opioid

opioid

1. 1 Plasma opioid peptides: The DYN and L - EK of MN0.05 group are higher than M group in both 6h and 12h;

1阿片肤变化:MN005组DYN及L一EK在术后6h、24h均高于M组;

2. The aim of their polydrug abuse was alleviating some withdrawal symptoms, reinforcing opioid euphoria and opioid efficacy.

94.2%的阿片类滥用者为同时合用非阿片类药物的多药滥用者,合用的药物以三唑仑、地西泮、曲马朵为主。

3. The opioid receptors (MOR, DOR, KOR) mRNA expression of EA group was considerabl higher than that of model group (P <0. 01) .

EA组炎症局部阿片受体(MOR、DOR、KOR)mRNA表达明显高于模型组的阿片受体mRNA的表达(P<0.01)。

4. The FDA has received reports of doctors and other health care professionals prescribing fentanyl patch for post-surgical pain, headaches, and for mild pain - for patients who are not opioid tolerant.

FDA已接到报告，医生及其他医疗专业人士的处方芬太尼贴片为术后疼痛，头痛，并为轻度疼痛-为病人不阿片宽容。

5. Effects of L-tetrahydropalmatine on opioid peptides contents in morphine dependent rats

L-四氢巴马汀对吗啡依赖大鼠阿片肽含量的影响

6. Till now, Mu opioid receptor's DNA and genomic DNA of human, mouse and pig were cloned in many laboratories in the world.

Mu阿片受体cDNA由我国学者于雷最先成功克隆,到目前为止,世界上已有多个试验室克隆到人、鼠和猪的Mu阿片受体的cDNA和基因组DNA。

7. Actions of NO/NOS system are involved in the activation of opioid receptors.

NO/NOS系统作用与阿片受体的激活相关;

8. The results suggest that Y1 receptor may mediateNPY-induced anti-nociception, and that the opioid receptors in PAG may also be involved in this process in mononeuropathic rats.

NPY引起的PWLs增加可被Y1受体拮抗剂和阿片剂所阻断.结果提示,在大鼠PAG 微量注射NPY可产生明显的镇痛作用.

9. One patient was identified as showing significant scoliotic progression following implantation of an intrathecally placed opioid pump.

一例病人确定为，在鞘内放置阿片肽泵治疗慢性腰痛后脊柱侧弯进展。

10. Like opioid receptors, N-type calcium channels occur throughout the nervous system.

一如鸦片类受体，N型钙离子通道也分布在整个神经系统。

11. Separating and Purification of a New Opioid Peptide

一种新阿片肽的分离纯化

12. These results suggest that opioid pep--tides predominantly reduce synaptic transmission in NAcc.

上述结果提示:在伏核内,阿片肽的作用在于降低突触传递。

13. Unfortunately, opioid receptors are present on neurons throughout the body, including in the brain and the gastrointestinal system.

不幸的是，全身上下包括脑及胃肠道系统里的神经元，都带有鸦片类受体。

14. Opioid peptide derived from milk

乳源阿片肽

15. Main bioactive peptides derived from milk proteins are opioid peptides, antihypertensive peptides, immunomodulatory peptides, antithrombotic peptides and caseinophospho peptides.

乳蛋白是许多生物活性肽的重要来源,主要的乳蛋白源生物活性肽有阿片样肽、降血压肽、免疫刺激肽、抗血栓肽和酪蛋白磷酸肽。

16. Relationship between endogenous opioid peptides and parturient's perception of pain during parturition

产妇内源性阿片肽与正常分娩疼痛的关系

17. The existence of Endogenous Opioid Peptide (EOP) has been known for a long time, and it has been recognized that EOP has a central paregoric effect and can regulate cardiovascular functions.

人们早已知道内源性阿片肽（Endogenous Opioid Peptide，EOP）及阿片受体的存在，并已认识到其在中枢镇痛、中枢心血管功能调节等方面的作用。

18. Keywords Panaxatroil;Radioprotection;Opioid peptides;Immune paramaters;

人参三醇组甙;辐射防护;阿片肽;免疫参数;

19. Pain and Regional Anesthesia Imaging Human Cerebral Pain Modulation by Dose-dependent Opioid Analgesia: A Positron Emission Tomography Activation Study Using Remifentanil.

人类通过剂量依赖性的阿片镇痛产生的大脑疼痛调制成像:一项瑞芬太尼的正电子扫描研究。

20. They had been taking antidepressant medication, tricyclic antidepressants, anti-epileptic medications, and opioid analgesics.

他们已经服用了抗抑郁剂药物、三环抗抑郁药、治疗癫痫的药物，和鸦片类止痛剂。

21. The aboe discussion on the relatiely late proliferation of opioid receptors and the primarily postnatal deelopment of inhibitory controls to spinal cord transmission, would lead most to conclude that opioids hae little impact on the fetus.

以上关于阿片受体较晚形成和抑制控制功能出生后方可形成的讨论，很容易得出这样的结论：阿片剂对胎儿影响很小。

22. Subsequently, symptoms can be relieved with analgesics, including acetaminophen, NSAIDs, or opioid narcotics.

以后，镇痛剂，包括扑热息痛、非类固醇抗炎药或阿片类麻醉剂，都可用于缓解头痛症状。

23. For total intraenous anesthesia, a continuous infusion of a short-acting opioid, such as remifentanil, can be administered along with an infusion of propofol.

全静脉麻醉时，可以采用短效类阿片类药物如瑞芬太尼与异丙酚同时输注。

24. Keywords Morphine;C-fiber;Hippocampal CA1;LTP;Opioid receptor;

关键词吗啡;C-类纤维;海马CA1区;长时程增强;阿片受体;

25. Sixteen of the studies included data on postoperative opioid requirements. In 12 of these studies, gabapentin use was associated with a significant reduction in opioid use.

其中有16项研究涉及到术后阿片类镇痛药的使用，这当中有12项研究提示加巴喷丁的使用的同时，术后阿片类镇痛药的用量减少。

26. Other steps include improving the provision of pain relief for cancer patients, particularly opioid analgesics, which are hardly used in developing countries.

其它步骤包括改善癌症病患的疼痛控制，特别是鸦片类止痛剂，这在开发中国家难以被使用；

27. Patients with persistent pain who require prolonged opioid therapy have little to no risk of developing addictive disease just because they are taking pain medications every day.

其实，那些因持续性疼痛而需要长期服用阿片类药物的患者，仅仅因每天服用这类止痛药而成瘾的风险微乎其微。

28. Keywords endomorphin 1;vasodepression;opioid receptor;central M cholinoceptor;

内吗啡肽-1;降血压作用;阿片受体;中枢M受体;

29. Keywords Endomorphins;Opioid receptor;Blood-brain barrier （BBB）;Stability;Antinociception;

内吗啡肽;阿片受体;血脑屏障;稳定性;镇痛;

30. Endotoxin Inhibits Orphan Opioid Receptor Gene Expression in Peripheral Blood Lymphocyte

内毒素抑制人外周血淋巴细胞孤啡肽受体基因的表达

31. endogenous opiate(opioid)peptide

内源性阿片[样]肽

32. The mechanisms of endogenous opioid peptides participate in the modulation of pain information

内源性阿片肽参与痛信息调控的机制

33. Experimental study of endogenous opioid peptides participating in the fetal distress Hu Dian

内源性阿片肽参与胎兔窘迫过程的实验研究

34. Side-effects common to all drugs in the opioid class include nausea, omiting, and the potential for significant respiratory depression.

副作用和所有阿片类药物一样包括恶心、呕吐、潜在的呼吸抑制。

35. Contractive responses of arterial strips evoked by electric field stimulation were distinctly enhanced after treatment of arte- rial strip with naloxonc, an opioid receptor blocker, and pronase, but unchanged after treatment with trypsin.

动脉条用阿片受体阻断剂纳洛酮或链霉蛋白酶处理后,电场刺激引起的动脉条收缩反应显著增大,但胰蛋白酶无影响。

36. A Daptation of Opioid Receptor and Noradrenergic Neurons During Morphine Dependence

吗啡依赖与阿片受体和去甲肾上腺素能神经的适应

37. Vuyk J,Mertens MJ,Olofsen E,et al.Propofol anesthesia and ration opioid selection.Anesthesiology,1997,87L:1549:62.

吴新民,叶铁虎,岳云,等.国产注射用盐酸瑞芬太尼有效性和安全性的评价.中华麻醉学杂志,2003,23:248.

38. In the normal brain and the body of some organs, the existence of endogenous opioid peptides and opioid receptor.

在正常人的脑内和体内一些器官，存在着内源性阿片肽和阿片受体。

39. Under normal circumstances, the role of endogenous opioid peptides in the opioid receptor, regulating a person's mood and behavior.

在正常情况下，内源性阿片肽作用于阿片受体，调节着人的情绪和行为。

40. External beam therapy, opioid analgesics and hormone are effective for pain relief, but with side effects.

外照射、鸦片类止痛药、激素等治疗虽有止痛效果,但副作用较大;

41. Duragesic, for patients experiencing moderate to severe chronic pain, contains fentanyl, an opioid that could lead to problems such as respiratory depression and fatal overdose.

多瑞吉，用于中等强度或严重的慢性的疼痛患者，包含芬太尼，一种阿片样物质，可能导致像呼吸抑制和过量致死等问题的发生。

42. a natural brain opiate.Also called opioid

天然镇脑剂也作

43. THE EAR ACCUPOINT ELECTRIC RESISTANCE OF 99 TAIYUAN PATIENTS WITH PROTRACTED OPIOID WITHDRAWAL SYNDROME

太原市99例阿片类稽延性戒断综合征耳穴电阻研究

44. Controlled-release oxycodone is a long-acting opioid analgesic drug.

奥施康定是羟可酮的即释型与控释型的结合制剂,是阿片类长效止痛药。

45. She predicts that methadone will have similar effects in other cancers that express opioid receptors.

她预言美沙酮在表达阿片受体的其他肿瘤也会有类似的作用。

46. Endorphins, a known substances produced in brains is an opioid receptor agonist which the brain produce in the presence of pain stimulus.

如果你一连几天、一天几次进行实验：诱发某人身感疼痛，再用吗啡为他止疼，到最后一天，悄悄用盐水取代吗啡，你会发现，此时盐水也能止痛。

47. If, howeer, the score on the monitor of anesthetic depth remains within the range for general anesthesia, the response would be to gie an opioid for pain.

如果评分在全麻范围内，处理就是给予阿片类药物镇痛。

48. Nociceptin/orphanin FQ (N/OFQ) is the endogenous ligand of the opioid receptor-like 1 receptor (NOP), the G-protein coupled receptor which shows overall 60% homology with the classical opioid receptors.

孤啡肽(Nociceptin/Orphanin FQ,N/OFQ)是阿片受体样受体(Nociceptin/orphanin FQ receptor,NOP receptor)的内源性配基。

49. As for the former, the combination of propofol with an opioid, such as remifentanil or fentanyl, will proide required analgesia.

对于前者，联合使用阿片类药物如瑞芬太尼和芬太尼可以提供需要的镇痛。

50. Opioid Activity and Molecular Weight Distribution of Wheat Gluten Oligopeptides

小麦面筋蛋白功能短肽的阿片活性及其相对分子质量分布的研究

51. The complexity of the effect of opioid on memory reflects the variety of interactio...

尽管目前仍有争论,但有关这方面的研究已经取得了较大进展。

52. Enkephalin which belongs to the endogenous opioid peptide family plays an important role in the modulation of dental pain transmission.

属内源性阿片肽家族的脑啡肽在牙疼痛信号的传导和调控中有重要作用。

53. What is known regarding opioid modulation of spinal pain pathways?

已知的脊髓疼痛通路的阿片调节作用。

54. When opioid medications are used, there is an underlying worry about the risk for addiction.

当鸦片类药物被作为止痛药使用时，成瘾的风险不禁让人担忧。

55. A number of common therapeutic pitfalls await emergency care doctors who manage acute pain, including poor analgesic selection, opio;hobia, analgesic underdosing, improper frequency, and the use of unnecessary opioid adjuncts.

急诊医师在处理性疼痛的时候常犯种种的谬误譬如止痛剂的不当选择，担心成瘾，止痛剂量不足，不当的给药途径，不适当的给药频率，以及多馀的附加药剂。

56. Recurrent Hypoxemia in Young Children with Obstructive Sleep Apnea Is Associated with Reduced Opioid Requirement for Analgesia.

患有阻塞性睡眠呼吸暂停的年幼儿童再次发生低氧血症与镇痛所需阿片药物减少有关。

57. Pathophysiologic changes of colonic opioid receptors in slow transit Constipation

慢传输性便秘结肠阿片受体的病理生理改变

58. The possibility of the Kappa opioid receptor (KOR) gene as the candidate gene affection the stereotyped behavior traits in sows was discussed in the current study.

摘要 行为规癖是母猪一种常见的异常行为，表现为重复、不变化的行为模式，并且不带有明显的目的性。

59. The modulation of RGS protein on opioid receptor and adenyl cyclase;

摘要本文介绍了RGS蛋白对阿片受体-腺苷酸环化酶活性的调节；

60. Opioid dependence is a chronic, repeated relapsing disease in brain.

摘要阿片依赖是一种慢性、反复发作性脑疾病。

61. nerve stimulation opioid peptide

放射免疫分析法

62. This study explored opioid analgesics consumption and related factors in hospitalized cancer patients .Cross-sectional design is used in is study .

故本研究旨在瞭解住院癌症病患其鸦片类止痛剂消耗量及探讨影响住院癌症病患鸦片类止痛剂之因素。

63. Role of peripheral mu opioid receptors was studied by the electrical stimulation test of muscle strips and radioreceptor assay.

方法 以“泻剂结肠”为模型 ,用电刺激离体肌条收缩反应试验、放射性配体结合等方法。

64. Antinociceptive Effect of Morphine, but Not? Opioid Receptor Number, Is Attenuated in the Spinal Cord of Diabetic Rats Chen S-R, et al.

是吗啡的抗伤害作用,而非阿片受体的数目在糖尿病性大鼠的脊髓中降低。

65. Recent inestigation into opioid analgesic mechanisms in the fetus and neonate suggest that there are differences before and after birth (1).

最近关于胎儿和新生儿阿片镇痛机制的研究表明：出生前后有所不同[1]。

66. Administration of corticosteroid or injection of local anesthetic agent has been additie treatment methods for opioid drugs.

服用皮质类固醇激素或者局部注射麻醉剂已经成为阿片类药物的辅助治疗方法。

67. This review focuses on the changes in hypothalamic-pituitary-adrenal axis in opioid dependence,withdrawal and relapse,and the relationship between HPA axis and opioid addiction.

本文综述了阿片类物质依赖、戒断和复吸各个阶段下丘脑-垂体-肾上腺皮质轴的改变,及其与阿片依赖、戒断和复吸的关系。

68. This review focuses on the changes in hypothalamic-pituitary-adrenal axis in opioid dependence, withdrawal and relapse, and the relationship between HPA axis and opioid addiction.

本文综述了阿片类物质依赖、戒断和复吸各个阶段下丘脑-垂体-肾上腺皮质轴的改变，及其与阿片依赖、戒断和复吸的关系。

69. In the precent studies,therefore,a series of experimental animal models are designed to investigate the effects of SIN on the opioid withdrawal syndrome and its primary mechanism.

本文通过建立大鼠、小鼠吗啡身体依赖模型及豚鼠回肠身体依赖模型，从整体和离体水平研究了青藤碱对阿片类戒断综合症的抑制作用，并初步探讨了其机制。

70. The Role of Amygdala and Central Opioid Peptide in Somatic Stimulation Induced Inhibition of Central Pressor Response

杏仁及中枢阿片肽在躯体传入冲动抑制中枢性升压反应中的作用

71. Yang CC, Lin TB, Kao YJ, Tsai WJ. An overview of abstinence therapy for opioid addicts. Clin Med (Taipei) 33: 252-61.

杨振昌、林肇柏、郭渊进、蔡维祯。浅谈鸦片类药物毒瘾之药物戒断疗法。临床医学33(4):252-261.

72. Woodhouse A ,Mather LE.The influence of age upon opioid analgesic use in the patient-controlled analgesia (PCA) environment.Anaesthesia, 1997 ,52:949.

欧阳葆怡.椎管内注入镇痛药后的严重并发症--呼吸中枢抑制.国外医学麻醉学与复苏分册,1984,5(6):267-270.

73. Moreover, new receptor system such as opioid and vanilloid receptors on cutaneous sensory nerve fibers were revealed that may modulate itch and thereby represent targets for antipruritic therapy.

此外，在皮肤感觉神经纤维也发现有阿片样肽、香草基衍生物等瘙痒介质的受体存在，提示这些介质可能通过与皮肤感觉神经纤维的受体结合介导瘙痒。

74. Single Nucleotide Polymorphism in Exon Partial Sequence of Sow Kappa Opioid Receptor Gene

猪Kappa阿片受体基因外显子部分序列单核苷酸多态性分析

75. Single Nucleotide Polymorphism Analysis in Sow Mu Opioid Receptor Gene

猪Mu阿片受体基因单核苷酸多态性分析

76. A survey on 155 opioid abusers and their polydrug abuse was carried out with a questionnaire designed by National Institute on Drug Dependence.

用北京医科大学中国药物依赖性研究所设计的调查表,对155例阿片类滥用者及其多药滥用情况进行调查。

77. Oxytocin and endogenous opioid peptide during electroacupuncture analgesia: Is it a synergistic action

电针镇痛过程中催产素与内源性阿片肽:是否协同作用

78. Keywords nociceptin;kappa opioid receptors;bronchi;smooth muscle;guinea pigs;electric stimulation;

痛啡肽;k-阿片受体;支气管;平滑肌;豚鼠;电刺激;

79. Daidzein i. S. C implantation and its effects on opioid receptor in hypothalamus of the pig

皮下埋植大豆黄酮对猪下丘脑阿片肽受体水平的影响

80. The previous studies suggested that endogenous opioid peptides (EOP) participate in the peripheral mechanism of electro-acupuncture (EA) analgesia for inflammatory-pain.

目前,电针(EA)对慢性痛(如炎症痛)的镇痛作用及其外周机制的研究正越来越受到学者们的重视。 以往的研究表明,内源性阿片肽(EOP)参与了EA对炎症痛镇痛的外周机制。