uniparental

uniparental

1. K.John McLaughlin and colleagues report on their success in using uniparental embryonic stem cells to replace blood stem cells in mice.

JohnMcLaughlin博士和同事报告了利用单系胚胎干细胞替换小鼠的血液干细胞取得了成功。

2. They can, howeer, generate "uniparental" embryonic stem cell lines.Uniparental embryos with two maternal sets of chromosomes are known as parthenogenetic.

但是，他们可以产生“单系”胚胎干细胞系，带有母系的两组染色体的单系胚胎被称为单性生殖。

3. uniparental disomy

单亲二体一对染色体(均来自父或母)

4. uniparental disomy(UPD)

单亲二体型

5. uniparental homodisomy

单亲同二体

6. uniparental heterodisomy

单亲异二体

7. uniparental inhcritance

单亲性状遗传

8. uniparental homozygote

单亲纯合了

9. uniparental embryo

单亲胚

10. uniparental inheritance

单亲遗传

11. Uniparental Disomy and Genetic Diseases

单亲遗传与遗传病

12. uniparental genetics

单亲遗传学

13. Doubly uniparental inheritance

双单亲遗传

14. In their current paper, Dr.McLaughlin and colleagues tested the functionality of uniparental ES cells in adult tissues.

在他们最近的文章中，McLaughlin博士和同事测试了单系胚胎干细胞在成熟个体组织中的功能性。

15. chironomous tentans uniparental inheritance

摇蚊单体遗传

16. Since uniparental ES cells are not deried from iable embryos, their haresting and use sidesteps many of the ethical concerns that plague traditional ES cell therapies.

既然单系胚胎干细胞不是从可繁育的胚胎中获得，它们的收集和使用可以避开许多困扰着传统胚胎干细胞治疗的伦理学关注。

17. Keywords Prader-Willi Syndrome;uniparental disomy;obesity;genomic imprinting;linkage analysis;

普拉德-威利综合征;单亲二体;肥胖;基因组印记;连锁分析;

18. Maternal uniparental disomy for chromosome 7

母源第7号染色体单亲双体

19. uniparental inheritance that prevents pollen transmission of foreign DNA;

母系遗传方式可防止基因扩散；

20. Howeer, uniparental ES cell research faces the biological hurdle of genomic imprinting, in which specific gene expression patterns are dictated by the parental origin.

然而，单系胚胎干细胞研究面临着基因组印迹的生物学障碍，即特殊的基因表达模式受原始亲代的控制。

21. The researchers took a two-step approach: First they injected uniparental ES cells into wild-type blastocyts to generate chimeric animals;

研究人员采取了两步骤的方法：首先，他们将单系胚胎干细胞注入野生型的胚细胞培育嵌合体动物；

22. The scientists found that uniparental ES cells, regardless of parent-of-origin, were able to functionally reconstitute the entire hematopoietic system of adult mice.

科学家发现单系胚胎干细胞，不管其亲代来源，可以在功能上重建成年小鼠的整个造血系统。