pluripotent

pluripotent

1. "Once the safety issue is overcome, human-induced pluripotent cells should be applicable in regenerative medicine," Kyoto University researcher Kazutoshi Takahashi and colleagues note in their report.

"一旦安全问题，是克服，人为因素引起的多能细胞，应适用在再生医学" ，日本京都大学研究员高桥一俊和他的同事注意到，在他们的报告。

2. In 2007 researchers generated induced pluripotent stem cells from humans after discovering that the same four genes that reprogrammed mouse cells could also reprogram human cells.

2007年，科研人员发现能够重新编程小鼠细胞的四个基因同样能够重新编程人体细胞，并利用人体细胞制成了诱导多功能干细胞。

3. ES cells are pluripotent cells derived from pre - implanted embryos.

ES细胞是由着床前胚胎中分离获得的胚胎多能干细胞。

4. pluripotent cells

[医] 多潜能细胞, 多种作用细胞

5. virus pluripotent

[医] 多能病毒

6. ,Ichiska, T,.&Yamanaka, S.Generation of germline-competent induced pluripotent stem cells.

[已解决求助]求nature文献一篇：Okita,K.

7. OBJECTIVE: Paroxysmal nocturnal hemoglobinuria(PNH) is an acquired disease of the pluripotent hematopoitec stem cell.

[目的] 阵发性睡眠性血红蛋白尿症(PNH)系后天获得性干细胞克隆性异常，临床表现为间断溶血、静脉血栓及不同程度的骨髓衰竭。

8. Dr Xiao said: "Pig pluripotent stem cells would be useful in a number of ways, such as precisely engineering transgenic animals for organ transplantation therapies.

“例如，为了应对猪流感，我们可以培育出一种准确的转基因猪，从而改善它对这种疾病的耐性。我们首先可以找到一种具有抗猪流感活动或者抑制猪流感病毒增殖的基因；

9. "Pig pluripotent stem cell lines could also be used to create models for human genetic diseases.

“猪多能干细胞系还可以用于建立人类遗传病的模型。

10. These cells were pluripotent and ES-like cells.

上述表明该细胞具有多能性，类似ES细胞。

11. The paper reported here the isolation of rabbit pluripotent ES-like cells from PGCs of15-28dpc (day post coidum) ftuses of NZW, SBR and DEB rabbits.

与经典胚胎干细胞的分离路线不同，原生殖细胞（Primordial Germ Cells，简称PGCs）作为胚胎干细胞分离的新型材料是1992年由Resnick和Matsui分别独立在小鼠上率先采用并取得成功。

12. Perhaps the most far-reaching potential application of human pluripotent stem ce lls is the generation of cells and tissue that could be used for so-called “cel l therapies.

也许人体多能性干细胞最深远的潜在用途是产生细胞和组织，它们可用于所谓的“细胞疗法 ”。

13. That proves the cells are, indeed, pluripotent;in other words, they can turn into a variety of tissues.

事实证明细胞是多功能的，换句话说，它们可以转化为各种组织。

14. postembryonic pluripotent stem cell

亚全能干细胞

15. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

人体细胞成功诱导为干细胞

16. Human embryonic stem cells are theoretically capable of differentiation to all cells of the mature human body (and are hence defined as "pluripotent").

人类胚胎干细胞理论上能分化呈成熟人体的所有细胞（因此定义为“多能性”）。

17. Several problems in studying human embryonic pluripotent stem cells

人胚胎多能干细胞研究中的几个问题

18. It is the first time that an induced pluripotent stem (iPS) cell line has been created from a patient with a genetic illness (J.

从患有遗传疾病的患者身上创造出可诱导的多能性干细胞株尚属首次(J.

19. They specialize into pluripotent cells that can give rise to most, but not all, of the tissues necessary for fetal development.

他们存在于多功能性的细胞中，促使这些细胞分化成绝大多数对婴儿的成长有着重要作用的组织（但不是全部）。

20. But to make a true clone a cell needs to be not just pluripotent, but totipotent and thus able to turn into an entire animal.

但是为制作真正的克隆，一个细胞不仅要是多功能的，还必须是全能的，进而能转化成完整的动物。

21. But pluripotent stem cells such as the embryonic cells are difficult to make, requiring the use of an embryo or cloning technology.

但是象胚胎干细胞这样的多能干细胞难以制造,需要使用胚胎技术或克隆技术。

22. But the skin cells were regressed using a method which caused tumors and the potential for genetic mutation, which meant those induced pluripotent stem cells, or iPS, were not safe for clinical use.

但采用一种方法可使皮肤细胞退化，而该方法可导致肿瘤和潜在的基因变异，这意味着这种诱导的多能干细胞或ips使用于临床是不安全的。

23. The use of somatic cell nuclear transfer (SCNT) may be another way that pluripot ent stem cells could be isolated.

体细胞核转移（SCNT）的使用可能是分离出多能性干细胞的另一种途径。

24. Evans M J, Kaufman M H. Establishment in culture of pluripotent cells from mouse embryos[J] . Nature, 1981,292(5819): 154.

何志旭,黄绍良,李予,等.人胚胎干细胞系的初步建立[J].中华医学杂志,2002,82(19):1314.

25. "Those problems could be circumvented if pluripotent cells could be obtained directly from the patients' own cells.

假如能够直接采集到患者自身的多能性细胞，这些问题都迎刃而解了。

26. Keywords umbilical cord blood;Pluripotent stem cells;mononuclear cells;cell differentiation;

关键词脐血;多潜能干细胞;单个核细胞;细胞分化;

27. Effect of early wound fluids on proliferation and migration of dermal pluripotent stem cells

创伤早期伤口液对体外培养真皮多能干细胞增殖迁移特性的影响

28. Cryopreservation ofhumanembryonic stemcellsby vitrification Pluripotent Embryonic Stem Cells Developed into Medulloepithelioma in Nude Mice Eyes

动物胚胎干细胞的建立与应用

29. Ten years after the discovery of human ES cells, scientists are still working on standardizing procedures for coaxing pluripotent cells to become mature tissue.

发现人体胚胎干细胞10年后，科学家们仍然在将那些引导多能细胞成为成熟组织的步骤标准化。

30. Only be able to successfully into the heart, such as nerve cells, pluripotent stem cells for the treatment of the disease can really.

只有能够成功地分化为心脏、神经等各种组织细胞，多能干细胞才能真正用于治疗疾病。

31. pluripotent state

可塑状态

32. Chen SL, Sha ZX, Ye HQ. 2003， Establishment of a pluripotent embryonic cell line from sea Perch(latelabrax japanicus) blastula embryo.Aquaculture, 218：141-151.

叶寒青，陈松林，刘洋,沙珍霞.表达绿色荧光蛋白的花鲈胚胎干细胞株的建立及其体外分化。

33. Recent Progress in Pluripotent Stem Cells Derived from PGCs in Mammal Species

哺乳动物PGCs用于多能性干细胞培养的研究进展

34. pluripotent stem cell

多(潜)能干细胞

35. Pluripotent -capable of giving rise to most tissues of an organism.

多功能性－能产生机体的大多数组织。

36. Pluripotent cells can generate any cell type, but not an entire organism.

多功能细胞能够分化成任何细胞，却不能生成完整的器官。

37. committed pluripotent stem cell

多向性干细胞

38. Pluripotent stem cells

多潜能干细胞

39. pluripotent cell

多潜能细胞, 多种作用细胞

40. Keywords dermal pluripotent stem cells;wound healing;wound fluid;

多能干细胞;真皮;创伤愈合;伤口液;

41. Pluripotent stem cells, stem cell research is the most cutting-edge.

多能干细胞是目前干细胞研究的最前沿。

42. disease of pluripotent stem cell

多能干细胞病

43. Pluripotent stem cells would allow testing in more c ell types.

多能性干细胞将允许在更多类型的细胞上进行实验。

44. The pluripotent stem cells undergo further specialization into stem cells that a re committed to give rise to cells that have a particular function.

多能性干细胞经历进一步的特异分化，发展为参与生成具有特殊功能细胞的干细胞。

45. Pluripotent means the cells can gie rise to any type of tissue in the body, including blood, nere and muscle.

多能性意味着细胞能生成体内任何组织类型，包括血液、神经和肌肉。

46. "Pluripotent" refers to the ability to differentiate into most other cell types.

多能性是指细胞能够分化为其它各种类型细胞的潜能。

47. pluripotent hemopoietic stem cell

多能性造血干细胞

48. pluripotent virus

多能病毒

49. pluripotent hematopoietic stem cell

多能造血干细胞

50. pluripotent mesenchymal cell

多能间质细胞

51. pluripotent colony forming cell

多能集落生成细胞

52. pluripotent myeloid stem cell

多能髓样干细胞, 多能骨髓干细胞

53. Having such a gene expression profile would not only provide a way of identifying pluripotent ES cells, it would also offer tremendous insight into the properties that confer their “stemness.

如果能有干细胞基因表现的资料，不仅可以用来鑑别多能性胚胎干细胞，也能让我们深入了解这些细胞之所以成为干细胞的条件。

54. Dr.Lindvall: Tumorgenesis is something that we have to solve when it comes to human embryonic stem cells and also these news induced pluripotent stem cells.

对于胚胎干细胞和新型的多能干细胞来说，成瘤性确实是个需要解决的问题。

55. The mechanisms and ways to derivate pluripotent cells were reviewed.

对获得多能性干细胞所涉及的机制以及方法进行了综述。

56. Keywords mouse,embryonic stem cells,chimera,fusion,pluripotent;

小鼠;胚胎干细胞;嵌合体;融合;多能性;

57. Yamanaka's team generated versatile iPS (induced Pluripotent Stem) cells, which, like embryonic stem cells, can develop into various organs and tissues.

山中的团队产生多才多艺新闻通讯社（诱导多能干）细胞，即如同胚胎干细胞，可以发展成各种器官和组织。

58. （Allison D.Ebert, Junying Yu, Ferrill F.Rose, Jr, Virginia B.Mattis, Christian L.Lorson, James A.Thomson, Clive N.Svendsen "Induced pluripotent stem cells from a spinal muscular atrophy patient.

年1月，汤姆森小组再次独辟奇径，利用重症神经疾病患者的皮肤细胞培养出的iPS细胞重分化为神经细胞后，在试管内成功再现了神经细胞因疾病死亡的过程。

59. Understanding the initial developmental status of the different pluripotent lines is critical for defining starting conditions for differentiation toward therapeutically relevant cell types.

弄清这些不同多潜能细胞系的初始发育状态对于制定使其向治疗相关细胞类型分化时的起始条件是非常关键的。

60. When the animal is born, if the marked cells turn up in all its tissues, the cell line is deemed pluripotent.

当动物出生后，如果有标记的细胞出现在所有的组织中，即可认定该细胞株具有多能性。

61. As a fertilized egg starts to divide and grow into a complete organism, the cells in this developing ball of embryo are known as pluripotent stem cells.

当受精卵细胞开始分裂并生长成一个完整的有机体时，生长的胚胎中的这些细胞正是多能性干细胞。

62. Chronic myelogeous leukemia (CML) is a clonal disorder of a pluripotent hematopietic stem cell associated in over 95%of cases with the Ph chromosome.

慢性粒细胞白血病(CML)是骨髓多能造血干细胞恶性增殖性疾病。

63. The resulting induced pluripotent stem cells, or IPS cells, have similar properties to embryonic stem cells.

我们首先可以找到一种具有抗猪流感活动或者抑制猪流感病毒增殖的基因；

64. Abstract : Cellular reprogramming could dedifferentiate somatic cells into pluripotent state, which has tremendous potential in regenerative medicine.

摘 要 ：体细胞通过重编程转变成其他类型的细胞，在再生医学方面具有重要的应用前景。

65. At least two different states representing the epiblast progenitors in the blastocyst and the pluripotent progenitors of the later gastrulating embryo have been recognized.

最少两种代表不同的发育状态已得到确认，一种是胚泡中的外胚层祖细胞，另一种为晚期原胚多潜能祖细胞。

66. We hypothesize that the maintenance of undifferentiation in embryonic stem cells by using small molecules can also make the same effects on those pluripotent adult embryonic-like stem cells.

本文概述了几种小分子物质的最新研究进展，并对小分子物质在成体多分化潜能胚胎样干细胞分化调控方面的应用前景进行评述。

67. Mice implanted with these induced pluripotent stem cells remained tumor free after six months, according to the study published online in Science Express.

根据在线发表ScienceExpress上的研究结果，植入了这种多能干细胞的小鼠在六个月后仍未患肿瘤。

68. Such direct reprogramming, however, might be simpler and safer than using pluripotent cells to treat some diseases.

然而，这种细胞的直接再编程对治疗某些疾病来说，也许比采用多能干细胞更简单、更安全。

69. Isolation of pluripotent stem cells from cultured porcine germ cells

猪胚胎多能性干细胞的分离培养

70. Studies on isolation of pluripotent stem cells from cultured porcine primordial germ cells

猪胚胎干细胞的分离培养

71. Mannose-binding lectin(MBL) is a key component of the innate immune system that plays a pluripotent role in natural defense.

甘露糖结合凝集素(MBL)是先天性免疫系统的重要成分之一,在免疫防御中发挥多重作用。

72. The need to find more reliable markers that distinguish truly pluripotent ES cells is driving widespread attempts to catalogue the genes that are turned on or off at various times in cultured ES cells.

由于需要有更可靠的标记，来辨别真正具有多能性的胚胎干细胞，因此科学家正如火如荼地研究，想为培养的胚胎干细胞在不同时期启动与关闭的基因分门别类。

73. The expression of secretory leukocyte protease inhibitor in dermal pluripotent stem cells

白细胞蛋白酶抑制因子在真皮多能干细胞中的表达

74. Studies in AML have suggested that some human acute myeloid leukemias arise from neoplastic transformation at the level of pluripotent stem cells while others arise at much later stages, leading to a block in cell maturation.

白血病研究提示人急性粒细胞白血病是发生于多向干细胞水平的肿瘤性变,而另一些可发生在晚些阶段致细胞成熟停滞。

75. Presently, there are 3 problems in the study of human embryonic pluripotent stem cells: short of materials, complicacy of culture system and spontaneous differentiation.

目前在人胚胎多能干细胞的研究中存在材料来源不足、培养体系复杂和自发性分化的问题。

76. dermal pluripotent stem cells

真皮多能干细胞

77. Effects of dermal pluripotent stem cells on wound healing

真皮多能干细胞在创伤愈合中的作用

78. Neural stem cells (NSCs) have the properties of extensive self-renewal and pluripotent differentiation.

神经干细胞具有自我更新和多向分化潜能。

79. Progress on the Avian Pluripotent Stem Cells

禽类多能性干细胞研究进展

80. The scientists concluded that at least one cell was pluripotent.

科学家认为至少有一个细胞具有全能性。