oncogenesis

oncogenesis

1. ADRB2 inhibition confers cell invasion and transforms benign prostate epithelial cells, whereas ADRB2 overexpression counteracts EZH2-mediated oncogenesis.

ADRB2受到抑制后促进肿瘤细胞的侵袭和良性的前列腺上皮细胞的转化,因此ADRB2过表达干扰了EZH2调节的肿瘤生成。

2. The Role of bcl-2 Gene Regulating Function and Apoptosis in Oncogenesis of Neuroblastoma

bcl-2基因调控作用与细胞凋亡在神经母细胞瘤发生发展中的作用

3. The overexpression of ILK and MMP-9 genes may play an important role in the oncogenesis and development of NSCLC respectively.

ILK和MMP-9蛋白过度表达可能分别在NSCLC的发生和发展过程中起重要作用。

4. The gene products of p53, C-erbB-2, p21WAF1, CDK4 play a key role in the oncogenesis and development of breast cancer. Their expression could be useful indexes to assess the malignant level and clinical prognosis of breast carcinoma.

p53、C-erbB-2、p21WAF1和CDK4与乳腺癌的发生发展密切相关,可作为判断肿瘤浸润转移、指导治疗和估计预后的参考指标。

5. Though the positive rate of P53 was comparatively lower than that of P21, mutation of P53 gene seems to be a cooperative fac-tor in the oncogenesis of HCC.

P53的阳性率较P21低,但p53的突变似乎也是肝癌发生的协同因素之一。

6. Regulatory Action of Chinese herbs on the Signal Transmission Abnormality in Oncogenesis

中药对肿瘤发生过程中信号转导异常的调整作用

7. Keywords ginsenoside (GS);total saponin of panax ginseng (TSPG);Marek's disease (MD);oncogenesis;mechanism of action;

人参皂苷;人参总皂苷;马立克氏病;肿瘤形成;作用机制;

8. Functional analysis revealed that these proteins were associated with cancer cellular oncogenesis, proliferation,differentiation and metastasis.

从功能上分析这些差异蛋白质与癌细胞的发生、增殖、分化、转移等相关。

9. Signal Transduction with Cellular Oncogenesis

信号转导与细胞癌变

10. Relationship between hypermethylation of Syk gene in promoter and oncogenesis, metastasis of gastric carcinoma

候选抑癌基因Syk启动子甲基化与胃癌转移相关

11. Substantial evidence shows that inflammation promotes oncogenesis and, occasionally, participates in cancer rejection.

充实的证据表明炎症能够促进肿瘤发生,偶尔也会参与癌症排斥。

12. immunohistochemistry oncogenesis or development

免疫组织化学

13. chemical oncogenesis

化学癌形成

14. Most somatic mutations are likely to be 'passengers' that do not contribute to oncogenesis.

大多数的体细胞突变仅仅像是过客而不引起肿瘤发生。

15. A case-control study on the relationship among indoor air pollution, depression and oncogenesis of lung cancer

室内环境污染、神经精神等因素与肺癌关系的研究

16. Keywords cervical carcinoma;VEGF-C;immunohistochemistry;oncogenesis or development;metastasis;

宫颈癌;VEGF-C;免疫组织化学;肿瘤发生发展;转移;

17. Data from this study indicate that the inhibition of p15INK4B and p21WAF1/cip1 may be one of the mechanisms by which HDAC3 participates in cell cycle regulation and oncogenesis.

干涉质粒能诱导p15INK4B基因表达活性的升高,而对p21WAF1/cip1的表达没有什么影响。本研究表明去乙酰化酶3可能是通过抑制p15INK4B和p21WAF1/cip1这种方式来参与周期调控和癌症发生的。

18. Relationship of microsatellite alterations and oncogenesis, development in lung cancer

微卫星改变与肺癌发生发展的关系

19. To evaluate the significance of nm23,c-erbB-2 gene in the oncogenesis and development of pancreatic cancer and the relations between the two genes.

探讨c-erbB-2基因及nm23基因在胰腺癌的发生、发展中的作用以及二者的关系。

20. To explore the functioning of bcl-2 gene family in biological behavior such as oncogenesis,invasion and metastasis and hence reveal their clinical value and application as a whole.

探讨凋亡相关因素Bcl-2、bax对于胆囊癌发病、侵袭及转移等生物学行为的作用,并进而揭示其临床意义及临床应用价值。

21. It suggested there was some kind of interaction existing between nm23, EGFR and Bcl-2 in the oncogenesis and development of lung cancer.

提示表皮生长因子受体EGFR、凋亡抑制基因Bcl-2与抑癌基因nm23在肺癌的发生、发展中可能存在着一定的相互作用。

22. Objective To investigate the relationship between the expression of P27 protein and the oncogenesis and development of cervical squamous carcinoma (CSC).

摘要目的探讨P27蛋白表达与宫颈鳞状细胞癌发生、发展的关系。

23. Objective To study the effects of XIAP expression on oncogenesis and clinical significance of this expression in pancreatic carcinoma.

摘要目的通过检测XIAP在胰腺癌中的表达,探讨其对胰腺癌发生、发展的可能作用及临床意义。

24. Abstract: Objective To investigate the role of telomerase activity in the oncogenesis and progression of human lung cancer.

文摘:目的探讨端粒酶活性表达与肺癌发生发展的关系。

25. This article is about to discuss the expression of homeobox genes in glioma and the possible role of homebox genes i n oncogenesis,suggesting that homeobox genes may be useful in clinical diagnosis.

本文结合有关文献,探讨同源盒基因在胶质瘤中的表达及作用和临床诊断应用前景。

26. viral oncogenesis

病毒致癌作用

27. We have found that HCV infection induces DNA breaks and enhances DNA mutation frequencies, thus explaining the mechanism of oncogenesis of this RNA virus.

目前已发现这个病毒会改变细胞基因修补的功能,因而引起染色体的断裂及细胞基因的变化。

28. Now, zebrafish is extensively used as a vertebrate model system in developmental biology, genetics, oncogenesis, pharmacology, toxicology and environmental science,with increasing scientific outcomes.

目前,斑马鱼被广泛地用于发育生物学、遗传学、肿瘤学、药物学、毒理与环保等方面的研究,不断涌现新的研究成果。

29. Objectives To investigate the expression of P16, P21 and P53 in GCT, to study the relationship among these three factors and to evaluate the features of cytology and oncogenesis and biological behavior of GCT.

目的 检测抑癌基因P16,P21和P53在骨巨细胞瘤(GCT)组织中的表达,探讨它们之间的相关性及与病理分级的关系,以进一步了解GCT的发生,细胞学性质及生物学行为,为临床治疗提供参考。

30. Objective: To investigate the relationship among microsatellite marker alterations on chromosome 3P and 9P and oncogenesis,development in lung cancer.

目的:研究肺癌组织中第3号染色体短臂(3P)和第9号染色体短臂(9P)上微卫星标志物的改变与肺癌发生发展的关系。

31. Objective To study the role of programmed cell death 5 (PDCD5) protein in the oncogenesis and development of renal clear cell carcinoma and its association with the prognosis of the malignancy.

目的探讨PDCD5在肾透明细胞癌发生、发展中的作用及与预后关系。方法采用免疫组织化学方法,对46例肾透明细胞癌组织中PDCD5表达进行研究,对患者存活率进行回顾性随访。

32. Objective To discuss the oncogenesis, clinical manifestation and relative treatment of hand endogenetic cartilaginous tumor.

目的探讨手部内生软骨瘤发生、临床表现、相关治疗问题。

33. Objective To investigate the role of telomerase activity in the oncogenesis and progression of human lung cancer.

目的探讨端粒酶活性表达与肺癌发生发展的关系。

34. Objective To discuss the oncogenesis,devolpement, metastasis of cervical carcinoma through detection of HPA in this tissue.

目的通过对宫颈癌组织中乙酰肝素酶(HPA)的检测,探讨HPA在宫颈癌发生、发展、转移潜力中的作用。

35. Significance of Cell Apoptosis in Oncogenesis on Digestive System Tumor

细胞凋亡在消化系统肿瘤形成中的意义

36. Conclusions Nitric oxide synthase might play an im-portant role in the oncogenesis and development of choriocarcinoma.

结论 一氧化氮合酶可能在绒毛膜癌的发生、发展过程中起着重要的作用。

37. Conclusion There was a correlation between mycoplasma infection and pathogenesis of RCC.Mycoplasma infection could be a biological factor in the oncogenesis of RCC.

结论肾癌的发生与支原体感染有一定的相关性,支原体感染可能是肾癌的生物学致病因素。

38. Effect of Vitamin A on oncogenesis of nephroblastoma in rats

维生素A对大鼠肾母细胞瘤发生影响的实验研究

39. These results establish a role for BC1 in oncogenesis and cell survival and also demonstrate a potential strategy for cancer therapy.

综而言之,这些结果证实BC1与致癌能力及细胞存活能力有关,同时也证实BC1具有发展抗癌药物的潜能。

40. Expression of RTN gene and its role in oncogenesis of human hepatocellular carcinoma

肝癌组织中内质网蛋白基因表达及其功能的初步研究

41. oncogenesis or development

肿瘤发生发展

42. Effect of spleen tyrosine kinase expression re-activation by inhibition of DNA methylation on oncogenesis growth of gastric cancer

脾酪氨酸激酶基因的再激活对胃癌生成和发展的影响

43. We hope our studies can provide new insights in the understanding of stem cell maintenance, differentiation, oncogenesis and benefit the clinical applications of stem cells.

藉由这些研究,我们期望能促进对细胞学及发生学的瞭解,及干细胞在临床中的应用。

44. Keywords radiation oncogenesis;cellular model;differential expression gene;SSH;novel gene clone;

辐射致癌;细胞模型;差异表达基因;抑制差减杂交;新基因克隆;

45. The results provided data for the study on HPV virological oncogenesis of the oral Cancers.

这一结果为开展口腔癌的HPV病因学研究提供了参考资料。

46. (3) Cell Proliferation, differentiation, apoptosis and roles of their disorders in oncogenesis.

(3)细胞增殖、分化与凋亡紊乱与肿瘤的关系:主要介绍这些细胞生命活动的基本规律及其分子机制,在肿瘤发病学和治疗学上的意义;

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