thrombin
thrombin
1. In 1977, the FDA revoked the licenses for all commercially-prepared human thrombin preparations due to high rates of hepatitis B.
1977年，由于B型肝炎的高发生率，美国食品药物管理局吊销了所有商业制造的人凝血脢制剂的许可执照。
2. Utilizing Fura-2 fluorescence indicator, AHF reduced 19.3% of the elevated of Ca 2+ concentration in platelet induced by thrombin in normal elderly ( P<0.05 ).
AHF对凝血酶诱发的老年人血小板内Ca2 + 浓度的增加值可降低 1 9 3% (均P <0 0 5)。
3. The molecular weight of GST-GFP was 53kDa in homonymous to its theoretical size.GFP was purified by using affinity binding and thrombin treatment.
GST-GFP分子量大约为53kDa，与其理论值大小一致，用亲和层析以及凝血酶处理纯化GFP。
4. Role of RhoA in the endothelial cell monolayer permeability induced by thrombin or lipopolysaccharide
RhoA介导凝血酶或脂多糖诱导内皮细胞株单层通透性增高
5. Determination of Thrombin Inhibitor Activity by Absorbance rate of Change
一种测定凝血酶抑制剂活性的新方法
6. a plasma protein that is converted into thrombin during blood clotting
一种血浆蛋白质，在血液凝聚时转化成凝血酵素
7. Determination of thrombin clotting time
七、凝血酶凝固时间测定
8. In contrast to the thrombin group, thrombin plus pentoxifylli ne (PTX) siginificantly decreased the TF activity of astrocytes (P<,0.05).
与凝血酶组比较，已酮可可碱十凝血酶组星形胶质细胞组织因子活性表达明显下降。
9. The preparation of two kinds of affinitive adsorbents in purification of porcine thrombin
两种不同的亲和吸附剂对猪凝血酶纯化效果的比较
10. A Thrombin Inhibitor from Ixodid Tick, Ixodide sinesis
中华硬蜱凝血酶抑制剂的分离纯化与活性
11. Clinical Measures of Heparin's Effect and Thrombin Inhibitor Levels in Pediatric Patients with Congenital Heart Disease.
临床测量肝素钠及凝血酶抑制剂的水平对充血性心衰的儿科病人的作用。
12. By chromatography and the detection of inhibition enzyme activity, a few kinds of trypsin inhibitors and thrombin inhibitors were found in the water bloom from Taihu Lake.
为配合太湖蓝藻的收集处理,研究了蓝藻水华的资源化可能,在前期工作的基础上,通过层析分离并结合活性测定,发现太湖蓝藻水华中有多种胰蛋白酶和凝血酶抑制剂
13. Comparatively,BDA effected stronger on thrombin time (TT) but BDBeffected more on prothrombin time(PT).
二者相比较,BDA 的凝血酶时间(TT)的作用较BDB 更为显著,而BDB 凝血酶原时间(PT)的作用强于BDA。
14. THE EFFECT OF CHANGING BODY POSTURE ON THROMBIN ACTIVITY AND CONCENTRATION
人体位改变对凝血因子某些因素水平的影响
15. Keywords lyophilized human thrombin;accelerated test;stability;hemostatic;
人凝血酶;加速试验;稳定性;止血药;
16. The content of hypoxanthine in Hirudo was measured by high performance liquid chromatography(HPLC)and Hirudin was determined by thrombin.
以凝血酶法测定水蛭素的含量;以HPLC测定次黄嘌呤的含量。
17. Purification of Porcine Thrombin by Affinity Chromatography Using Chitosan Porous Beads as Support
以壳聚糖多孔珠作为亲和吸附剂载体分离纯化猪凝血酶的研究
18. Chaikaf C,Matthews D,Appelbaun F,et al.Growth-related responses in arterial smooth muscle cells are arrested by thrombin receptor antisense sequence[J].J Biol Chem,1995,270:7431.
任国峰,王宗立,李拥军,等.反义凝血酶受体基因的构建其对主动脉血管平滑肌细胞增殖的影响[J].基础医学与临床,2000,20:47.
19. In vitro,argatroban could inhibit other roles of thrombin,such as tumor cell metastasis,inflammation and restenosis after angioplasty.
体内外研究表明,它还抑制凝血酶的其他作用,如可以抑制肿瘤转移、炎症过程及血管成形术后的再狭窄等。
20. As a direct thrombin inhibitor, recombinant hirudin(r-hirudin) has played an important role in clinical use.
作为直接凝血酶抑制剂,重组水蛭素在临床上的应用已越来越重要。
21. Keywords bombyx Botryticatus;vascular endothelial cell;thrombin;
僵蚕注射液;血管内皮细胞;凝血酶;
22. Keywords thrombin;gelatin sponge;brain edema;
关键词凝血酶;明胶海绵;脑水肿;
23. Keywords astrocytes;thrombin;oxygen-glucose deprivation;glutamate uptake;
关键词星形胶质细胞;凝血酶;氧糖剥夺;谷氨酸摄取;
24. Keywords leech;retinal pigment epithelium;RPE;thrombin;
关键词水蛭;视网膜色素上皮细胞;凝血酶;
25. Keywords Hypertomic saline Reptilase Endoscopic injection Thrombin;
关键词高渗盐水;立止血;内镜下注射;凝血酶;
26. The endogenous thrombin is a kind of neurotoxic agent which causes a series of pathophysiological changes.
内源性凝血酶是一种神经毒性物质,可引起脑组织一系列的病理生理学改变。
27. Antithrombotic effect of recombinant human thrombomodulin on thrombin induced thromboembolism in mice.
内皮细胞因子在新生儿肺损伤中起了重要作用。
28. An enzyme, such as rennin or thrombin, that induces coagulation.
凝固酶能引起凝固作用的一种酶，如凝乳酶和凝血酶
29. A plasma protein that is converted into thrombin during blood clotting.
凝血原酶一种血浆蛋白质，在血液凝聚时转化成凝血酵素
30. Factor X is activated, which combines then with factor V to generate thrombin.
凝血因子X激活后和凝血因子V结合形成纤维蛋白酶。
31. We found that, while induced the increase of WPB release by 3-fold in HAEC, thrombin (1 unit, 30 min) resulted in the increase of activation of Rac-GTP binding activity by 3.5-fold, and increase of ROS production by 3.4-fold.
凝血酶 (1单位 ,30min)介导WBP释放增加 (较基础值增加了 3倍 )的同时 ,使Rac GTP结合活性及ROS分别增加了 3 5倍和 2 4倍。
32. Keywords Thrombin;Mechanism of Clot;Prothrombin;Activation;
凝血酶;凝血机制;凝血酶原;激活;
33. Keywords thrombin;platelet-rich plasma;bone marrow stomal cells;cell proliferation;
凝血酶;富血小板血浆;骨髓基质细胞;细胞增殖;
34. Keywords thrombin;astrocyte;hypoxia/reoxygenation;hirudin;
凝血酶;星形胶质细胞;缺氧/复氧;水蛭素;
35. Keywords thrombin;hirudin;intercellular adhesive molecules;
凝血酶;水蛭素;细胞黏附分子;
36. Keywords thrombin;thromboembolism;heparin;fibrinolysis;
凝血酶;血栓;肝素;纤溶;
37. Keywords Thrombin;Intracranial pressure;Intracerebral hemorrhage;
凝血酶;颅内压;脑出血;
38. Thrombin and malignancy of lung
凝血酶与肺部恶性肿瘤
39. The purified recombinant TSP2HD protein was obtained through digesting the GST-TSP2HD fusion protein with thrombin.
凝血酶切割GST-TSP2HD融合蛋白获得纯化的重组TSP2HD蛋白。
40. Thrombin stimulates HMC to produce ET 1 and ET 1 mediates the HMC proliferation.
凝血酶刺激HMC产生ET?1，ET?1介导了HMC增生。
41. Irreversible inhibitor of Thrombin and other serine proteases. Inhibits by acylation of the active site of the enzyme. Much less toxic than PMSF and DFP.
凝血酶及其他丝氨酸蛋白酶的不可逆抑制剂，将活性位点酰基化。比PMSF和DFP毒性小得多。
42. Keywords Thrombin receptor;Antisense RNA;Restenosis;Smooth muscle cell proliferation;Polymerase chain reaction;
凝血酶受体;反义RNA;再狭窄;平滑肌细胞增生;聚合酶链反应;
43. thrombin increasing fibrinopeptide B
凝血酶增强纤维蛋白肽B
44. Enhancement of NMDA receptor sensitivity by thrombin and its relationship with tissue transglutaminase
凝血酶增高NMDA受体敏感性与组织型谷氨酰胺转移酶的关系
45. Effects of Thrombin on Blood Brain Barrier, Water and Ion Contents of Thalamic Tissue
凝血酶对丘脑组织血脑屏障及水电解质含量的影响
46. Dynamic study on damage of nerve cell DNA in caudate nucleus induced by thrombin in rats
凝血酶对大鼠尾状核区神经细胞DNA损伤的动态研究
47. Effect of thrombin on the permeability of blood brain barrier and study of the brain cell apoptosis mechanism
凝血酶对血脑屏障通透性的影响及细胞凋亡机制的研究
48. Advances in the Research on Thrombin Inhibtor
凝血酶抑制剂研究进展
49. inhibitory factor of thrombin
凝血酶抑制因子
50. thrombin antithrombin Ⅲ complex
凝血酶抗凝血酶Ⅲ复合物
51. Determination of r-Hirudin Concentration in the Plasma of Rabbits by Thrombin Time Method
凝血酶时间法测定家兔血浆中重组水蛭素
52. Thrombin clotting time measurement of plasma heparin and its clinical application
凝血酶法测定血浆肝素含量及其临床应用
53. Thrombin activatable fibrinolysis inhibitor (TAFI)
凝血酶活化的纤溶抑制剂
54. Fibrinolytic inhibitory substance activated by thrombin
凝血酶激活的纤溶抑制物
55. Endogenous thrombin generation
凝血酶生成潜力
56. Affinity Chromatography Technique for the Thrombin Purification
凝血酶的亲和层析纯化技术
57. Progress in Studies of Thrombin
凝血酶的研究进展
58. Neurotoxic effect of thrombin :proved by MRI in rats
凝血酶神经毒性作用的在体mri观察
59. Thrombin is an enzyme that catalyzes the conversion of the soluble plasma protein fibrinogen to the insoluble protein fibrin.
凝血酶能催化可溶性血浆纤维蛋白转化为不溶性的纤维蛋白。
60. Thrombin converts Protein C into activated protein C(APC).
凝血酶能将蛋白C转化为活化蛋白C(APC);
61. Thrombin induced coagulation
凝血酶诱发血凝固
62. The secretion and activation of gelatinase induced by thrombin in cultured human embryonic vascular smooth muscle cells
凝血酶诱导人类胚胎血管平滑肌细胞明胶酶分泌及活化
63. Thrombin promoted proliferation of mesangial cells, and enhanced the expression of ICAM1, MMP2, and MMP9 in mesangial cells.
凝血酶还可以促进系膜细胞增殖、表达ICAM－1、纤溶酶原激活物抑制物－1（PAI－1）、基质金属蛋白酶－2（MMP－2）及基质金属蛋白酶－9（MMP－9）。
64. thrombin sensitive protein(TSP)
凝酶敏感蛋白
65. Zain J,Huang YQ,Feng XS,et al.Concentration-dependent dual effect of thrombin on impaired growth/apoptosis or mitogenesis in tumor cells[J].Blood,2000,95:3133.
刘春梅,史宝柱,吴家幂.凝血酶致实验性脑出血继发性损伤的炎性机制及其干预研究[J].临床神经病学杂志,2004,17:275.
66. Intracerebral infusion of thrombin as a cause of brain edema after brain contusion in rats
创伤性脑损伤病灶中的凝血酶对脑水肿的影响
67. Predicting the stability of lyophilized human thrombin by accelerated storage test
加速试验估算人凝血酶冻干品的贮存寿命
68. Keywords Femoral arter;Pseudoaneurysms;Ultrasonography;Thrombin;
动脉瘤;假性;股动脉;超声检查;凝血酶;
69. Keywords Atherosclerosis;Thrombin activatable fibrinolysis inhibitor （TAFI）;Endothelium injuries;
动脉粥样硬化;凝血酶活化的纤溶抑制剂;内皮损伤;
70. The effect of infusing thrombin into pleural cavity for treatment of malignant pleural effusion
博来霉素联合凝血酶对恶性血性胸水的疗效观察
71. Keywords piezoelectricity;quartz crystal;sensor;thrombin time;
压电;石英晶体;传感器;凝血酶时间;
72. Construction and Preliminary Application of Piezoelectric Quartz Crystal Sensor for Detecting Plasma Thrombin Time
压电石英晶体凝血酶时间检测传感器的构建及初步研究
73. Simultaneously, the thrombin system in the blood sets off a series of reactions that produces long, stretchy proteins.
同时血液中的凝血酶系统开始一系列的反应，生成长形的、有弹性的蛋白质。
74. Similarly, fluorescent thrombin bound ubiquitously on the surface of fibrin clots, overlapping slightly with PS-exposing platelets.
同样，荧光凝血酶约束无所不在表面的纤维蛋白凝块，重叠略有聚苯乙烯揭露血小板。
75. Keywords Eupolyphaga sinensis;Hirudo nipponia;Anticoagulant activity;Thrombin;
土鳖虫;日本医蛭;抗凝活性;凝血酶;
76. This protein BDA or BDB all prolonged acitivatedpartial thromboplsatin time(APTT) ,thrombin time (TT)and prothrombintime(PT),but there were some different charater between them .
在体内外凝血实验中,BDA、BDB 均能明显延长活化部分凝血活酶时间(APTT)、凝血时间(PT)及凝血酶原时间(TT),但二者的三个指标有明显差异性。
77. DYNAMIC AND LONG-LASTING EXPRESSION OF THROMBIN RECEPTOR-1 AFTER INTRACEREBRAL HEMORRHAGE IN RATS
大鼠脑出血后大脑凝血酶受体-1长时效动态表达变化
78. The changes in brain water content and the effect of thrombin on brain edema after intracerebral hemorrhage in rats
大鼠脑出血后脑含水量变化及其与凝血酶关系的研究
79. Low dose of thrombin preconditioning can attenuate the toxic effect induced by high dose of thrombin.Its acting mechanism is associated with MAPK signal transduction pathway and HSP expression, etc.
小剂量凝血酶预处理可减轻大剂量凝血酶对神经细胞的毒性作用,其作用机制与MAPK信号转导途径、HSP表达等有关。
80. Studies have confirmed that thrombin had dual effects.Low dose of thrombin has neuroprotective effect, while high dose of thrombin has cytotoxicity.
已有研究证实,凝血酶具有双向作用,小剂量可产生神经保护作用,大剂量则具有细胞毒性作用。
