interferon

interferon

1. Philip and I did that in August 1993,and then I started treatment that combined interferon,an immune-boosting therapy,and chemo.

1993年8月，我和我丈夫菲利普按照波克博士说的去做了。之后，我开始注射干扰素，这是一种免疫推进疗法，并进行化疗。

2. In 38 CML patients, 34 (89.5%) were positive, with one having a typical t(9;22) at first, which changed into negative after having been treated with interferon for 38 months.

38例CML患者中 ,bcr/abl阳性为 34例 ,占 89.5% ,其中 1例患者发病时 ,细胞遗传学显示典型的t(9;2 2 ) ,应用干扰素治疗 38个月后 ,bcr/abl基因转为阴性 ;

3. CMP can induce human peripheral blood lymphocyte to produce interferon,interleukin,tumor necrosis factor and granulocyte macrophage colony-Stimulating factor.

CMP能诱导人血淋巴细胞产生干扰素、白细胞介素、肿瘤坏死因子与粒-巨噬细胞集落刺激因子。

4. Dr.Farrar added: "Up until now, interferon has always been appreciated for its role in inhibiting virus infections.

Farrar补充说：”直到现在人们仍然主要关注干扰素在抑制病毒感染中的作用。

5. Effect of interferon on HBV determined by dot hybridization and PCR.

HBeAg、HBV DNA斑点杂交以及定量PCR检测在评价干扰素抗HBV疗效的价值探讨

6. Prof.Janssen: Interferon can definitely not be used there because that gives too many side effects.

Janssen教授：对于失代偿肝硬化的患者，干扰素肯定是不能用，因为副作用太多。

7. Pro.McCaughan: I'm a bit of a nealist about the two forms of pegylated interferon.

McCaughan教授：对这两种干扰素的看法，我比较倾向于现实主义。

8. An important side effect of interferon is worsening of liver disease with treatment, which can be severe and even fatal.

一个重要的副作用是肝病治疗方案恶化，这个可能非常严重和致命。

9. Several specifically targeted antiviral therapies notably protease and polymerase inhibitors are promising but must be used in combination with pegylated interferon and ribavirin.

一些有特殊靶向的一些蛋白酶和聚合酶抑制剂有利于抗病毒，但仅适用于干扰素和利巴韦林的联合治疗中。

10. If they are favorable, interferon may be on the way to becoming one of the best wonder drugs yet-a natural one.

一旦成功，干扰素就将成为最佳的天然的灵丹妙药。

11. The combination regimen can also adopted in patients failed in treatment with interferon monotherapy.

两药复合方案还可用于治疗干扰素单独治疗失败的患者。

12. Clinical why to go up to treat chronic second liver with interferon?

临床上为什么用干扰素治疗慢性乙肝?

13. The main products are: peptide complex liver (hepatocyte production factor), calf blood extract, brain protein, a pioneer on the 4th, cefadroxil and interferon and other products.

主要产品有： 肝复肽(促肝细胞生产因子)、小牛血去蛋白提取物、脑蛋白、先锋四号、羟氨苄和干扰素等产品。

14. They raise the antiviral responses in the infected cells by inducing several interferon inducible pathways.

主要通过几种干扰素诱导途径来提高感染的细胞抗病毒应答。

15. Human interferon Regulatory Factor，IRF Elisa Kit...

人干扰素调节因子（IRF）试剂盒；

16. Their outside individual nucleus cell is in week blood the leucocyte interferon that small amount produces only after virus is atttacked.

他们的外周血单个核细胞在病毒攻击后仅产生低量的白细胞干扰素。

17. He experienced a persistent fever until interferon was discontinued.

他持续发热，直至干扰素停用。

18. Previously, we use lamivudine, adefovir and interferon, but nowadays we use some new drugs, so how can we use it?They are introduced to new guidelines.

以前我们用拉米夫定、阿德福韦和干扰素治疗乙肝，但是现在我们又有一些新药。

19. It seems to be the interferon that helps the liver.But getting rid of HCV also helps, which seems to be why patients who got the pegylated interferon-ribavirin combination did the best.

似乎是干扰素帮助患者肝脏的恢复，但是，去除了C型肝炎病毒后，干扰素仍然能帮助患者的恢复，这似乎是为什麽接受长期干扰素-病毒唑联合治疗的患者治疗的效果最好。

20. But the interferon was something else .The treatments made him so nauseated all he could do was lie on his couch.

但干扰素则大为不同，干扰素的治疗让他恶心不止，他只能躺在沙发上。

21. But in many Asian countries and several European countries, peglated interferon is a popular first course therapy.

但是在亚洲和一些欧洲的国家，聚乙二醇干扰素作为一线治疗很常见。

22. But if RNAi had an ancestral role in virus restriction it seems to have been subsumed in vertebrates by the interferon pathway.

但是如果RNA干扰在病毒限制中存在保守作用，那么它应早已通过干扰素通路的方式被归入脊椎动物。

23. But no one's really paid attention to interferon and its role in regulating memory.

但是对干扰素和其在记忆调节中的作用却很少关注。

24. Xie: The combination of pegylated interferon and ribavirin is the best approach in HCV antiviral therapy, but this gold standard therapy is not for every patient.

但这种治疗的金标准不是适用于每一个患者。

25. As a etiologic agent, the persistence of HCV in extrahepatic tissues may take an important role in the relapse as well as the chronicity of hepatitis C after discontinuation of interferon therapy.

作为致病因子的HCV持续存在肝外多种脏器细胞内，在丙型肝炎慢性化和干扰素治疗后病情复发中可能起重要作用。

26. You mean combination therapy or monotherapy? Nucleotide analogue with interferon combination?

你说的是联合治疗或者单药治疗吗？核苷类似物联合还是和干扰素联合？

27. Q: The hepatitis B patients which treat with interferon now appear rebound, you recommend the application to other type of interferon, or switch to nucleoside drugs?

使用干扰素进行治疗乙型肝炎患者现在发现有反弹，你建议对于该情况，是改用别的干扰素还是改用核苷类药物？

28. Its biological and antigenic characteristics are as same as that of the interferon induced in vitro from the serum of grass carp.

其特性与病毒体内诱导草鱼产生的干扰素相一致且具有相同的抗原性,表明两者是同一种干扰素.

29. It is active in preventing cancer, inducing interferon, adjusting cellular immunity, reducing glutamicpyruvic transaminase, recovering hepatocyte function and preventing the cirrhosis of liver.

具有抗肝中毒，降低谷丙转氨酶，恢复肝细胞功能，防止脂肪性变等作用，防止肝硬化。

30. I tried a lot many years ago, try to seroconvert from e antigen with e antigen positive, so in that case you should be able to use interferon.

几年以前我就做了很多尝试，使HBeAg（+）的患者发生血清转换，在这种情况下，应该使用干扰素。

31. To 1980, the person such as Ye of American scientist rich uses gene to recombine a technology, recombine the gene that controls interferon production into coliform organisms, the made producer that becomes interferon.

到1980年，美国科学家博耶等人采用基因重组技术，把控制干扰素生产的基因重组进大肠杆菌，使之成为干扰素的生产者。

32. Doctors facing the same phenomenon in SARS patients tried to quell the storm by administering interferon and cytokine-suppressing corticosteroids.

前几年发生的SARS也有相同的现象，医师会给予SARS病患干扰素和可抑制细胞素的皮质类固醇，以平息细胞素风暴。

33. How does the pharmaceutical grade Interferon make?

医疗用的干扰素是如何制成的?

34. What are the connection of pumpkin seed, plantago seed,safflower flower, Japanese honeysuckle and Interferon?

南瓜子、车前草、金银花、红花与免疫力之关连?

35. The double-stranded- RNA-dependent protein kinase( PKR) is an important component in an antiviral defence pathway that is mediated by interferon( IFN) in vertebrates.

双链RNA依赖的蛋白激酶(KR)脊椎动物中由干扰素介导的抗病毒防御机制的重要组成部分。

36. TLR2, which is activated by bacteria, stimulates the release of a blend of cytokines that does not include interferon but is more suited to activating an effective antibacterial response by the body.

受细菌活化的TLR2，则会刺激不同组合的细胞素释出，其中虽不包括干扰素，但是却更能激发身体内对抗细菌的反应。

37. Possibly the point is that you have a maximum response of endogenous interferon but the virus itself blocks the effects of interferon.

可能关键就是虽然你有最大内生干扰素应答，但病毒本身阻止了干扰素的效果。

38. Trials of Phyllanthus herb plus interferon versus interferon alone were also included.

叶下珠合用干扰素与单用干扰素比较的随机试验也予以纳入。

39. Never use telbivudine with interferon as this is not safe.

因此，不能应用这种联合，这样不是很安全。

40. Therefore, when you give ribavirin to the patients in addition to the interferon, it makes it easier because the viral replication is already inhibited.

因此，如果除了干扰素以外还加用利巴韦林，治疗会更有效，因为病毒复制已经被抑制了。

41. Therefore, we propose this would suggest a possible autoimmune mechanism for the development of pyoderma gangrenosum and exacerbation of psoriasis with pegylated interferon therapy.

因此，我们提出聚乙二醇化干扰素治疗后出现坏疽性脓皮病和银屑病加重的可能自身免疫性机制。

42. Therefore, we tend to be a little more aggressive and if a patient has borderline depression we would treat them before we would treat with interferon.

因此，我们治疗可能有些激进，如果患者在抑郁症的临界点上，我们会在给予干扰素之前就治疗抑郁症。

43. The International Society for Interferon and Cytokine Research.

国际干扰素和细胞因子研究会。

44. International Digest： For hepatitis C patients being treated with pegylated interferon and ribavirin， how can we improve the SVR? Do you have any suggestions or advice for us?

国际肝病：对于正在接受聚乙二醇干扰素和利巴韦林治疗的丙肝患者，您能给我们一些提高持续病毒学应答的建议吗？

45. Hepatology Digest: It is the combination of interferon and ribavirin that will continue to play an important role.

国际肝病：那么干扰素和利巴韦林的联合应用依旧还会是重要的治疗方法吗？

46. In hepatitis C patients, occult HBV coinfection will reduce the response to interferon.

在丙肝感染者中，重叠感染隐匿性HBV会影响干扰素的疗效。

47. Lamivudine and interferon combination with or without lamivudine priming showed encouraging results in clinical trial.

在临床应用中，拉米夫啶和干扰素（与拉米夫啶联用或不与拉米夫啶联用）都显示了令人振奋的效果。

48. HBeAg seroconversion at the end of1 year was29% for combination,18% for lamivudine,19% for interferon and4% in placebo.

在临床应用中，拉米夫啶和干扰素（拉米夫啶联用或不与拉米夫啶联用）显示了令人振奋的效果。

49. In the meantime, individualizing dose and duration of pegylated interferon and ribavirin might improve sustained virologic response rates in patients with hepatitis C.

在此期间，干扰素和利巴韦林的个性化剂量和疗程可能改进了丙肝患者的耐药性。

50. In the interim prior to licensure of these new small molecule inhibitors, established therapy with pegylated interferon and ribavirin can be tailored.

在这些新型小分子抑制剂获得临床使用许可前，我们可以对业已形成的聚乙二醇化干扰素联合病毒唑的治疗方案进行适当的修改。

51. Using purified interferon, a research team under the direction of biochemist Christian B.Anfinsen is mapping interferon's molecular structure at the National Institutes of Health in Bethesda, Md.

在马里兰州贝塞斯达国立卫生研究生的生物化学家克.芬森指导下的一个研究小组正在使用提纯的干扰素,对干扰素的分子结构进行研究.

52. Using purified interferon , a research team under the direction of biochemist Christian B.Anfinsen is mapping interferon's molecular structure at the National Institutes of Health in Bethesda, Md.

在马里兰州贝塞斯达国立卫生研究生的生物化学家克.芬森指导下的一个研究小组正在使用提纯的干扰素，对干扰素的分子结构进行研究。

53. Analysis of therapeutic effect of interferon in combination with podophyllin on condyloma acuminatum patients.

复方足叶草脂;干扰素;尖锐湿疣,,复方足叶草脂;干扰素;尖锐湿疣,1资料和方法,2结果,3讨论,参考文献:

54. A patient who is old, as you say, that is in good physical condition could very well receive treatment with interferon and ribavirin.

如你所说，老年患者，如果身体状态良好，就能接受干扰素联合利巴韦林治疗。

55. Some side effects may be reduced by giving interferon at night or lowering the dosage of the drug.

如果在晚上服用干扰素或减少用量，可以降低一些副作用。

56. Pregnant women should not be treated with interferon.

孕妇不应使用干扰素治疗。

57. Antivirus therapy is effective for cervical erosion, the effect of Recombination Interferon Cork a2b is superior to Policresulen for cervical erosion.

宫颈糜烂经抗病毒治疗有效，本研究结果应用干扰素治疗宫颈

58. For those one, I don't think interferon has indications, so in that case, our choices are nucleotide/nucleoside analogues.

对于这些患者来说，并没有使用干扰素的指征，因此，我们的选择是核苷类似物。

59. In these so-called difficult-to-treat cases you have to either increase the dose of pegylated interferon or the dose of ribavirin or in the future perhaps we can add protease inhibitors.

对于这些所谓难治性的病例，你必须增加聚乙二醇干扰素或者利巴韦林的剂量，或许在未来可能加用蛋白酶抑制剂进行治疗。

60. We must have a good antiviral response to interferon and ribavirin, which significantly lowers the risk of resistance to the antiviral drug used in the combination.

对干扰素和利巴韦林治疗的反应性一定要好好，这样可以显著地降低联合用药时的耐药风险。

61. Meanwhile, the effect of Arctigenin Compound on inducing the production of interferon in normal mice was observed.

对正常小鼠研究诱生干扰素水平。

62. In the old patient, it is important to consider his/her general condition when considering interferon and ribavirin treatment .

对老年患者而言，在开始干扰素联合利巴韦林治疗前选择合适的治疗条件显得尤为重要。

63. Interferon, inducers have only been used to a limited extent in man.

干扰素、诱生剂只是在有限程度上对人用过。

64. Interferon generation method is by Finland the scientist blocks Li Kante the doctor invents, he extracts leucocyte to produce interferon from inside blood.

干扰素产生方法是由芬兰科学家卡里·坎特儿博士发明的，他从血液中提取白细胞便产生干扰素。

65. Interferon is a kind of antiviral protein substances,which can treat RV enterities.

干扰素作为一种广谱的抗病毒蛋白质,能对RV引起的肠炎起治疗作用。

66. Professor Keeffe: I think interferon alone is a reasonable option to treat patients.And particularly if the ALT level is higher and the HBV DNA is lower.Those patients are good candidates.

干扰素可以作为一线乙型病毒型肝炎抗病毒治疗药物，尤其是对于谷丙转氨酶较高而病毒载量较低的患者来说，但是单独应用即可。

67. Interferon can be used to cure cancer.

干扰素可以用于癌症治疗。

68. Interferon is probably the most significant nonspecific antiviral substance.

干扰素可能是最重要的一类非特异性抗病毒物质。

69. Interferon is almost always host species-specific in function. By contrast, interferon activity is not specific for a given virus; the replication of a wide variety of virus can be inhibited.

干扰素在功能上通常是宿主种特异性。相反，干扰素活性对各种病毒均有效；能广泛抑制各种病毒的复制。

70. The study of mammalian interferon already completed, the study of bird interferon also get on quickly, especially in chicken and duck.

干扰素在哺乳动物中已进行了深入的研究,禽类干扰素的研究也已经取得了很大的进展。

71. How does the Interferon help to mount an attack against cancer cells?

干扰素如何抑制癌细胞生长?

72. Interferon may be effective in treating some herpes virus infections of the eye.

干扰素对治疗某些眼部疱疹病毒感染可能有效。

73. Interferon is not the cell gets of virus invade after catching, virus take-overs inside the cell " chemical plant " .

干扰素并不是细胞受到病毒的侵染之后，病毒就接管细胞内的“化工厂”。

74. Interferon strengthens the body's response against disease by making the immune system more effective.

干扰素应通过增强免疫系统的效用来提高机体的抗病能力。

75. Interferon could significantly prolong the chr onic period and survival period of CGL patients.

干扰素有助于延长CGL患者慢性期及生存期，延缓急变的发生。

76. Interferon has a lot of potential toxicities, and patients need to be seen more frequently.

干扰素有很多的毒副反应，需要观察的更为频繁。

77. What are the side effects of interferon therapy?

干扰素治疗的副作用是什么?

78. Interferon is scarce and this has been a major obstacle in studying its effects.

干扰素的量是很少的，这是研究干扰素作用的主要困难所在。

79. What kind of disease can use the Interferon therapy now?

干扰素目前运用于治疗何种疾病?

80. Interferon（IFN） is a kind of protein excreted by human somatic cells.It has broad-spectrum antivirus, anti-tumour function and immunoregulation activity.

干扰素（IFN）是一类人体细胞分泌的蛋白质，具有广谱的抗病毒、抗肿瘤和免疫调节活性。