murine

murine

1. The second nucleotide in optimal human CpG motifs was thymidine, while in less active human CpG motifs or optimal murine CpG motifs, it was purines.

5′ GTCGTT 3′和 5′ GTCGTC 3′ 2个基序对人B细胞有高度免疫刺激活性 ,第二位碱基均为“T” ,而在小鼠CpG基序中该位碱基为“G”或“A”。

2. abelson murine leukemia virus(A-MuLV)

abelson小鼠白血病病毒

3. Antitumor Activity of Mitoxantrone-nanosphere again Murine Liver Tumor H22.

Asian Journal of drug metabolism and pharmacokinetics 核心期刊 2004;

4. The establishment of two murine hepatocarcinoma substrains provides a useful animal model for the study of mechanism of the lymphatic metastasis.

HepA肝癌不同淋巴转移能力亚系的建立，为研究肿瘤经淋巴管转移机理提供了良好的肿瘤淋巴转移动物模型。

5. Feeder cells with murine embryonic fibroblasts(MEF) were better than that with human embryonic fibroblasts(hEF), or STO or bovine embryonic fibroblasts (bEF).

MEF、STO、bEF和hEF可提高人原始生殖细胞(PGCs)的贴壁率,能促进PGCs源的人类胚胎干细胞(ES)的分离效率; 以MEF作为饲养层效果较好。

6. MES23.5 cell line, which served as a useful tool for studying neurodegenerative disease, is a dopaminergic neuroblastoma derived from somatic cell fusion of rat embryonic mesencephalon cells and the murine neuroblastoma-glioma cells.

MES 2 3 5细胞作为研究神经变性疾病的工具 ,是一种杂交瘤性多巴胺能神经元细胞系 ,由大鼠胚胎中脑细胞与小鼠神经母细胞瘤 胶质瘤细胞系N18TG2杂交而成 .

7. Moloney murine leukemia virus reverse transcriptase

MMuLV-RT

8. The inhibitor of NOS (aminoguanidine) only partially inhibited the C. albicans-induced apoptosis in murine in vivo.

NOS抑制剂氨基胍仅能部分抑制白念菌诱导的小鼠胸腺细胞凋亡；热灭活的白念菌不能诱导胸腺细胞凋亡。

9. TXT can inhibit the proliferation of murine angiosarcoma cell line ISOS-1 strongly,it can not only act on G2-M phase,but also induce apoptosis.

TXT能强烈抑制鼠血管肉瘤细胞株ISOS-1的增殖,这种抑制作用可能通过作用G2-M期及诱导细胞凋亡来实现的。

10. WSW also selectively replicated in murine and human lung cancer cell lines but not in normal cells.

WSW具有选择性在肿瘤细胞复制的能力，而不论在人类或小鼠正常细胞中皆无毒杀作用。

11. Our data demonstratse that YCP can promote the formation of a granular layerin the scale epidermis of murine tail,thus correcting the pathologic process of parkeratsosis in the psoriatic epidermis.

YCP能促进颗粒层表皮细胞形成，使银屑病角化不全病变得到纠正。能提高机体免疫力，具有活血化瘀，改善微循环，抗炎止痒作用。

12. Wang QB,Lei LS,Sun LS,et al.Effects of Ganoderma polysaccharide on IL-2 and IL-3 mRNA expressions in murine splenocytes in vitro[J].Chin Pharmacol Bull,1998,14(4):342-4.

[1]王庆彪,雷林生,孙莉莎,等.灵芝多糖体外对小鼠脾细胞IL-2,IL-3mRNA表达的影响[J].中国药理学通报,1998,14(4):342-4.

13. A murine rodent.

一个鼠科啮齿动物

14. Some compounds exhibit cytotoxicity toward KB cells and P388 murine leukemia cells,and inhibitory activity against P-glycoprotein over expressing of adriamycin resistant cell line,K562/Adr cells.

一些成分在抑制KB细胞、P388白血病细胞和P-糖蛋白方面显示了较好的活性。

15. Eleven human-specific amino acid changes were identified in the PACAP precursors which are conserved from murine to African apes.

中性检验和分子系统学分析显示，人群中小脑症基因丰富的多态性可能是新石器时期以来人群的迅速增长和达尔文正向选择两种力量共同作用的结果。

16. He found that irradiation of micrococcus and of murine lymphoma cells under anoxia gave fewer singlestrand breaks.

他发现，在缺氧时照射小球菌和小鼠琳巴瘤细胞产生的单链断裂较少。

17. Hematoporphyrin derivative (HPD) was conjugated with a murine monoclonal antibody (3H11) against human gastric cancer through bovine serum albumin (BSA) as an intermediate.

以牛血清白蛋白为中间载体,将血卟啉衍生物(HPD)与抗胃癌单克隆抗体3H11交联。

18. For the future works, there is one paper reported about a murine mode of genetic susceptibility to lead bioaccumulation.

但我们采用协方差分析尽量对性别、年龄、工龄、吸烟和饮酒这些混杂因素加以控制，使结果可信。

19. And used MTT assay, ELBA, FACS to value the effects of BMSC on the murine immunocompetent cells.

体外实验采用MTT法、ELISA和FACS等方法检测BMSC的免疫调节作用。

20. In a preious study researchers found the zinc finger antiiral protein (ZAP) capable of inhibiting Moloney murine leukemia irus and Sindbis irus replication.

先前研究发现锌指结构抗病毒蛋白能够抑制莫洛尼(氏)鼠白血病病毒和辛德比斯病毒的复制。

21. Mukherjee T,Copperman AB,McCaffery C,et al.hydrosalpinx fluid has embryotoxic effects on murine embryogenesis:a case for prophylactic salpingectomy.Fertile Steril,1996,66(5):851-853.

刘冬娥李艳萍吕祁峰马燕琳周庆娥邓利.辅助生殖技术治疗周期中宫腔积液25例分析.中国实用妇科与产科杂志,:.

22. New insights into these mechanisms are now arising from femur, calcaneus, humerus model of cancer pain in murine and tibia model in rats.

初步研究表明,癌症痛有其独特的神经化学机制,骨质破坏、外周敏化、中枢敏化及神经侵蚀都参与了癌症痛的产生。

23. Panteleyev A A,Paus R,Wanner R,et al. keratin 17 gene expression during the murine hair cycle[ J]. J Invest 缺项?

卓明英,杨军.鼻息肉上皮细胞角蛋白的表达及临床意义[J].临床与实验病理学杂志.1995,11(3):213-214.

24. In addition, only certain murine mAb isotypes hae been shown to effectiely bind to and actiate elements of the human immune system, thereby triggering cytotoxic effector functions10.

另外，只有某些亚型的鼠单抗可以有效的结合并激活人免疫系统，以激发细胞毒作用[10]。

25. Subsequent advances in technology have allowed for humanized Mabs, which have different pharmacokinetic properties than murine Mabs in humans.

后来技术的发展使人源化单克隆抗体成为可能，它和鼠源单克隆抗体的药代动力学属性不同。

26. Safford KM,Safford SD,Gimble JM,et al.Characterization of neuronal/glial differention of murine adipose-derived adult stromal cells[J].Exp Neurol,2004,187:319.

吴孟海,刘斌.神经节苷脂对脂肪间充质干细胞向神经元样细胞分化的影响[J].中国煤炭工业医学杂志,2005,8:1259.

27. When compared with the viral control group that was not received AM therapy the expression of TNF-amRNA in murine myocardium of CVB VMC decreased(P<0.05) when treated with AM.

和未用药的病毒对照组比较，应用黄茂治疗后，CVB3心肌炎小鼠心肌中TNF一a mRNA表达下降(P<0 .05)。

28. Amphotropic murine type C oncovirus

嗜两栖鼠C型肿瘤病毒

29. Ecotropic murine type C oncovirus

嗜环境小鼠C型肿瘤病毒

30. Keywords CD69;eosinophils;asthma;murine model;

嗜酸性粒细胞;哮喘;小鼠模型;

31. Inhibition of GSK3 in a preclinical murine model of MLL leukaemia provides promising evidence of efficacy and earmarks GSK3 as a candidate cancer drug target.

在MLL白血病一个临床前鼠模型中，抑制GSK3可提供有效性的令人鼓舞的证据，并标记了GSK3作为候选的癌症药物靶点。

32. In the post-genomic era, many human novel genes can be predicted by bioinformatic analysis. The zebrafish and murine homologous genes can be easily identified too.

在后基因体时代,许多新颖人类基因,可以利用生物资讯工具来预测,斑马鱼及鼠类的同源基因也可以很容易地被预测出来。

33. Inducible nitric oxide synthase inhibitors reduce urinary markers of systemic oxidant stress in murine proliferative lupus nephritis.

在增殖型狼疮性肾炎小鼠中诱生型一氧化氮合酶抑制剂减少尿液中组织氧化应激标记。

34. During the research we have discovered a new variant form of murine IL-18 that has been entitled in genbank(AY 362457).

在构建过程中，我们发现了一个新的mIL-18的突变形式，该序列已被收录于Genbank（AY 362457）。

35. Murine typhus is relatively common throughout the world and is transmitted by fleas.

地方性斑疹伤寒由鼠蚤传播，在世界范围都比较普遍。

36. bone marrow mesenchymal stem cells of murine

大鼠骨髓间充质干细胞

37. Its protein product was found to also suppress metastasis of melanoma cells and murine mammary carcinoma cells.

它所编码的蛋白还可以抑制黑素瘤细胞和小鼠乳腺癌细胞的转移。

38. Mckay A,Leung BP,McInnes IB,et al.A novel antiinflammatory role of simvastatin in a murine model of allergic asthma[J].J Immunol,2004,172(5):2 903.

宋立强,戚好文,李研,等.氟伐他汀对哮喘气道重塑的抑制作用及机制研究[J].中国病理生理杂志,2002,18(12):1478.

39. In practice, murine mAbs were mostly limited to acting as targeting agents for radioactie elements or cytotoxins that might kill targeted tumour cells.

实际使用时，鼠单抗通常仅限于作为靶向因子，便于放射性元素或细胞毒物质杀伤肿瘤细胞。

40. Tim Holy and Zhongsheng Guo at Washington University School of Medicine in Missouri discovered the murine melodies by accident.

密苏里州华盛顿医学大学的提姆何利与郭中山当初是意外发现鼠类的旋律。

41. This study focused on the gene expression and protein function of Mess1.It was found that the messenger RNA of Mess1 was widely distributed in murine tissues but differentially expressed in various cell lines.

对 Mess1的基因表达和蛋白功能进行研究 ,发现其 m RNA在鼠组织中广泛分布 ,但在不同细胞系中表达显著不同 ;

42. There was a fusion cell strain obtained from murine Lewis lung cancer AL9901 cells and the BmDC. Molecule expression of the fusional cells and BmDC were detected by S P immunocytochemical staining.

将其与小鼠Lewis肺癌细胞系AL9901融合,并以S-P免疫细胞化学染色法检测融合细胞和BmDC上有关分子的表达。

43. Murine ARS reticulum sarcoma cells, when incubated with 1.5, 2.0 and 2.5% DMSO in vitro, were induced to differentiate into macrophage like cells.

小鼠ARS腹水型网状细胞肉瘤瘤株加1.5、2.0、2.5%DMSO体外培养,被诱导出现了巨噬细胞样分化。

44. Expression and purification of murine MIF in E.col

小鼠MIF在大肠杆菌中的表达及纯化

45. Thylaxoviridee murine carcinomatis virus

小鼠乳腺癌病毒

46. The murine ortholog of GPRA was up-regulated in a mouse model of ovalbumin-induced inflammation.

小鼠同源GPRA在卵白蛋白诱发炎症的小鼠模型中出现上调。

47. murine uterocervical carcinoma number 14( U 14 )

小鼠宫颈癌U14

48. Murine uterocervical carcinoma number 14

小鼠宫颈鳞癌14号

49. Signal peptide of murine plasmingen

小鼠纤溶酶原信号肽

50. murine hepatoma 22 clonal cell strains

小鼠肝癌H22细胞克隆株

51. Murine ascites hepatocarcinoma cell strain

小鼠腹水型肝癌细胞株

52. murine ultra high sulfur keratin gene

小鼠超高硫角蛋白基因

53. Methods:sIL-4R eDNA fragment is synthesized from spleen cells of BALB/c murine stimulated with IL-4 in vitro using RT-PCR, the sequence of recombinant sIL-4R is indentified by sequence analysis .

应用分子克隆技术构建sIL-4R基因腺病毒载体，并经脂质体介导与腺病毒骨架载体PJM17共转染293细胞，获得重组腺病毒。

54. Murine ACD induced by DNFB for three times were elicited.

建立DNFB三次诱发的小鼠左耳ACD的动物模型。

55. Xenotropic murine type C viruses

异嗜性鼠C型病毒

56. Xenotropic murine type C oncovirus

异嗜性鼠C型肿瘤病毒

57. Mathew RC &Boros DL. Regulation granulomarous inflarnmation in murine schistosoniaiss [J].J Immunol, 1986,163:1093.

张悟澄,陈金华,曾庆仁,等.对日本血吸虫虫卵肉芽肿形成的人工诱发特异性免疫调节[J].寄生虫学与寄生虫病杂志,1983,1(3)：154.

58. Yasuhisa Matsui, Deniz Toksoz, Satomi Nishikawa, et al.Effect of steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture.Nature 1991;353:750.

徐令,黄绍良,李树浓,等.人胚胎成纤维细胞对人胚胎干细胞生长的作用.叶鑫生:干细胞和发育生物学.北京:军事医学科学出版社,2000,121.

59. Rezkalla S, Kloner RA, Khatib G, et al. Beneficial effects of captopril in acute coxsackie virus murine myocarditis[J].Circulation,1990,81(3):1039.

成建定，陈玉川，胡丙杰.病毒性心肌炎纤维连接蛋白的免疫组化初步研究[J].法医学杂志，1999，15（1）：9.

60. The effect of 12C6+ beam irradiation on AdCMV-GFP(a replication deficient recombinant adenoviral vector containing CMV promoter and green fluorescent protein) gene transfection efficiency for murine melanoma cell B16 has been investigated.

探讨12C6+离子束辐射对用带有绿色荧光蛋白基因的缺陷性腺病毒(AdCMV-GFP)转染小鼠黑色素瘤细胞(B16细胞系)的影响。

61. Stem cell from murine adipose tissue

提取大白鼠脂肪干细胞的初步研究

62. Objective To explore the effect on immunological roles of peritoneal macrophages caused by murine hepatoma cells with different metastatic ability.

摘要 目的 研究转移程度不同的小鼠肝癌细胞株对腹腔巨噬细胞功能的影响。

63. Murine double minute 2 (MDM2), an oncogene discovered in recent years, can enhance cell sur-vival activity, prolong cell survival duration, promote cell proliferation and stimulate tumor growth.

摘要MDM2为小鼠双微体基因，是近几年发现的一种癌基因，对细胞生长有调节作用。

64. Objective To explore the influence of whole peptidoglycan (WPG) of Bifidobacteria on the gap junctional intercellular communication(GJIC) of murine peritoneal macrophages.

摘要目的探讨双歧杆菌的完整肽聚糖(WPG)对巨噬细胞缝隙连接介导的细胞间通讯(GJIC)的影响。

65. Background: The homogenicity of acute colitis models induced by drinking dextran sulfate sodium (DSS) freely in murine is poor and with high mortality rate.

摘要背景：自由饮用葡聚糖硫酸钠(DSS)诱导的鼠类急性结肠炎模型均一性欠佳，动物死亡率较高。

66. Abstract: Objective To understand anti-tumor effect and mechanism of allicin on murine bladder.

文章摘要: 目的了解大蒜素对小鼠膀胱肿瘤的抗肿瘤效果与机制。

67. Abstract: Objective To observe the effects of Astragalus Membranaceus injection （AMI） on coxsackievirus 133 （CVB3） murine viral myocarditis.

文章摘要: 目的：探讨黄芪注射液（AMI）对柯萨奇病毒133（CVB3）感染小鼠的保护作用。

68. Methods Murine IL 12 cDNA was inserted into optimized HBcAg DNA vaccine pST HBc. The resultant recombinant expression plasmid pST HBc/IL12 was transfected into COS7 cells and its expressed product was detected by ELISA.

方法 将小鼠IL 12基因插入结构优化的DNA疫苗pST HBc,构成pST HBc/IL12 ,将pST HBc/IL12转染COS7细胞 ,ELISA检测培养上清中的HBcAg和小鼠IL 12。

69. Murine schistosomal hepatic fibrosis model was established by infecting mice with Schistosoma japonicum cercariae.Routine transmission electron microscopy was used to observe the liver tissue.

方法 日本血吸虫尾蚴经皮肤感染小鼠建立血吸虫病肝纤维化模型。

70. Methods Male C57BL/6 (6-8wk of age) murine model of Asthma and control group were estabolished with routine method.

方法15只雄性C57BL/6小鼠。

71. Methods: The recombinant aden-ovirus vector carrying murine FLT3 ligand (AdmFL) was constructed, AdmFL and/or ADM were injected into the tumor-bearing mice.

方法:构建携带鼠FL的重组腺病毒载体(AdmFL),单独用其或ADM以及两者联用对实验性肝癌小鼠进行治疗,观察抗肿瘤效果。

72. Methods Using reverse transcription-polymerase chain reaction(RT-PCR),the PIM3 mRNA expression in normal murine ocular tissues was defected.

方法应用逆转录-聚合酶链反应及免疫组化检测PIM3在小鼠眼部组织中的表达。

73. Methods: Our experiment established murine model of VMC by infected BALB/c mice with Coxsackie Virus B3, then the effect of TPN on the death rate and pathologic change of VMC mice were studied.

方法：在给BALB/c小鼠腹腔注射柯萨奇病毒B3成功建立VMC动物模型的基础上探讨了三七总苷对VMC小鼠心肌炎细胞浸润、心肌坏死和死亡率的影响。

74. Methods: Different concentration levels of LMOP suspension were used to B16F1 murine melanoma cells in vitro, and comparing with 8-MOP liquors on the same concentration levels.

方法：将8-甲氧补骨脂素脂质体(LMOP)悬液作用于体外培养的小鼠B16F1黑素瘤细胞，并与等浓度的8-甲氧补骨脂素(8-MOP)溶液作比较，用四甲基偶氮唑蓝(MTT)比色法测定细胞增殖情况；

75. Methods: The influences on the phagocytosis of Murine peritoneal Macrophages, PFC, lymphocyte proliferation,and ADCC of Yupingfeng San were observed.

方法：本文实验观察了不同剂量玉屏风散对小白鼠的腹腔巨噬细胞吞噬功能、PFC、淋巴细胞增殖及ADCC的影响。

76. Examination of the link between leptin and hypothalamic-pituitary-gonadal function has been undertaken mainly in the murine model.

有关瘦素与下丘脑-垂体-卵巢轴功能间的联系的检验已主要在鼠科模型上进行。

77. A complete murine anti cTnI Fab fragment was obtained in this study,which may provide basis for the production of the chimeric anti cTnI antibody.

本实验室获得了完整的鼠源性抗人cTnI单克隆抗体Fab段基因,为鼠抗人cTnI单克隆抗体的人源化改造奠定了基础。

78. In the present study, the effects of G-CSF gene therapy was investigated on the recovery of murine hematopoietic suppression induced by high dose of cyclophosphomide (Cy) .

本实验观察了成纤维细胞介导的G-CSF基因疗法对大剂量化疗后造血功能损伤小鼠的恢复作用。

79. At the present study, these effects are investigated on three aspects in a murine model of sepsis induced by cecal ligation and puncture (CLP) .

本实验采用小鼠盲肠结扎穿孔(cecal ligation and puncture，CLP)致腹腔感染脓毒症模型，从三个方面探讨两种药物对脓毒症机体的作用。

80. The fluidity of membrane lipid regions of normal and leukemic lymphocytes ofhuman and murine origin has been determined by the fluorescence polarizationtechnique using 1,6-diphenyl-1,3,5-hexatriene(DPH) as fluorescence probe.

本工作使用1,6-dipbenyl 1,3,5-hexatriene(DPH)作为萤光探剂,应用萤光偏振技术研究了人和小鼠的淋巴细胞。