thalidomide

thalidomide

1. In 1962 amendments added the requirement that drugs also be proved effective after the worldwide thalidomide furor.

1962年的修正案，则因为1961年发生全球哗然的沙利窦迈事件，而增列证明药物有效的要求。

2. thalidomide child

=thalidomide baby

3. The results show that LD-Arac and Thalidomide therapy, no serious bone marrow refrain and no infection and bleeding,is an effective method in improveing the patient prognosis.

LD-Arac和沙利度胺治疗高危MDS确有明显疗效,无严重骨髓抑制,无感染及出血,明显改善高危MDS病人的预后。

4. To observe the side-effects of thalidomide used for multiple myeloma.

了解沙利度胺治疗多发性骨髓瘤时发生的不良反应。

5. This article summarizes the application and mechanism of action of thalidomide in the treatment of some skin diseases.

介绍了沙利度胺在皮肤病治疗中的应用和作用机制等方面的进展。

6. Sinus bradycardia during therapy for multiple myeloma with low-dose thalidomide

低剂量沙利度胺治疗多发性骨髓瘤致窦性心动过缓

7. an abnormality of development in which the upper part of an arm or leg is missing so the hands or feet are attached to the body like stumps; rare condition that results from taking thalidomide during pregnancy.

先天缺少肢体的上部下部直接长在生体上。

8. an abnormality of development in which the upper part of an arm or leg is missing so the hands or feet are attached to the body like stumps; rare condition that results from taking thalidomide during pregnancy

先天缺少肢体的，上部下部直接长在生体上

9. Cloning would join the unsafe drug Thalidomide in the teratogenic hall of infamy

克隆将作为致畸高手，与不安全药物“反应停”一样，臭名远扬。

10. 3. Cloning would join the unsafe drug Thalidomide in the teratogenic hall of infamy.

克隆将作为致畸高手，与不安全药物“反应停”一样，臭名远扬。收藏指正

11. Systemic thalidomide has good effect on refractory chronic discoid lupus erythematosus(CDLE) whereas topical regimen of it has not been reported previously.

全身应用沙利度胺治疗顽固性慢性盘状红斑狼疮具有较好的效果,但目前国内外尚未见局部使用沙利度胺治疗顽固性慢性盘状红斑狼疮的相关报道。

12. Keywords arsenic trioxide;thalidomide;treatment;chronic myelocytic leukemia;accelerated phase;

关键词亚砷酸;沙利度胺;治疗;慢性髓细胞白血病;加速期;

13. Title： Effect of thalidomide on the growth and angiogenesis of human ovarian epithelial cancer transplanted subcutaneously in nude mice.

关键词：卵巢肿瘤;沙立度胺;肿瘤血管生成;疾病模型,动物

14. Keywords Ovarian neoplasms;Thalidomide;Tumor angiogenesis;Disease models;animal;

卵巢肿瘤;沙立度胺;肿瘤血管生成;疾病模型;动物;

15. Keywords Primary liver cancer;Thalidomide;TACE;Recrudescence;Metastasis;Survival period;

原发性肝癌;沙利度胺;TACE术;复发/转移;生存期;

16. Interventional effects of thalidomide on levels of serum vascular endothelial growth factor in patients with myelofibrosis

原发性骨髓纤维化患者血管内皮生长因子水平变化与反应停的干预

17. Evidence that thalidomide modifies the immune response of patients suffering fro m actinic prurigo

反应停(沙利度胺)调节光化性痒疹患者免疫应答的证据

18. Keywords thalidomide;malignant plasmcyte disease;therapeutics;side effects;

反应停;浆细胞病;治疗学;不良反应;

19. Keywords Thalidomide;drug eruption;analysis;

反应停;药疹;分析;

20. Effect of Thalidomide on the Expressions of Vascular Endothelial Growth Factor in Human Lung Adenocarcinoma Cell Line

反应停对人类肺腺癌细胞系血管内皮生长因子表达影响

21. The effect of thalidomide on blood serum soluble tumor necrosis factor receptor level and its clinical significance in patients with hematological malignancies

反应停对恶性血液病患者血清肿瘤坏死因子受体的影响及临床意义

22. The clinical and experimental study of thalidomide in the treatment of ankylosing spondylitis

反应停治疗强直性脊柱炎的临床与实验研究

23. The Rare Side Effects of Thalidomide in Treating Malignant Plasmacyte Disease

反应停治疗恶性浆细胞疾病时的罕见不良反应

24. thalidomide deformity

反应停畸形:反应停为镇静安眠药物, 妊娠早期孕妇服用可致胎儿耳部和肢体等畸形

25. Therapeutic effectiveness of thalidomide and dexamethasone to multiple myeloma and its side effects

反应停联合地塞米松治疗多发性骨髓瘤临床观察

26. thalidomide embryopathy

反应停胎儿病

27. Thalidomide embryopathy syndrome

反应停胚胎病综合征

28. Can thalidomide play a role in the treatment of SLE?

反应停（镇静剂）能否用于SLE的治疗?

29. Oral thalidomide and cyclosporine can also improve both skin appearance and pruritus in PN.

口服沙利度胺、环孢素也可以改善皮肤状况和瘙痒。

30. In the months that followed, more news about Thalidomide continue to flow in.

后来的几个月里,继续传来有关萨立多胺的消息。

31. In the months that followed, more news about thalidomide continue to flow in

后来的几个月里，继续传来有关酞胺哌啶酮的消息。

32. In this paper, a case of refractory CDLE cured with topical thalidomide in clinic was reported and the feasibility of topical therapy was reviewed.

四川大学华西口腔医院黏膜科局部应用沙利度胺治愈1例顽固性下唇盘状红斑狼疮。

33. We, therefore, attempted a trial of oral Thalidomide and achieved rapid biochemical and cytological remission with a short course.

因此，我们尝试应用口服沙利度胺治疗，患者迅速获得生化和细胞学缓解。

34. Keywords Recurrent epithelial ovarian cancer;Thalidomide;Liposomal doxorubicin;Drug therapy;combination;

复发性卵巢上皮性癌;沙利度胺;脂质体阿霉素;药物疗法;联合;

35. Keywords Multiple myeloma;VAD schema;Thalidomide;M protein;Vascular endothelial growth factor;

多发性骨髓瘤;VAD方案;沙利度胺;M蛋白;血管内皮细胞生长因子;

36. Keywords multiple myeloma;thalidomide;chemotherapy;

多发性骨髓瘤;沙利度胺;化疗;

37. Keywords Thalidomide;Multiple myeloma;Haemostatic function;

多发性骨髓瘤;沙利度胺;止凝血功能;

38. Keywords Multiple myeloma;Thalidomide;Bone marrow stromal cell;ICAM 1;VCAM 1;Vascular endothelial growth factors （VEGF）;Basic fibroblast growth factors （bFGF）;

多发性骨髓瘤;沙利度胺;骨髓基质细胞;细胞间粘附分子;血管细胞粘附分子;血管内皮生长因子;碱性成纤维细胞生长因子;

39. Keywords Multiple myeloma;Thalidomide;Dexamethasone;Previously untreated;

多发性骨髓瘤;沙立度胺;地塞米松;初治;

40. Because thalidomide causes severe birth defects if taken during pregnancy, this drug can only be obtained through a special program run by the drug company that makes it.

如果孕期服用沙立度胺可导致严重的先天性缺陷，这一药物只能通过生产它的药物公司的特殊程序获得。

41. If thalidomide were invented today, it would never be released for human use because new tests on pregnant animals would reveal the dangers.

如果萨力多胺是现在发明的，它就不会被批准为人类使用，因为在有孕的动物身上实验会提示其危险。

42. If thalidomide were invented today, it would never he released for human use because new tests on pregnant animals would reveal the dangers.

如果萨立多胺是今天发明的，它就决不会用在人身上，因为对怀孕的动物的新试验将会发现这种危险。

43. " It has been a tranquilizing Thalidomide, relieving the emotional stress for a moment, only to give birth to an ill-formed infant of frustration.

它不啻起镇静作用的反应停，使紧张情绪放松片刻，却导致沮丧失意感这一畸形儿的产生。

44. Thalidomide: notorious for causing limb defects in children born to mothers taking the drug.

它始用于1957年10月的西德，到1961年，它是西德境内和英国销售最好的助眠药。

45. The famous example of thalidomide is a case for more animal testing, not less.

它证明需要更多的动物实验而不是更少的动物实验。

46. any agent that interferes with normal embryonic development: alcohol or thalidomide or X-rays or rubella are examples

导致畸形胎或畸形的制剂，如病毒、药物或辐射

47. any agent that interferes with normal embryonic development: alcohol or thalidomide or X-rays or rubella are examples.

导致畸形胎或畸形的制剂，如病毒、药物或辐射。

48. Thalidomide in Low Dose

小剂量反应停

49. Keywords Mouse;Hepatoma;H22;Thalidomide;Inhibition of angiogenesis;Apopt osis;

小鼠;肝肿瘤;H22细胞;反应停;血管生成抑制;细胞凋亡;

50. Keywords chronic discoid lupus erythematosus;thalidomide;topical administration;

慢性盘状红斑狼疮;沙利度胺;局部用药;

51. My left arm is a short stub with a small hand and three fingers, reminiscent of a thalidomide defect.

我的左手上面只有三根手指，并且手臂很短小，这让我想起了“停缺损”。

52. Modified VAD regimen combined with thalidomide in treatment of multiple myeloma

改良VAD方案联合沙利度胺治疗多发性骨髓瘤

53. Methods The rare side effects of thalidomide in treating 4 cases of malignant plasmacyte disease were investigated and the pertinent literatures were reviewed.

方法总结应用反应停治疗恶性浆细胞疾病时见到的4例罕见不良反应的患者,并进行相关文献复习。

54. Lenalidomide, a novel analogue of thalidomide, belongs to the immunomodulatory drug (IMiD) for the treatment of multiple myeloma and myelodysplastic syndrome.

来那度胺是一种新型免疫调节药,主要用于治疗多发性骨髓瘤和骨髓增生异常综合征。

55. Lenalidomide is a noel immune modulating, non-chemotherapy, cancer drug that is chemically similar to thalidomide, but is more potent in the laboratory and appears to lack some of the more common side effects of thalidomide.

来那度胺是一种新型的免疫调节剂用来治疗肿瘤，它是非化疗药物，化学结构与反应停相似，但是在实验室研究效果更好，副作用更少。

56. Determination the Content of Thalidomide Capsule by Hydrolyze Method

水解法测定沙利度胺胶囊的含量

57. Keywords thalidomide;acute lung injury;dinoprostone （PGE_2）;protein;oleic acid;

沙利度胺;急性肺损伤;地诺前列酮（前列腺素E_2）;蛋白质;油酸;

58. Keywords Thalidomide;Myelofibrosis;Treatment outcome;

沙利度胺;骨髓纤维化;治疗结果;

59. Thalidomide was first introduced to the market in 1956 as a sedative,but was abandoned soon because it was correlated with severe birth defects.

沙利度胺作为一种镇静剂于1956年上市,但是由于其致畸的副作用而很快被禁用。

60. The outcome and side-effects in patients with malignant plasma cell diseases treated with thalidomide combined with combination chemotherapy

沙利度胺加联合化疗治疗恶性浆细胞疾病的疗效和不良反应

61. Positive Immunoregulation of Thalidomide on Human Peripheral Blood Mononuclear Cell Cultures

沙利度胺对人外周血单个核细胞免疫正调控作用

62. Therapeutic potential of thalidomide and its effect in proinflammatory cytokines in adjuvant-induced arthritis rats

沙利度胺对大鼠佐剂性关节炎的治疗作用及其对炎性细胞因子的影响

63. Effects of thalidomide on the expression of adhesion molecules in experimental hepatic fibrotic rats

沙利度胺对肝纤维化大鼠黏附分子表达的影响

64. Clinical observation of adverse reactions to thalidomide used for multiple myeloma

沙利度胺治疗多发性骨髓瘤及其不良反应的观察

65. Thalidomide and Low-Arac Treatment for 27 cases with High Risk Myelodysplastic Syndromeombination

沙利度胺联合LD-Arac治疗高危骨髓增生异常综合征27例

66. The clinical research of thalidomide incorporation with VAD in treatment of multiple myeloma

沙利度胺联合VAD方案治疗多发性骨髓瘤的临床研究

67. Clinical Study of Thalidomide Incorporation with VAD in Treatment of Multiple Myeloma with Emphasis on VEGF Change

沙利度胺联合VAD治疗多发性骨髓瘤的血清VEGF变化

68. Keywords Thalidomide capsule;Hydrolyze method;Determination of content;

沙利度胺胶囊;水解法;含量测定;

69. Acute arrest of bone marrow produced by thalidomide

沙利度胺致急性骨髓抑制

70. Thalidomide (1954): Drug formerly used as a sedative and to prevent morning sickness during pregnancy.

沙利窦迈 (1954): 过去曾用作镇静剂和妊娠时作为止吐剂使用的药物。

71. Thalidomide (1954): Drug formerly used as a sedative and to prevent morning sickness during pregnancy.

沙利窦迈(1954):过去曾用作镇静剂和妊娠时作为止吐剂使用的药物。

72. Side effects of thalidomide include drowsiness, fatigue, severe constipation, and neuropathy (nerve damage causing pain).

沙力度胺的副反应包括困倦、疲劳、严重的便秘和神经病变（神经受损导致疼痛）。

73. Clinical study of effects of thalidomide on cytokines in patients with multiple myeloma

沙立度胺对多发性骨髓瘤患者细胞因子影响的临床研究

74. Clinical observation on thalidomide accompanied chemotherapy in treatment of patients with refractory or relapsed multiple myeloma

沙立度胺联合化疗治疗难治性及复发性多发性骨髓瘤的临床观察

75. Examples of blood cancer drugs that are taken by mouth are thalidomide, lenalidomide and imatinib mesylate.

治疗血癌的一些口服药物的例子是沙利度胺、来那度胺、伊马替尼。

76. My left arm is a short stub with a small hand and three fingers reminiscent of a thalidomide defect.

然而幸运的是，我有一对极好的父母。

77. Researchers now believe that the birth defect caused by thalidomide, a drug once used to prevent nausea in pregnant women resulted from the "sinister", or left-handed form.

现在，研究人员发现，由一种曾用于防止孕妇恶心的药物酞胺哌啶酮所导致的产怪胎问题，是左旋体作用的结果。

78. the main products are raw materials and intermediate such as ranitidine side3,thalidomide,tdtraisopropyl titanate,1-hydroxybenzotriazole etc.

生产雷尼替丁仙链三等药物原料及基中间体。

79. deformed thalidomide babies; his poor distorted limbs; an ill-shapen vase; a limp caused by a malformed foot; misshapen old fingers.

畸形的镇定剂婴儿；他四肢畸形；难看的花瓶；因足部畸形而一跛一跛地走；苍老变形的手指。

80. 8. deformed thalidomide babies; his poor distorted limbs; an ill-shapen vase; a limp caused by a malformed foot; misshapen old fingers.

畸形的镇定剂婴儿；他四肢畸形；难看的花瓶；因足部畸形而一跛一跛地走；苍老变形的手指。收藏指正