tyrosine

tyrosine

1. Value in parenthesis means the relative percentage of tyrosine released as compared woith casein.

3括号中之数值为酪蛋白比较之相对酪胺酸释出百分比。

2. The 8 new mutations included three in genes that normally suppress the growth of tumor cells, one being the PTPRT tyrosine phosphatase gene, which is sometimes found mutated in colon cancer.

8个新的突变位点中，有3个基因通常起到抑制肿瘤细胞生长的功能，另外一个PTPRT酪氨酸磷酸酶基因在结肠癌中会发生突变。

3. FUNCTIONS: The high-tech plant extracting technology helps effectively brighten complexion, and decompounds the melanin to suppress the activation of the tyrosine enzyme and prevent melanin appearing.

<主要功能> 高新科技雪莲纯露全效美白肌肤，分解黑色素，抑制酪氨酸酶的活性，阻止黑色素形成；

4. The ABL gene encodes a tyrosine kinase whose activity is tightly regulated.

ABL基因编码一种活性受到严格调控的酪氨酸激酶。

5. The expression of tyrosine aminotransferase in SMMC-772 1cells was induced by dexamethasone in a tim e-dependent and dose- dependent manner,but the maximal induction was low.

Dex能够诱导 SMMC- 772 1细胞酪氨酸转氨酶 m RNA的表达 ,且具有剂量依赖性和时间依赖性特点 ,但诱导倍数偏低。

6. Response rates to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in cancer treatment have been surprisingly and disappointingly low.

EGFR酪氨酸激酶抑制剂在肿瘤的治疗中的反应率是出乎意料和令人失望的低。

7. FGFR3, a member of polypeptide growth factor family, is a tyrosine kinase receptor.

FGFR3是这一多肽类生长因子的家族成员之一，它是一种酪氨酸激酶受体。

8. Genistein, the tyrosine kinase inhibitors, plays the effect by an inhibiton of tyrosine phosphorlation.

Genistein是酪氨酸激酶的非特异性抑制剂，通过抑制酪氨酸的磷酸化而发挥作用。

9. MEKK2 also synergized with anti-CD3 antibody to activate JNK in T cells, and stimulation of T cells led to induction of MEKK2 tyrosine phosphorylation.

MEKK2也是JNK的强烈激活物，能激活JNK依赖的AP-1和IL-2报告基因表达。 当用抗CD28抗体刺激时MEKK2介导的JNK活性无变化，而随着抗CD3抗体刺激，MEKK2介导的JNK活性显著增加。

10. Is PDGF tyrosine kinase inhibitor effective in pancreatic cancer?

PDGF受体酪氨酸激酶抑制剂在胰腺癌中是否有作用?

11. RT-PCR discove r ed mRNA of NSE(neuron specific enolase),Nurr1,Ptx3,Lmx1b and Tyrosine hydroxy lase(TH)were positive.

RT-PCR结果显示NSE(neuron specificenolase)、Nurr1、Ptx3、Lmx1b和TH的mRNA均有表达;

12. SHP-2, a cytoplasmic SH2 domain containing protein tyrosine phosphatase is involved in the signaling pathways of a variety of growth factors and cytokines.

SHP-2，一种含有SH2区域的胞浆蛋白酪氨酸磷酸酶，参与了各种生长因子和细胞因子的信号传导过程。

13. STI571 could induce leukemia cells of ANLL into terminal differentiation by inhibiting c-kit tyrosine kinase.

STI571对急性非淋巴细胞白血病原代细胞有诱导向同系终末分化的作用,对c-kit酪氨酸激酶有明显的抑制作用,且与药物浓度相关。

14. Through b ind ing to its receptor,TPO can induce receptor d im eriza-tion and tyrosine phosphorylation,and then activate a series of signaling pathways,inc lud ing JAK /STAT,Shc /Ras/MAPK and PI3K /Akt.

TPO与其受体c-Mp l结合后,c-Mp l形成同源二聚体,激活JAK/STAT、Shc/Ras/MAPK、PI3K/Akt等信号通路,引发一系列生理效应。

15. The outcome is the absolutely deficit of insulin in the body.Some autoantigen including insulin,glutamate decarboxylase and tyrosine phosphatase maybe targeted antigen triggering t...

一些自身抗原如胰岛素、谷氨酸脱羧酶和酪氨酸磷酸酶等可能是触发该自身免疫反应的靶抗原,而细胞因子、趋化因子及炎性介质等亦参与了该免疫过程。

16. IMPLICATIONS: Sevoflurane exerts a preconditioning effect against ischemic cell death in the rat acute hippocampal slice, depending on both tyrosine kinases and duration of ischemia.

七氟烷对抗大鼠海马切片的缺血细胞死亡的预处理效果，依靠络氨酸激酶和缺血的持续时间。

17. Amino acid profiles of different sufu Products indicated that the occurrence of white particles is closely related to the amount of free tyrosine in sufu.

不同腐乳样品的游离氨基酸图谱显示了白点的出现与游离酪氨酸含量之间有密切关系。

18. Functions: Innovation and know-how come together to help effectively brighten complexion, decompounds the melanin, suppress the activation of the tyrosine enzyme, prevent melanin appearing.

主要功能：高新科技全效美白肌肤，可以分解黑色素，抑制酪氨酸酶的活性，阻止黑色素形成；

19. The advances made in the new compounds identified as Protein Tyrosine Phosphatases 1B (PTP1B) inhibitors recently and their structure-activity relationship were reviewed in this paper.

介绍了最近几年来关于酪氨酸蛋白磷酸酯酶1B作用的机制以及通过各种途径发现的结构新颖的小分子抑制剂的构效关系研究进展。

20. It is a rapid method for screening the tyrosine phenol lyase producer according to the size of the red color ring by using methyl phenol red as the indicator in the solid medium containing tyrosine.

以甲酚红作指示剂，在加有酪氨酸的固态培养基上，根据甲酚红由黄变红所形成的变色圈的大小筛选酪氨酸酚解酶高产突变株是一种平板快速筛选方法。

21. The conservation in sequence and structure of protein tyrosine phosphatases has been analyzed by aligning their sequences and superposed their three dimensional topological structures.

以蛋白质酪氨酸磷酸酶为模型，通过序列和结构的比较，对蛋白质序列、结构的保守性与其功能和进化的关系问题进行了研究。

22. The N + implantation-induced influence upon the surface charges of tyrosine and adenosine molecule crystals was studied with the method of capillary electrophoresis.

以酪氨酸（Tyr）分子晶体和腺嘌呤核苷（AR）分子晶体为对象，用毛细管电泳法研究荷能离子注入对其表面电荷的影响。

23. After treatment of MNC of CML and K562 with imatinib in vitro, the expression of DNA-PKcs protein was enhanced while tyrosine phosphorylation of bcr-abl fusion protein decreased.

伊马替尼体外作用于CML患者MNC及K562细胞后,DNA-PKcs蛋白表达量随着bcr-abl融合蛋白酪氨酸磷酸化水平的降低而升高。

24. But imatinib is known to cause heart problems in some people because it also switches off tyrosine kinases in the ABL family.

但伊马替尼是众所周知的导致心脏问题，在一些人，因为它还要开关小康酪氨酸激酶在abl的家庭。

25. Angiopoietin acts on Tie-2,which is a receptor tyrosine kinase specifically expressed on endothelial cells.

作用于内皮特异受体酪氨酸激酶酪氨酸激酶受体2。

26. One more thing that worth mentioning is that edible fungi also contains many kinds of amino acids that are needed in human body, such as leucine, isoleucine, tryptophan and tyrosine.

值得一提的是，食用菌还含有人体必需的多种氨基酸，如亮氨酸、异亮氨酸、色氨酸、酪氨酸等。

27. Tyrosine (4.6%). May slow the ageing of cells and suppresses hunger. Involved in the colouration of hair and skin, and indeed helps with sunburn protection.

减缓细胞老化,降低饥渴感,影响皮肤及头发颜色,有效防止太阳晒伤.

28. Low energy ions were produced in gas arc discharge,and the ions were accelerated into tyrosine(Tyr) aqueous solution.

分别以注入机和气体常压弧光放电产生的低能离子作用于固态和溶液中的氨基酸， 研究了样品红外光谱的变化。

29. tyrosine with one iodine atom added.

加有一个碘原子的酪氨酸。

30. tyrosine with two iodine atoms added

加有两个碘原子的酪氨酸

31. tyrosine with two iodine atoms added.

加有两个碘原子的酪氨酸。

32. SH2-eontaining tyrosine phosphatase 1 (SHP-1)

包含SH2结构域的蛋白质酪氨酸磷酸酶1（SHP-1）

33. Receptor tyrosine protein kinase is one of key kinases in cell signal transduction and plays an important role in the process of cell growth, development and functions regulated by growth factors.

受体酪氨酸蛋白激酶是细胞信号转导进行的关键信号酶,在生长因子调控细胞生长、发育与功能的过程中起着重要的生理作用。

34. Moreover, all isoflavones used in this study were found to be potent peroxynitrite scavengers, preventing the nitration of tyrosine.

另外亦发现此四种异黄酮皆可降低酪胺酸被硝化作用的程度，而表现出清除过氧化亚硝酸根能力。

35. soluble fms - like tyrosine kinase - 1 (sFlt - 1)

可溶性血管内皮生长因子受体-1（sFlt-1）

36. Gefitinib, the first EGFR tyrosine kinase inhibitor put into clinical trial, was put into market in Japan in 2002.

吉非替尼是EGFR酪氨酸激酶抑制剂中最早进入临床试验的口服药物，2002年首次于日本上市。

37. No tyrosine was found in amino acids of AFL.

在AFL的氨基酸组成中不含Tyr。

38. We detected the T790M mutation, which confers drug resistance, in circulating tumor cells collected from patients with EGFR mutations who had received tyrosine kinase inhibitors.

在从接受酪氨酸激酶抑制剂治疗患者中收集的循环肿瘤细胞中，我们检测到了引起耐药的T790M突变，

39. Tyrosine kinases are attractive as targets in the research of therapeutic agents, not only against cancer, hut also against many other diseases.

在包括癌症和其他许多疾病的治疗研究中，酪氨酸激酶都是研究的目标和对象。

40. Double fluorescence immunostain of tyrosine hydroxylase (TH) and glutamate (Glu) was used in midbrain sections of rat.

在大鼠中脑组织切片上进行酪氨酸羟化酶和谷氨酸双重免疫荧光染色。

41. Dopamine and serotonin concentrations, dopamine and 5HT uptake sites, and tyrosine and tryptophan hydroxylase activities are reduced after the administration of methamphetamine.

在服用甲基苯丙胺以后，多巴胺，复合胺含量及回收处，酪氨酸，色氨酸，羟化酶反应都有所降低。

42. In the protein of scolopendra, scorpio, pheretima,the content of Glycine, Alanine, Valine,Tyrosine,Phenylalanine and Arginie is higher,but the content of glutaminic acid is significantly lower than the daily animal and plant albumens.

在蜈蚣、全蝎、地龙三种天然动物药材中甘氨酸、丙氨酸、酪氨酸、苯丙氨酸、精氨酸含量高，谷氨酸含量则显著低于常见动植物蛋白。

43. In tyrosinase-positive oculocutaneous albinism, melanosomes contain tyrosine, a tyrosinase substrate, but a defect in the tyrosine transport system impairs melanin production.

在酪氨酸酶阳性眼皮肤白化,含有黑色素细胞酪氨酸,酪氨酸基板,但缺陷妨碍交通系统的酪氨酸黑色素生产。

44. Determination Silk Fibroin by Tyrosine Residue Oxidatiaon Reaction at Carbon Paste Eleotrode.

基于酪氨酸残基在碳糊电极上的氧化反应阳极溶出伏安法测定丝素蛋白。

45. B inhibited cells, an obvious increase inX-ray-induced mutations was observed after treatment with ELFMF incombination with X-irradiation in M054 cells with tyrosine mutant 1KB-agene other than with serine mutant 1KB-a gene or vector alone.

基因的 M054细胞X线诱导的HPRT基因突变，而对导入了丝氨酸突变体I。 B－a基因或空载体的M054细胞没有影响。

46. Roles of receptor tyrosine kinases, integrins, and Shc.

外文期刊 Mechanotransduction in response to shear stress.

47. An amino acid, C9H11NO4, formed in the liver from tyrosine and converted to dopamine in the brain.

多巴一种胺基酸，c9h11no4，由酪胺酸在肝脏中生成并在大脑中变为多巴胺

48. An amino acid,C9H11NO4,formed in the liver from tyrosine and converted to dopamine in the brain.

多巴一种胺基酸，C9H11NO4，由酪胺酸在肝脏中生成并在大脑中变为多巴胺。

49. Large protein conformational changes accompany DNA deformation, creating a bipartite catalytic site that positions the DNA backbone near a reactive tyrosine and a coordinated magnesium ion.

大型蛋白构象变化，伴随脱氧核糖核酸变形，造成偶催化站点位置脱氧核糖核酸骨干近被动酪氨酸和协调一致的镁离子。

50. It is most efficient in clearing the peptide bonds on the C-terminal side of such amino acids tyrosine.

它对裂开诸如酪氨酸这类氨基酸的羧基末端的侧肽链最为有效。

51. The adsorption of Tyrosine (Tyr) and Phenylalanine (Phe) on commercial activated carbon has been investigated for different values of PH in solution, which have been chosen to be representative of industrial operations.

实验研究了酪氨酸和苯丙氨酸在不同pH值溶液中在活性炭上的吸附平衡。

52. The results showed that CCL4and HG inhibited the GK activity,elevated Caconcen tration and decreased the level of tyrosine phosphorylation in hepatocytes.

实验结果表明,CCL4和HG均使肝细胞内葡萄糖激酶活性下降,Ca超载,并使细胞内酪氨酸磷酸化水平降低.

53. In the Piedmont cattle,the myotatin sequence contains a mis sense mutation in exon 3,resulting i n a substitution of tyrosine for an in variant cysteine in the mature region of the protein,which i s consistent with other reports previously.

对PCR扩增片段克隆、测序结果显示,2头皮埃蒙特牛均在编码序列938处发生G到A突变,使编码氨基酸由半胱氨酸变为酪氨酸,符合前人检测结果。

54. This research studied the 3，3，5，5-tetramethylbenzidine（TMB） oxidation reaction and tyrosine iodination catalyzed by thyroid peroixdase （TPO）.

对他巴唑影响甲状腺过氧化物酶（TPO）催化的四甲基联苯胺（TMB）显色反应及酪氨酸碘化反应进行了研究。

55. As for the total scores of tobacco, arginine, phenylalanine, serine, total free amnio acids and tyrosine have big contribution.

对评吸总分贡献较大的有精氨酸、丙氨酸、氨酸、游离氨基酸和酪氨酸。

56. The tyrosine phosphorylation of leptin receptor was revealed by immuno precipitation.

应用免疫沉淀法检测瘦素受体的酪氨酸磷酸化程度。

57. Isoflavone. Inhibitor of EGFR tyrosine kinase, blocking phosphatidylinositol turnover.

异黄酮类。抑制EGFR酪氨酸激酶。阻断磷脂酰肌糖的翻转。

58. We are interested in the identification of novel components in Drosophila EGF receptor tyrosine kinase (RTK) signal transduction pathway.

我们主要的兴趣在于用遗传学及分子生物学的方法来研究果蝇的胚胎发育过程。

59. All MAPKs contain a threonine -X-tyrosine motif and require phosphorylation of both threonine and tyrosine for activation.

所有的MAPK都含有一个苏氨酸-X-酪氨酸基序,并需要在苏氨酸及酪氨酸两者都被磷酸化之后才能激活。

60. All these actions of VEGF are mediated by receptor tyrosine kinase, vascular endothelial growth factor receptor (VEGFR).

所有这些作用都是通过血管内皮生长因子受体信号转导通路实现的。

61. The cancer cells don t destroy the conjugated double bond structure of the aromatic amino acids in protein,but consume unequally the quantity of tyrosine and tryptophane.

把吸收光谱与荧光光谱结合起来,对癌症的早期诊断也有一定的参考价值。

62. In the paper, the strains producing high-yield tyrosinase were selected by using the plate and culture fluid contained Tyrosine.

报道了用含酪氨基酸的平板和培养液筛选高产酪氨酸酶菌株的方法。

63. The abnormal activity of tyrosine protein kinase was the cause with endometrium abnormal growth.

提示rrPK活性异常是引起子宫内膜异常增生的原因。

64. This indicates that tyrosine possesses organ specificity to nucleic acid metabolism.

提示酪氨酸对核酸代谢的影响有器官特异性。

65. EGFR tyrosine kinase inhibitor is an investigative hot spot in targeted therapy of non-small cell lung cancer (NSCLC).

摘要EGFR靶向抑制剂，是目前NSCLC靶向治疗的研究热点之一。

66. Receptor tyrosine kinase (RTK), a membrane receptor superfamily with intrinsic protein tyrosine kinase activity, has many members and complicated signal transduction pathways.

摘要受体酪氨酸激酶是一个具有内在酪氨酸蛋白激酶活性的膜受体超家族，成员众多，信号转导通路复杂多样。

67. Gefitinib (Iressa, ZD1839), a specific tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR), is a novel molecular-targeting antineoplastic agent.

摘要吉非替尼是一种新型的分子靶向抗癌药物，它选择性抑制表皮生长因子受体酪氨酸激酶而发挥作用。

68. The partial least square (PLS) method for spectrophotometric simultaneous determination of phenylalanine, tryptophan and tyrosine in the mixed amino acids was studied.

摘要本文将偏最小二乘法(PLS)用于分光光度法同时测定混合氨基酸体系中的苯丙氨酸、色氨酸和酪氨酸。

69. A 3D database searching was conducted with 3DFS in 3D database using the pharmacophore of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors.

摘要用表皮生长因子受体酪氨酸激酶抑制剂的药效团作为提问结构在三维数据库中进行了搜索。

70. Objective To approach the mechanism of action of anticancer and the investigation progress of protein tyrosine kinase (PTK).

摘要目的探讨蛋白酪氨酸激酶抑制剂抗肿瘤作用机理及其研究进展。

71. Sorafenib, a novel, oral multi-kinase inhibitor, targets on serine/threonine and receptor tyrosine kinases of the tumor cells and vasculature; blocks the signal transconduction and inhibits tumor growth.

摘要索拉非尼是首个口服多激酶抑制药，靶向作用于肿瘤细胞和肿瘤血管上的丝氨酸和（或）苏氨酸及受体酪氨酸激酶，阻断信号传导，抑制肿瘤生长。

72. Protein tyrosine nitration is a biomarker of NO-dependent oxidative stress.

摘要蛋白质酪氨酸硝化是一氧化氮依赖的氧化应激的生物标志。

73. Protein tyrosine nitration is an important selective post-translational modification, and the product, 3-nitrotyrosine, has been utilized as a biomarker of tissue and cell injury.

摘要蛋白质酪氨酸硝化是一种重要的蛋白质翻译后的选择性修饰，其产物3-硝基酪氨酸可以作为检测细胞和组织损伤的一个生物标志。

74. Abstract： Brain-derived neurotrophic factor （BDNF） can increase the excitability of hippocampus by activating its receptor tyrosine kinase B and then result in temporal epilepsy.

摘要： 脑源性神经营养因子（BDNF）激活其受体酪氨酸受体激酶B，使海马兴奋性增高，从而促使颞叶癫痫产生。

75. Abstract: Protein tyrosine nitration is an important posttranslational modification involving a variety of diseases.

文章摘要: 蛋白质酪氨酸硝基化是一种重要的蛋白质翻译后修饰，与多种病症相关。

76. Methods:Messenger RNA of tyrosine aminotransferase were determined by quantitative RT- PCR.

方法 :采用定量逆转录 -多聚酶链反应 (RT- PCR)检测酪氨酸转氨酶 m RNA。

77. Methods:after musculal injection of progesterone at high and low dosage for one month in female mice,tyrosine and MDA in skin and liver were measured,and skin melanocyte was observed.

方法:用黄体酮注射液(高、低两个剂量组)攻击雌性小鼠1个月,以皮肤、肝脏组织酪氨酸、MDA含量变化及皮肤黑色素细胞病理形态学指标作为考察模型是否成功的依据。

78. Methods: Immunohistochemistry technology and high-pressure liquid chromatography with electrochemical detector (HPLC-EC) were used to evaluated tyrosine hydroxylase (TH) and DA .

方法:采用免疫组化技术和高效液相-电化学法(HPLC-EC)分别对酪氨酸羟化酶(TH)、DA进行了含量测定。

79. METHODS The tyrptophane and tyrosine contents were determined with three -wavelength spectrophotometry.

方法：运用三波长分光光度法测定色氨酸和酪氨酸的含量。

80. Trastuzumab is a monoclonal antibody that directly targets part of the HER2 tyrosine kinase receptor.

曲妥单抗是一种直接针对HER2酪氨酸激酶受体的单抗。