipoma since the tumor contained mature adipose tissue in combination with hematopoietic components.

从切除的标本可以发现,有很丰富的成熟脂肪组织,并有造血组织;

21. They found that knocking out the gene in fetal mice whose hematopoietic systems had already formed caused hematopoietic stem cells to disappear.

他们发现击昏已经形成造血系统的胚胎小鼠的基因会引起造血干细胞的消失。

22. The key of this method is to kill residuary leukemia cells, at the same time reserve normal hematopoietic stem cells as far as possible.

体外净化的关键是尽可能地杀灭残存的白血病细胞,同时尽量保存正常的造血干细胞,光动力疗法(Photodynamic therapy, PDT)为此提供了可能。

23. Under this framework, cord blood hematopoietic stem/progenitor cells from unrelated donors are regulated as both HCT/P and as biologic drugs subject to licensure.

依照这一框架,脐带血干细胞既是HCT/P也属生物药物。

24. Erythropoietin (EPO) has been viewed traditionally as a hematopoietic cytokine produced by the fetal liver and adult kidney in response to hypoxia.

促红细胞生成素(EPO)传统上被认为是由胎儿肝脏和成人肾脏对缺血起反应的造血因子。

25. Erythropoietin(EPO) is known as a classical hematopoietic growth factor of cells,which has been used to treat anemia caused by different reasons.

促红细胞生成素(EPO)是一种造血细胞生长因子,以往主要用于治疗多种原因所致的贫血。

26. As a traditionally hematopoietic factor,Erythropoietin(EPO)has other important biologic effects besides hematogenesis.

促红细胞生成素作为一种传统意义上的造血生长因子,有着造血作用以外的重要生物学作用。

27. Thrombopoietin (TPO) is the primary regulator of megakaryocytopoiesis.Recent studies show that there is close relationship between TPO and hematopoietic stem cell.

促血小板生成素)是巨核系造血的主要刺激因子,近年的研究表明,TPO与造血干细胞之间存在密切联系。

28. Hematopoietic elements in this bone marrow biopsy are markedly reduced.This is a case of aplastic anemia.Of course, besides, RBC's the platelets and granulocytes will often be diminished.

再生障碍性贫血骨髓活检可见造血成分明显减少,除此之外,网织红细胞和粒细胞通常减少。

29. Spsikkelman A, de wolfJT, Vellenga E. The application of hematopoietic growth factors in drug-induced a granulocytosis: a review of 70 cases [J] .leukemia 1994, 8 (12): 2031.

刘跃,丁训杰.重组人粒系细胞集落刺激因子临床应用进展[J].临床血液学杂志,1998,11(4):179.

30. Skin and its appendages received most impairment from carbamazepine-induced adverse reactions(representing 35.3%),followed by general impairment of the body and impairment of the blood & hematopoietic system.

卡马西平不良反应以皮肤及附件损害最多(占35.3%),其次为全身性损害及血液系统损害;

31. Hematopoietic form of acute radiation sickness

又称造血型急性放射病

32. It can effectively supplement the hematopoietic growth factors and immnuefactors in the human body, strengthen the sanguifacient function and provide prevention and cure all kinds of anemia.

可有效地补充人体的造血生长因子和免疫因子,增强人体的造血机能,防治各种贫血病。

33. The number of CFU Mix and HPP CFC generated from the culture system containing hDll 1 ext was 1.5 times of that from the control. In conclusion, the recombinant hDll 1 ext promotes the expansion of primitive hematopoietic progenitors.

含hDll 1ext组中CFU Mix和HPP CFC数量是对照组的 1.5倍 ,结论 :重组的hDll 1ext对原始的造血祖细胞具有扩增作用

34. Thus, cells of hematopoietic origin may contribute to the formation of an ectopic skeleton, although they are not sufficient to initiate the process alone.

因此,造血祖细胞可能对异位骨化的形成起作用,尽管仅仅造血祖细胞不能激起这个过程。

35. And it could be used in testing of different hematopoietic factor colony-stimulating activity.

固定制片后适于多种染色并可长期保存。

36. It will provide a new method and idea for the clinical therapy to those cancer patients who suffer the obstruction of hematopoietic function from the radiant therapy.Methods and Result: 1.

在临床上,为各类肿瘤患者在放化疗后引起的造血功能障碍,以及各类血液疾病的治疗,提供一个新的思路和方向。

37. CD24 is mainly expressed in hematopoietic cell,beside the expression in thymus cell and epithelial cells of brain and pancreas.

在小鼠,CD24主要表达在造血细胞,在胸腺细胞、脑及胰腺的上皮细胞也有表达。

38. Stem cell-like subpopulation has been isolated and identified from hematopoietic system malignancies and solid tumors, and defined as cancer stem cells.

在血液系统恶性肿瘤和实体瘤中均分离和鉴定出具有干细胞特征的细胞群,称之为肿瘤干细胞。

39. When the bone marrow was cultured for 4 - 6 weeks, part of the hematopoietic cells in the bone marrow of AML, CML, MDS patients gained the ability of growing independently.

培养4-6周时,部分急性粒细胞白血病(AML),慢性粒细胞白血病(CML)及骨髓增生异常综合征(MDS)患者的造血细胞获得独立生长的能力。

40. The exogenous IL-3 and NeoR gene of pLXSN can be integrated into DNA genome of BMS, and promote the proliferation of hematopoietic cells.

外源性的IL-3基因及pLXSN上的NeoR已整合到骨髓基质细胞基因组DNA中,并促进造血细胞增殖。

41. Hematopoietic stem cells were harvested from the patients' bone marrow, depleted of T cells, and kept frozen until used for ASCT.

大剂量化疗后收集来自骨髓的自体造血干细胞,去除T细胞,冰冻以备用。

42. Hence, when a hematopoietic stem cell gies rise to an erythrocyte or granulocyte, this is normal, expected differentiation.

如,造血干细胞分化为红细胞或者白细胞,属于正常分化。

43. It occurs at bone marrow and constitutes hematopoietic micro-environment.

它在骨髓局部发生,构成特定的造血微环境。

44. On Ethics Analysis for Producting and Using Hematopoietic Stem Cells From Human Body Navel Blood.

对从人体脐血制用造血干细胞的伦理分析。

45. Results were correlated to TL in CD34+ hematopoietic peripheral blood stem cells and progenitor cells obtained from the same individual patients.

将从同一组个体患者中获取的结果与外周血CD34+造血干细胞和祖细胞的端粒长度进行关联。

46. Th e separated and un-separated cells were cultured with human hematopoietic growt h factors(HGFS)in liquid culture system and CFU-GEMM culture system.

将分离前后的细胞加入造血生长因子进行液态扩增培养和多向祖细胞集落(CFU-GEMM)培养。

47. Ligustrazine can increase the expression of adherent molecule of bone marrow cells in immune mediated AA mice,thus promote the growth of hematopoietic cells.

川芎嗪能增强免疫介导再障小鼠骨髓造血细胞和基质细胞粘附分子的表达,有利于造血细胞的增生。

48. We explored flow cytometry (FCM) to detect sixty patients the expression of related adhesion molecules VLA-5/CD49e on hematopoietic stem and progenitor cell (HSPC) before and after treatment.

并分别在治疗前后采集骨髓标本,采用流式细胞术(FCM)检测患者骨髓造血干/祖细胞相关粘附分子VLA-5/CD49e抗原治疗前后的表达水平。

49. It is suggested that reticulocyte examination and examination of marrow cell will be detected to understand hyperplasia of hematopoietic function for marrow. 2.

建议进行网织红细胞检查,骨髓检查,了解骨髓造血功能的增生情况。

50. Cairo MS,Wanger JE.Placental and/or umbilical cord blood:an alternazive source of hematopoietic stem cells for transplantation[J].Blood,1997,90(12):4665.

张秀文.姬松茸对正常小鼠骨髓造血干祖细胞的影响[J].兰州医学院学报,1993,19(3):143-145.

51. B lineage acute lymphoblastic leukemia (ALL) is the most common type of hematopoietic malignancies in children. The current primary treatment of childhood ALL is combined chemotherapy.

急性B细胞性白血病(B系ALL)是儿童血液系统最常见的恶性肿瘤,是严重威胁儿童健康的顽症,目前主要的治疗手段是抗肿瘤药物的联合化疗。

52. LFA-1 of the BMMNC is high expressed after acute irradiation on the early phase of hematopoietic recovery.

急性放射损伤早期骨髓单个核细胞 L FA 1呈高表达 ;

53. As one of the malignant cloning diseases derived from hematopoietic stem cell, acute leukemia is a "fluid" tumor.

急性白血病是源于造血系统干细胞水平的恶性克隆性疾病,是一种“液体”肿瘤,是否和实体瘤一样也存在血管新生现象?

54. The authors summarize their experience in nursing the patients with fungus infections from malignant diseases in hematopoietic system treated with Sporanox.

总结斯皮仁诺治疗造血系统恶性疾病继发真菌感染患者的护理体会。

55. Chronic myelogenous leukemia (CML) is a clonal myeloproliferative disease of transformed hematopoietic progenitor cells.

慢性粒细胞白血病(chronic myelogcnous leukemia,CML)是一种以髓系细胞受累为主的多能造血干细胞的克隆性疾病。

56. Chronic myelogenous leukemia (CML) is a clonal myeloproliferative disorder due to an acquired abnormality in a pluripotential hematopoietic stem cell.

慢性粒细胞白血病(Chronic Myelogenous Leukemia,CML,简称慢粒)是一种起源于多能干细胞异常克隆的恶性增殖性疾病。

57. Preliminary succes has been achieved in application of ex vivo expanded hematopoietic cells in animal model and clinical trials.

扩增后的造血细胞在动物模型和临床上的应用已取得了初步成效。

58. CD44 is a trans-membrane glycoprotein widely expressed on many kinds of cell from epithelial, mesenchymal, hematopoietic and mesodermal tissues.

摘要CD44是属于黏附因子家族的跨膜糖蛋白。它广泛表达于多种内皮细胞、间充质细胞、造血干细胞及中胚层来源的细胞和组织。

59. This study was aimed to investigate the transfection efficiency of adenoviral vector AD5/F35 to hematopoietic malignant cells lines of various origins and AD5/F35 cytotoxicity.

摘要本研究比较AD5/F35腺病毒载体对不同来源的血液系统恶性细胞系感染效率的差异和细胞毒性反应。

60. Objective To address the question of whether the hematopoietic cells involve in the immunopathogenesis of psoriasis.

摘要目的进一步了解银屑病患者骨髓造血细胞是否有异常。

61. Abstract Objective: To study the effect of T-lymphocytes on hematopoietic progenitors in patients with paroxysmal nocturnal hemoglobinuria(PNH).

摘要目的:研究阵发性睡眠性血红蛋白尿症(PNH)患者的T淋巴细胞对造血祖细胞的影响。

62. Myelolipoma is an uncommon adrenal tumor composed of a variable mixture of mature adipose tissue and hematopoietic elements that resemble the content of bone marrow.

摘要肾上腺骨髓脂肪瘤是一种不常见的肿瘤病变,由不同比例的成熟脂肪细胞与类似类骨髓的造血细胞混合而成。

63. Adrenal myelolipoma, whith is composed of hematopoietic and adipose elements, is a rare benign tumor.

摘要肾上腺骨髓脂肪瘤是罕见,良性,含有造血及脂肪成分的肿瘤。

64. Myelodysplastic syndromes are refered to as a group of diseases characterized by abnormal clonal proliferation of hematopoietic stem cells with pancytopenia and dysplasia.

摘要骨髓增生异常综合徵是以造血干细胞的异常克隆性增生、血细胞减少、骨髓出现病态造血为特徵的一类疾病。

65. Bone marrow hematopoietic microenvironment occupies the medullary cavities of bones throughout the skeleton and provides support for hematopoiesis and immune cells development.

摘要骨髓造血微环境存在于全身骨骼的骨髓腔内,是机体造血以及免疫细胞发育的场所。

66. Abstract: Objective To investigate the changes of bone marrow hematopoietic stem / progenitor cells and its mechanism after cyclophosphamide (CY) treatment in mice.

文章摘要: 目的探讨环磷酰胺(CY)对小鼠骨髓造血干/祖细胞损伤的作用特点与机制。

67. Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor.

文章简介:内容代码开始DC,et al.

68. Methods Cord blood was collected seperately from cord vein and artery.CD34+ cells were detected by FACs, CFU-GM semisolid agar culture, and hematopoietic growth factors(HGFs) by ELISA.

方法分别测定脐动脉和脐静脉血中CD34+细胞、粒-区噬系细胞集落(CFU-GM)及造血生长因子含量;

69. Methods under the same condition with hematopoietic factors in the liquid culture, compared the sequential expansion group and once for all expansion group with or without stroma celllayer.

方法在相同细胞因子组合下,用体外液体培养比较脐血有核细胞程序扩增组与一次扩增组及有无基质层条件下的优劣。

70. Methods: Observing the effect of YSSXT on hematopoietic, immunologic, anti-infection and body resistance of model mice of aplastic anemia.

方法:观察了该药对小鼠造血功能、免疫功能、抗感染力和抵抗力的影响。

71. In the present study, the effects of G-CSF gene therapy was investigated on the recovery of murine hematopoietic suppression induced by high dose of cyclophosphomide (Cy) .

本实验观察了成纤维细胞介导的G-CSF基因疗法对大剂量化疗后造血功能损伤小鼠的恢复作用。

72. In this review the origin and identification of osteoclasts and regulation of mobilizing hematopoietic stem cells, as well as osteoclasts and osteoimmunity were mainly concerned.

本文就破骨细胞的发育来源与鉴定、破骨细胞与造血干细胞动员的调节及破骨细胞与骨免疫进行综述。

73. This review describes the origin and precise location of HSC in the embryo and in AGM region, the hematopoietic microenviroment and the hemato- poietic regulatory mechanisms in AGM region.

本文综述了有关造血干细胞在胚胎和AGM区中的起源与定位 ,AGM区造血微环境以及其中的分子调控机制等问题。

74. In this study, M-CSF and EDAG are selected to explore the molecular mechanism of hematopoietic regulation.

本文选择了巨噬细胞集落刺激因子(M-CSF)和新发现的造血相关基因(EDAG)作为研究造血调控分子机制的入门。

75. Hemopoietic pro-genitor cells, hematopoietic stem cells, hematopoietic microenvironment etc. show dose related damage after irradiaton, consequently, hematopoietic function is destroyed.

机体受到照射后,造血祖细胞、造血干细胞以及造血微环境等都会产生与照射剂量相关的损伤而影响造血机能。

76. Platelets formed by the megakaryocytes derived from hematopoietic stem cells of such mice contain FVIII stored in alpha granules along with Von Willebrand factor, the natural carrier for FVIII.

来源于造血干细胞的小鼠巨核细胞形成的血小板含有储存在阿尔法颗粒连同VWF因子的凝血因子VIII,也就自然承运凝血因子VIII。

77. It is of adrenal origin composed of mature adipose tissue and a variable amount of hematopoietic elements (myeloid and erythroid cells).

此病灶从肾上腺长出,含有成熟的脂肪组织和造血细胞。

78. Human CD45, CD19, CD3 markers on cells from NOD/SCID murine peripheral blood(PB), bone marrow(BM), thymus were detected by FCM from 4 to 10 weeks after hematopoietic stem cell transplantation.

每隔2周采血至10周,流式细胞术动态检测人源淋巴细胞CD45、CD19、CD3抗原。

79. The survival rates and hematopoietic reconstitution of mice in each group were observed and compared. Human hematopoiesis was detected by means of PCR and immunohistochemistry.

比较各组小鼠的存活率及造血恢复情况,并应用多聚酶链式反应(PCR)和免疫组化方法观察小鼠体内人源细胞植入情况。

80. Lagasse E, Connors H, Al-Dhalimy M, et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo[J]. Nat Med, 2000, 6:1229.

潘兴华,韩毅冰,郭坤元,等.成体干细胞的分化潜能及在修复重建中的应用前景[J].中国修复重建外科杂志,2002,16:329.

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